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Protein

Serine/threonine-protein phosphatase

Gene

CELE_F49E11.7

Organism
Caenorhabditis elegans
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

[a protein]-serine/threonine phosphate + H2O = [a protein]-serine/threonine + phosphate.UniRule annotation

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

HydrolaseUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Serine/threonine-protein phosphataseUniRule annotation (EC:3.1.3.16UniRule annotation)
Gene namesi
ORF Names:CELE_F49E11.7Imported, F49E11.7Imported
OrganismiCaenorhabditis elegansImported
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
Proteomesi
  • UP000001940 Componenti: Chromosome IV

Organism-specific databases

WormBaseiF49E11.7; CE05903; WBGene00009893.

PTM / Processingi

Proteomic databases

PaxDbiQ27500.

Interactioni

Protein-protein interaction databases

STRINGi6239.F49E11.7.

Structurei

3D structure databases

ProteinModelPortaliQ27500.
SMRiQ27500. Positions 8-312.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini133 – 1386SER_THR_PHOSPHATASEInterPro annotation

Sequence similaritiesi

Belongs to the PPP phosphatase family.UniRule annotation

Phylogenomic databases

eggNOGiKOG0374. Eukaryota.
COG0639. LUCA.
GeneTreeiENSGT00530000062911.
HOGENOMiHOG000172697.
InParanoidiQ27500.
KOiK01090.
OMAiDETTHIE.
OrthoDBiEOG7V76BC.

Family and domain databases

Gene3Di3.60.21.10. 1 hit.
InterProiIPR004843. Calcineurin-like_PHP_apaH.
IPR029052. Metallo-depent_PP-like.
IPR006186. Ser/Thr-sp_prot-phosphatase.
[Graphical view]
PfamiPF00149. Metallophos. 1 hit.
[Graphical view]
PRINTSiPR00114. STPHPHTASE.
SMARTiSM00156. PP2Ac. 1 hit.
[Graphical view]
SUPFAMiSSF56300. SSF56300. 1 hit.
PROSITEiPS00125. SER_THR_PHOSPHATASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q27500-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTDDKKMFDI NEFLKRHLFV KNWVNYRQQS YTKYELMQLI ESVEAALSVD
60 70 80 90 100
DTLAKISPPV TIVGDIHGQY PDLVRVLCNQ NSKEDAKKKA AYGFCNSRFV
110 120 130 140 150
FLGDYVDRGH HSIECISLVF ALKVVYPTNY ILLRGNHETK SINYTYGFRE
160 170 180 190 200
ELVNRLGPID GFEIWERFNV AFSWMPLACL VGHKILCMHG GISPKLHSLK
210 220 230 240 250
EINEIDRPVA EILPDSLAQD LLWADPADGQ GAMTVRSTPE YVPNGVRGLS
260 270 280 290 300
FIFNEAAVRD TCKRLNINLI VRAHQMIPEG FKFFADQKLL TIFSAPRYMN
310 320 330 340 350
ETDNHGATLR VETDGKLNIG RFRHKKLLHA NSADEITRGD DIPNLERKKS
360 370 380
GSMPVKHLKT SSSSSPSHSN GKSKGGEGLS LGKI
Length:384
Mass (Da):43,316
Last modified:October 31, 2012 - v3
Checksum:iED306C2AB7C5AA53
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284604 Genomic DNA. Translation: CAA94346.3.
PIRiT22434.
RefSeqiNP_502500.3. NM_070099.3.

Genome annotation databases

EnsemblMetazoaiF49E11.7; F49E11.7; WBGene00009893.
GeneIDi186051.
KEGGicel:CELE_F49E11.7.
UCSCiF49E11.7. c. elegans.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284604 Genomic DNA. Translation: CAA94346.3.
PIRiT22434.
RefSeqiNP_502500.3. NM_070099.3.

3D structure databases

ProteinModelPortaliQ27500.
SMRiQ27500. Positions 8-312.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi6239.F49E11.7.

Proteomic databases

PaxDbiQ27500.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiF49E11.7; F49E11.7; WBGene00009893.
GeneIDi186051.
KEGGicel:CELE_F49E11.7.
UCSCiF49E11.7. c. elegans.

Organism-specific databases

CTDi186051.
WormBaseiF49E11.7; CE05903; WBGene00009893.

Phylogenomic databases

eggNOGiKOG0374. Eukaryota.
COG0639. LUCA.
GeneTreeiENSGT00530000062911.
HOGENOMiHOG000172697.
InParanoidiQ27500.
KOiK01090.
OMAiDETTHIE.
OrthoDBiEOG7V76BC.

Family and domain databases

Gene3Di3.60.21.10. 1 hit.
InterProiIPR004843. Calcineurin-like_PHP_apaH.
IPR029052. Metallo-depent_PP-like.
IPR006186. Ser/Thr-sp_prot-phosphatase.
[Graphical view]
PfamiPF00149. Metallophos. 1 hit.
[Graphical view]
PRINTSiPR00114. STPHPHTASE.
SMARTiSM00156. PP2Ac. 1 hit.
[Graphical view]
SUPFAMiSSF56300. SSF56300. 1 hit.
PROSITEiPS00125. SER_THR_PHOSPHATASE. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Genome sequence of the nematode C. elegans: a platform for investigating biology."
    Caenorhabditis elegans Sequencing Consortium
    Sulson J.E., Waterston R.
    Science 282:2012-2018(1998) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Bristol N2Imported.

Entry informationi

Entry nameiQ27500_CAEEL
AccessioniPrimary (citable) accession number: Q27500
Entry historyi
Integrated into UniProtKB/TrEMBL: November 1, 1996
Last sequence update: October 31, 2012
Last modified: June 8, 2016
This is version 126 of the entry and version 3 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.