Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

CYtochrome P450 family

Gene

cyp-33e1

Organism
Caenorhabditis elegans
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

MonooxygenaseUniRule annotation, Oxidoreductase

Keywords - Ligandi

HemeUniRule annotation, Iron, Metal-binding

Enzyme and pathway databases

ReactomeiR-CEL-156581. Methylation.
R-CEL-193048. Androgen biosynthesis.
R-CEL-193993. Mineralocorticoid biosynthesis.
R-CEL-194002. Glucocorticoid biosynthesis.
R-CEL-211957. Aromatic amines can be N-hydroxylated or N-dealkylated by CYP1A2.
R-CEL-211976. Endogenous sterols.
R-CEL-211981. Xenobiotics.
R-CEL-2142670. Synthesis of epoxy (EET) and dihydroxyeicosatrienoic acids (DHET).
R-CEL-2142816. Synthesis of (16-20)-hydroxyeicosatetraenoic acids (HETE).
R-CEL-5423646. Aflatoxin activation and detoxification.

Names & Taxonomyi

Protein namesi
Submitted name:
CYtochrome P450 familyImported
Gene namesi
Name:cyp-33e1Imported
Synonyms:cyp-33E1Imported
ORF Names:C49C8.4Imported, CELE_C49C8.4Imported
OrganismiCaenorhabditis elegansImported
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
Proteomesi
  • UP000001940 Componenti: Chromosome IV

Organism-specific databases

WormBaseiC49C8.4; CE31452; WBGene00016768; cyp-33E1.

PTM / Processingi

Proteomic databases

EPDiQ27482.
PaxDbiQ27482.
PRIDEiQ27482.

Interactioni

Protein-protein interaction databases

DIPiDIP-27047N.
MINTiMINT-1104610.
STRINGi6239.C49C8.4.

Structurei

3D structure databases

ProteinModelPortaliQ27482.
SMRiQ27482. Positions 24-493.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the cytochrome P450 family.UniRule annotation

Phylogenomic databases

eggNOGiKOG0156. Eukaryota.
COG2124. LUCA.
GeneTreeiENSGT00760000118992.
HOGENOMiHOG000036993.
InParanoidiQ27482.
KOiK17955.
OrthoDBiEOG7RBZ85.
PhylomeDBiQ27482.

Family and domain databases

Gene3Di1.10.630.10. 1 hit.
InterProiIPR001128. Cyt_P450.
IPR017972. Cyt_P450_CS.
IPR002401. Cyt_P450_E_grp-I.
[Graphical view]
PfamiPF00067. p450. 1 hit.
[Graphical view]
PRINTSiPR00463. EP450I.
PR00385. P450.
SUPFAMiSSF48264. SSF48264. 1 hit.
PROSITEiPS00086. CYTOCHROME_P450. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q27482-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MILLILTSIL IIYLFNHFYW KRRKLPPGPI PLPIIGNLYL MTEDVKPGYK
60 70 80 90 100
MYEKLKDKYG PVFTFWLANL PMVTVTDWKL IKQHFIKDGA NFVGRPEFPI
110 120 130 140 150
SMEMRQGPYG IIESHGDRWI QQRRFALHIL RDFGLGKNLM EEKVLGEVTA
160 170 180 190 200
MIDSIRKSME DVDMQNIFDA SVGSVINNML FGYRYDETNI EEFLELKNRM
210 220 230 240 250
NKHFKLAAEP MGGLIGMNPW LGHLPFFKGY KNVIMHNWMG LMEMFRKQAT
260 270 280 290 300
DRLASIDYDS DEYSDYVEAF LKERKKHENE QDFGGFEMEQ LDSVCFDLWV
310 320 330 340 350
AGMETTSNTL NWALLYVLLN PEVRQKVYEE LEREIGSDRI ITTTDRPKLN
360 370 380 390 400
YINATVNESQ RLANLLPMNL SRSTNADVEI AGYRIPKDTV ITPQISSVMY
410 420 430 440 450
DPEIFPEPYE FKPERFLESD GSLKKVEELV PFSIGKRQCL GEGLAKMELF
460 470 480 490
LYFANLFNKF DIKFHESNPN PSIKKEVGVT MKAKNYRVSM KERY
Length:494
Mass (Da):57,676
Last modified:October 1, 2002 - v2
Checksum:iA4498ABF20BD1E66
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284604 Genomic DNA. Translation: CCD67644.1.
PIRiT29849.
RefSeqiNP_501480.2. NM_069079.5.
UniGeneiCel.7958.

Genome annotation databases

EnsemblMetazoaiC49C8.4; C49C8.4; WBGene00016768.
GeneIDi183602.
KEGGicel:CELE_C49C8.4.
UCSCiC49C8.4. c. elegans.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284604 Genomic DNA. Translation: CCD67644.1.
PIRiT29849.
RefSeqiNP_501480.2. NM_069079.5.
UniGeneiCel.7958.

3D structure databases

ProteinModelPortaliQ27482.
SMRiQ27482. Positions 24-493.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

DIPiDIP-27047N.
MINTiMINT-1104610.
STRINGi6239.C49C8.4.

Proteomic databases

EPDiQ27482.
PaxDbiQ27482.
PRIDEiQ27482.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiC49C8.4; C49C8.4; WBGene00016768.
GeneIDi183602.
KEGGicel:CELE_C49C8.4.
UCSCiC49C8.4. c. elegans.

Organism-specific databases

CTDi183602.
WormBaseiC49C8.4; CE31452; WBGene00016768; cyp-33E1.

Phylogenomic databases

eggNOGiKOG0156. Eukaryota.
COG2124. LUCA.
GeneTreeiENSGT00760000118992.
HOGENOMiHOG000036993.
InParanoidiQ27482.
KOiK17955.
OrthoDBiEOG7RBZ85.
PhylomeDBiQ27482.

Enzyme and pathway databases

ReactomeiR-CEL-156581. Methylation.
R-CEL-193048. Androgen biosynthesis.
R-CEL-193993. Mineralocorticoid biosynthesis.
R-CEL-194002. Glucocorticoid biosynthesis.
R-CEL-211957. Aromatic amines can be N-hydroxylated or N-dealkylated by CYP1A2.
R-CEL-211976. Endogenous sterols.
R-CEL-211981. Xenobiotics.
R-CEL-2142670. Synthesis of epoxy (EET) and dihydroxyeicosatrienoic acids (DHET).
R-CEL-2142816. Synthesis of (16-20)-hydroxyeicosatetraenoic acids (HETE).
R-CEL-5423646. Aflatoxin activation and detoxification.

Family and domain databases

Gene3Di1.10.630.10. 1 hit.
InterProiIPR001128. Cyt_P450.
IPR017972. Cyt_P450_CS.
IPR002401. Cyt_P450_E_grp-I.
[Graphical view]
PfamiPF00067. p450. 1 hit.
[Graphical view]
PRINTSiPR00463. EP450I.
PR00385. P450.
SUPFAMiSSF48264. SSF48264. 1 hit.
PROSITEiPS00086. CYTOCHROME_P450. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Genome sequence of the nematode C. elegans: a platform for investigating biology."
    Caenorhabditis elegans Sequencing Consortium
    Sulson J.E., Waterston R.
    Science 282:2012-2018(1998) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Bristol N2Imported.

Entry informationi

Entry nameiQ27482_CAEEL
AccessioniPrimary (citable) accession number: Q27482
Entry historyi
Integrated into UniProtKB/TrEMBL: November 1, 1996
Last sequence update: October 1, 2002
Last modified: July 6, 2016
This is version 131 of the entry and version 2 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.