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Protein
Submitted name:

CYtochrome P450 family

Gene

cyp-23a1

Organism
Caenorhabditis elegans
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

GO - Molecular functioni

Keywordsi

Molecular functionMonooxygenaseUniRule annotation, Oxidoreductase
LigandHemeUniRule annotation, Iron, Metal-binding

Enzyme and pathway databases

ReactomeiR-CEL-196791. Vitamin D (calciferol) metabolism.
R-CEL-211916. Vitamins.
R-CEL-211935. Fatty acids.
R-CEL-211958. Miscellaneous substrates.
R-CEL-211981. Xenobiotics.
R-CEL-2142670. Synthesis of epoxy (EET) and dihydroxyeicosatrienoic acids (DHET).
R-CEL-2142816. Synthesis of (16-20)-hydroxyeicosatetraenoic acids (HETE).

Names & Taxonomyi

Protein namesi
Submitted name:
CYtochrome P450 familyImported
Gene namesi
Name:cyp-23a1Imported
Synonyms:cyp-23A1Imported
ORF Names:B0304.3Imported, CELE_B0304.3Imported
OrganismiCaenorhabditis elegansImported
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
Proteomesi
  • UP000001940 Componenti: Chromosome II

Organism-specific databases

WormBaseiB0304.3; CE27050; WBGene00015135; cyp-23A1.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei7 – 25HelicalSequence analysisAdd BLAST19
Transmembranei31 – 47HelicalSequence analysisAdd BLAST17

Keywords - Cellular componenti

Membrane

PTM / Processingi

Proteomic databases

EPDiQ27465.
PaxDbiQ27465.

Expressioni

Gene expression databases

BgeeiWBGene00015135.

Interactioni

Protein-protein interaction databases

STRINGi6239.B0304.3.

Structurei

3D structure databases

ProteinModelPortaliQ27465.
SMRiQ27465.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the cytochrome P450 family.UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiKOG0156. Eukaryota.
COG2124. LUCA.
GeneTreeiENSGT00900000140831.
HOGENOMiHOG000036993.
InParanoidiQ27465.
KOiK17946.
OMAiAVCVGNI.
OrthoDBiEOG091G0BT8.
PhylomeDBiQ27465.

Family and domain databases

Gene3Di1.10.630.10. 1 hit.
InterProiView protein in InterPro
IPR001128. Cyt_P450.
IPR017972. Cyt_P450_CS.
IPR002401. Cyt_P450_E_grp-I.
IPR036396. Cyt_P450_sf.
PfamiView protein in Pfam
PF00067. p450. 1 hit.
PRINTSiPR00463. EP450I.
PR00385. P450.
SUPFAMiSSF48264. SSF48264. 1 hit.
PROSITEiView protein in PROSITE
PS00086. CYTOCHROME_P450. 1 hit.

Sequencei

Sequence statusi: Complete.

Q27465-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPSLRNAILL TIATTFLYFR IMRTLNFDNY MATYIYFLTC ITLYAIYELN
60 70 80 90 100
YKRRRLPNGP VPWLVAGNMP SFINVNNVDV LFQSWKQQYG GIFTVWIGPI
110 120 130 140 150
PLVMVSDLPT IKKYFIQHAD SFSNRWRNFV TDSIMEGSNG IVQIDGNKWR
160 170 180 190 200
EQRRFALHTL RDFGVGKPLM EQMITLEVTS LMNHMEKSCG LDGKELHLCP
210 220 230 240 250
SIAVCVGNII NNMLFGLRFN QDNSYMHRLH QLLDDQSHTV MQPIMGAYIA
260 270 280 290 300
FPVTSKIPII NGEWNRLMGI KNELLEFLET QIEGHRMNWK DEMIEQEPED
310 320 330 340 350
LTYAYMIEVE KRKRNGEDVG FFDDQQLKML LLDLFFAGME TTVTTLKWAF
360 370 380 390 400
LLMAKNQKVQ KNVQAELDSI GQPMIEIQHR TRLPYVQATI NEIQRIANIL
410 420 430 440 450
PINLLRTVAE DIEIDGYNFK KGDLIIPQIS ILMNDPEIFE NPEEFNPSRF
460 470 480 490 500
LDEDNNVKKI DEFLPFSIGR RQCLGESLAR AELYLVFANL IQNFNFEVAD
510 520 530
DVTTERVLGL TVSPVEYSCK ITRRGLDHNQ NSVK
Length:534
Mass (Da):61,947
Last modified:June 1, 2001 - v2
Checksum:i8A3C99165F8EBE7A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284602 Genomic DNA. Translation: CCD61735.1.
RefSeqiNP_494797.1. NM_062396.4.
UniGeneiCel.16058.

Genome annotation databases

EnsemblMetazoaiB0304.3; B0304.3; WBGene00015135.
GeneIDi173787.
KEGGicel:CELE_B0304.3.
UCSCiB0304.3. c. elegans.

Similar proteinsi

Entry informationi

Entry nameiQ27465_CAEEL
AccessioniPrimary (citable) accession number: Q27465
Entry historyiIntegrated into UniProtKB/TrEMBL: November 1, 1996
Last sequence update: June 1, 2001
Last modified: November 22, 2017
This is version 136 of the entry and version 2 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported