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Protein
Submitted name:

CYtochrome P450 family

Gene

cyp-25a4

Organism
Caenorhabditis elegans
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

GO - Molecular functioni

Keywordsi

Molecular functionMonooxygenaseUniRule annotation, Oxidoreductase
LigandHemeUniRule annotation, Iron, Metal-binding

Enzyme and pathway databases

ReactomeiR-CEL-211958. Miscellaneous substrates.
R-CEL-211979. Eicosanoids.
R-CEL-211981. Xenobiotics.
R-CEL-2162123. Synthesis of Prostaglandins (PG) and Thromboxanes (TX).
R-CEL-5423646. Aflatoxin activation and detoxification.

Names & Taxonomyi

Protein namesi
Submitted name:
CYtochrome P450 familyImported
Gene namesi
Name:cyp-25a4Imported
Synonyms:cyp-25A4Imported
ORF Names:C36A4.6Imported, CELE_C36A4.6Imported
OrganismiCaenorhabditis elegansImported
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
Proteomesi
  • UP000001940 Componenti: Chromosome III

Organism-specific databases

WormBaseiC36A4.6; CE03074; WBGene00007967; cyp-25A4.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei6 – 22HelicalSequence analysisAdd BLAST17

GO - Cellular componenti

Keywords - Cellular componenti

Membrane

PTM / Processingi

Proteomic databases

PaxDbiQ27479.
PeptideAtlasiQ27479.

Expressioni

Gene expression databases

BgeeiWBGene00007967.

Interactioni

Protein-protein interaction databases

STRINGi6239.C36A4.6.

Structurei

3D structure databases

ProteinModelPortaliQ27479.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the cytochrome P450 family.UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiKOG0158. Eukaryota.
COG2124. LUCA.
GeneTreeiENSGT00760000118816.
HOGENOMiHOG000021810.
InParanoidiQ27479.
OMAiNCFAFLI.
OrthoDBiEOG091G0JNC.
PhylomeDBiQ27479.

Family and domain databases

InterProiView protein in InterPro
IPR001128. Cyt_P450.
IPR017972. Cyt_P450_CS.
IPR002401. Cyt_P450_E_grp-I.
PfamiView protein in Pfam
PF00067. p450. 1 hit.
PRINTSiPR00463. EP450I.
PR00385. P450.
SUPFAMiSSF48264. SSF48264. 1 hit.
PROSITEiView protein in PROSITE
PS00086. CYTOCHROME_P450. 1 hit.

Sequencei

Sequence statusi: Complete.

Q27479-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAILIISTIF FTIITFISYS IWRRHAIFKL RSSIGIPGPP VHWLWGNLNI
60 70 80 90 100
IKDRVSRLGY NDTTQWHPTL HTKYGPIFGL YCGTQLHITV SEEEDIKEIF
110 120 130 140 150
IQNFSNFSDR MTPDIFGMNQ LNQSLLQNTY ATGWKHTRSA IAPIFSTGKM
160 170 180 190 200
KAMHETLVSK IDIFLEVLKE KSSSGQKWDI FENFQSLSLD IIGKCAFAID
210 220 230 240 250
SNCQRDRTDL FYVQARKFVG AVDLKKSWIL PVSLILPELS WLWRFLYKFS
260 270 280 290 300
DLSAAELPLV KGLVDLYDRR RAGEGGNDST DLLNLLIRRE TIGKMTQREV
310 320 330 340 350
IENCFAFLIA GYETTSTAMM FSAYLLAEYP IVQQKLYEEI KKTKENAGLN
360 370 380 390 400
YDSIHNMKYL DCVYKESLRF YPPTTHFTNR VCLNDMTIRG QIYPEDSTLK
410 420 430 440 450
VQPYTIHRNP ANWESPDEFQ PERFENWEEK SSSLKWIPFG VGPRYCVGMR
460 470 480 490 500
FAEMEFKTTI AKLLDTFELS LVPGDPPMIP ETNGVIFRPR SPVRLNLKLR

I
Length:501
Mass (Da):57,987
Last modified:November 1, 1996 - v1
Checksum:i3454A6051687EFEE
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284603 Genomic DNA. Translation: CAA91272.1.
PIRiT19766.
RefSeqiNP_497779.1. NM_065378.1.
UniGeneiCel.10739.

Genome annotation databases

EnsemblMetazoaiC36A4.6; C36A4.6; WBGene00007967.
GeneIDi183248.
KEGGicel:CELE_C36A4.6.
UCSCiC36A4.6. c. elegans.

Similar proteinsi

Entry informationi

Entry nameiQ27479_CAEEL
AccessioniPrimary (citable) accession number: Q27479
Entry historyiIntegrated into UniProtKB/TrEMBL: November 1, 1996
Last sequence update: November 1, 1996
Last modified: August 30, 2017
This is version 131 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported