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Protein

Serine/threonine-protein phosphatase

Gene

C34D4.2

Organism
Caenorhabditis elegans
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

Catalytic activityi

[a protein]-serine/threonine phosphate + H2O = [a protein]-serine/threonine + phosphate.UniRule annotation

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

HydrolaseUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Serine/threonine-protein phosphataseUniRule annotation (EC:3.1.3.16UniRule annotation)
Gene namesi
ORF Names:C34D4.2Imported, CELE_C34D4.2Imported
OrganismiCaenorhabditis elegansImported
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
Proteomesi
  • UP000001940 Componenti: Chromosome IV

Organism-specific databases

WormBaseiC34D4.2; CE29211; WBGene00016398.

PTM / Processingi

Proteomic databases

PaxDbiQ27475.
PRIDEiQ27475.

Expressioni

Gene expression databases

ExpressionAtlasiQ27475. baseline and differential.

Interactioni

Protein-protein interaction databases

DIPiDIP-26580N.
MINTiMINT-1080543.
STRINGi6239.C34D4.2.

Structurei

3D structure databases

ProteinModelPortaliQ27475.
SMRiQ27475. Positions 46-312.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini135 – 1406SER_THR_PHOSPHATASEInterPro annotation

Sequence similaritiesi

Belongs to the PPP phosphatase family.UniRule annotation

Phylogenomic databases

eggNOGiKOG0374. Eukaryota.
COG0639. LUCA.
GeneTreeiENSGT00530000062911.
HOGENOMiHOG000172697.
InParanoidiQ27475.
KOiK01090.
OMAiSNALYDA.
OrthoDBiEOG7KM5XN.
PhylomeDBiQ27475.

Family and domain databases

Gene3Di3.60.21.10. 1 hit.
InterProiIPR004843. Calcineurin-like_PHP_apaH.
IPR029052. Metallo-depent_PP-like.
IPR006186. Ser/Thr-sp_prot-phosphatase.
[Graphical view]
PfamiPF00149. Metallophos. 1 hit.
[Graphical view]
PRINTSiPR00114. STPHPHTASE.
SMARTiSM00156. PP2Ac. 1 hit.
[Graphical view]
SUPFAMiSSF56300. SSF56300. 1 hit.
PROSITEiPS00125. SER_THR_PHOSPHATASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q27475-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MATPDTSAAK MAGQDRQKLK VVAWLQNLVE RLKGWTPGHC QKLFDEKELI
60 70 80 90 100
QLCYRAREVF WKNNVKLELK APVKICGDLH GQYEDLLALL ELNGWPPETK
110 120 130 140 150
YLFLGDYVDR GPFSIEVISL LFAYQVLHPD KVFLLRGNHE SRPVNMQYGF
160 170 180 190 200
FMECRKRFSN ALYDAFQLAF YCMPLCAVVS DKIICMHGGI SEDLVDLRQL
210 220 230 240 250
DKVERPCDVP DIGVIADLTW ADPDATIQMY AESQRGAGRV FGAEAVKKFL
260 270 280 290 300
NTHHLELVVR AHQVVMDGYE FFADRQLVTI FSAPSYCGQM DNAAAVMTVD
310 320
EELVCSFTVM RPDLKKDKEK KAAVGIVPN
Length:329
Mass (Da):37,336
Last modified:December 1, 2001 - v2
Checksum:iCF993072A961599C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284604 Genomic DNA. Translation: CCD66598.1.
PIRiT29290.
RefSeqiNP_501125.1. NM_068724.3.
UniGeneiCel.13387.

Genome annotation databases

EnsemblMetazoaiC34D4.2; C34D4.2; WBGene00016398.
GeneIDi177489.
KEGGicel:CELE_C34D4.2.
UCSCiC34D4.2. c. elegans.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284604 Genomic DNA. Translation: CCD66598.1.
PIRiT29290.
RefSeqiNP_501125.1. NM_068724.3.
UniGeneiCel.13387.

3D structure databases

ProteinModelPortaliQ27475.
SMRiQ27475. Positions 46-312.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

DIPiDIP-26580N.
MINTiMINT-1080543.
STRINGi6239.C34D4.2.

Proteomic databases

PaxDbiQ27475.
PRIDEiQ27475.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiC34D4.2; C34D4.2; WBGene00016398.
GeneIDi177489.
KEGGicel:CELE_C34D4.2.
UCSCiC34D4.2. c. elegans.

Organism-specific databases

CTDi177489.
WormBaseiC34D4.2; CE29211; WBGene00016398.

Phylogenomic databases

eggNOGiKOG0374. Eukaryota.
COG0639. LUCA.
GeneTreeiENSGT00530000062911.
HOGENOMiHOG000172697.
InParanoidiQ27475.
KOiK01090.
OMAiSNALYDA.
OrthoDBiEOG7KM5XN.
PhylomeDBiQ27475.

Miscellaneous databases

NextBioi897054.

Gene expression databases

ExpressionAtlasiQ27475. baseline and differential.

Family and domain databases

Gene3Di3.60.21.10. 1 hit.
InterProiIPR004843. Calcineurin-like_PHP_apaH.
IPR029052. Metallo-depent_PP-like.
IPR006186. Ser/Thr-sp_prot-phosphatase.
[Graphical view]
PfamiPF00149. Metallophos. 1 hit.
[Graphical view]
PRINTSiPR00114. STPHPHTASE.
SMARTiSM00156. PP2Ac. 1 hit.
[Graphical view]
SUPFAMiSSF56300. SSF56300. 1 hit.
PROSITEiPS00125. SER_THR_PHOSPHATASE. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Genome sequence of the nematode C. elegans: a platform for investigating biology."
    Caenorhabditis elegans Sequencing Consortium
    Sulson J.E., Waterston R.
    Science 282:2012-2018(1998) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Bristol N2Imported.

Entry informationi

Entry nameiQ27475_CAEEL
AccessioniPrimary (citable) accession number: Q27475
Entry historyi
Integrated into UniProtKB/TrEMBL: November 1, 1996
Last sequence update: December 1, 2001
Last modified: May 11, 2016
This is version 116 of the entry and version 2 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.