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Protein

Putative cytochrome P450 CYP13A4

Gene

cyp-13A4

Organism
Caenorhabditis elegans
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Cytochromes P450 are a group of heme-thiolate monooxygenases. They oxidize a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.

Cofactori

hemeBy similarity

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi464Iron (heme axial ligand)By similarity1

GO - Molecular functioni

Keywordsi

Molecular functionMonooxygenase, Oxidoreductase
LigandHeme, Iron, Metal-binding

Enzyme and pathway databases

ReactomeiR-CEL-211958 Miscellaneous substrates
R-CEL-211979 Eicosanoids
R-CEL-211981 Xenobiotics
R-CEL-2162123 Synthesis of Prostaglandins (PG) and Thromboxanes (TX)
R-CEL-5423646 Aflatoxin activation and detoxification
R-CEL-9027307 Biosynthesis of maresin-like SPMs

Names & Taxonomyi

Protein namesi
Recommended name:
Putative cytochrome P450 CYP13A4 (EC:1.14.-.-)
Gene namesi
Name:cyp-13A4
Synonyms:cyp13a4
ORF Names:T10B9.1
OrganismiCaenorhabditis elegans
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
Proteomesi
  • UP000001940 Componenti: Chromosome II

Organism-specific databases

WormBaseiT10B9.1 ; CE01654 ; WBGene00011671 ; cyp-13A4

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000522641 – 520Putative cytochrome P450 CYP13A4Add BLAST520

Proteomic databases

PaxDbiQ27513
PeptideAtlasiQ27513

Expressioni

Gene expression databases

BgeeiWBGene00011671

Interactioni

Protein-protein interaction databases

STRINGi6239.T10B9.1

Structurei

3D structure databases

ProteinModelPortaliQ27513
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the cytochrome P450 family.Curated

Phylogenomic databases

eggNOGiKOG0158 Eukaryota
COG2124 LUCA
GeneTreeiENSGT00900000140779
HOGENOMiHOG000016177
InParanoidiQ27513
KOiK17861
OMAiVERRVEW
OrthoDBiEOG091G0JNC
PhylomeDBiQ27513

Family and domain databases

Gene3Di1.10.630.10, 1 hit
InterProiView protein in InterPro
IPR001128 Cyt_P450
IPR017972 Cyt_P450_CS
IPR002401 Cyt_P450_E_grp-I
IPR036396 Cyt_P450_sf
PfamiView protein in Pfam
PF00067 p450, 1 hit
PRINTSiPR00463 EP450I
PR00385 P450
SUPFAMiSSF48264 SSF48264, 1 hit
PROSITEiView protein in PROSITE
PS00086 CYTOCHROME_P450, 1 hit

Sequencei

Sequence statusi: Complete.

Q27513-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSLSLLIAGA LFIGFLTYYI WIWSFWIRKG VKGPRGFPFF GVILKFHDYE
60 70 80 90 100
NPGLLKLGEW TKKYGSIYGI TEGVEKTLVV SNPEFVHEVF VKQFDNFYGR
110 120 130 140 150
KTNPIQGDPN KNKRAHLVLA QGHRWKRLRT LASPTFSNKS LRKIMSTVEE
160 170 180 190 200
TVVELMRHLD EASAKGKAVD LLDYYQEFTL DIIGRIAMGQ TESLMFRNPM
210 220 230 240 250
LPKVKEIFKK GGKMPFLIAG VFPIAGTLMR QLFMKFPKFS PAFGIMNTME
260 270 280 290 300
KALNKRLEQR AADKKAGIEP SGEPQDFIDL FLDARANVDF IEEESTLGFA
310 320 330 340 350
KSEVLKVDKH LTFDEIIGQL FVFLLAGYDT TALSLSYSSY LLATHPEIQK
360 370 380 390 400
KLQEEVDREC PDPEVTFDQI SKLKYMECVV KEALRMYPLA SLVHNRKCMK
410 420 430 440 450
KTNVLGVEID EGTNVQVDTW TLHYDPKVWG DDASEFKPER WETGDELFYA
460 470 480 490 500
KGGYLPFGMG PRICIGMRLA MMEEKLLLTH ILKKYTFDTS TETEIPLKLV
510 520
GSATIAPRNV MLKLTPRHSN
Length:520
Mass (Da):59,371
Last modified:November 1, 1997 - v1
Checksum:i996C1172B8D64E93
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z48717 Genomic DNA Translation: CAA88603.1
PIRiT24777
RefSeqiNP_496111.1, NM_063710.1
UniGeneiCel.14407

Genome annotation databases

EnsemblMetazoaiT10B9.1; T10B9.1; WBGene00011671
GeneIDi188355
KEGGicel:CELE_T10B9.1
UCSCiT10B9.1 c. elegans

Similar proteinsi

Entry informationi

Entry nameiC13A4_CAEEL
AccessioniPrimary (citable) accession number: Q27513
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: November 1, 1997
Last modified: May 23, 2018
This is version 121 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programCaenorhabditis annotation project

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Caenorhabditis elegans
    Caenorhabditis elegans: entries, gene names and cross-references to WormBase
  2. SIMILARITY comments
    Index of protein domains and families

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