Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Sodium/potassium-transporting ATPase subunit alpha

Gene

eat-6

Organism
Caenorhabditis elegans
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

GO - Molecular functioni

Keywordsi

Molecular functionHydrolaseUniRule annotationSAAS annotation
Biological processIon transport, Potassium transportUniRule annotation, Transport
LigandATP-bindingUniRule annotationSAAS annotation, Metal-bindingUniRule annotation, Nucleotide-binding, Potassium

Names & Taxonomyi

Protein namesi
Recommended name:
Sodium/potassium-transporting ATPase subunit alphaUniRule annotation (EC:3.6.3.-UniRule annotation)
Gene namesi
Name:eat-6Imported
OrganismiCaenorhabditis elegansImported
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei74 – 93HelicalUniRule annotationAdd BLAST20
Transmembranei108 – 127HelicalUniRule annotationAdd BLAST20
Transmembranei269 – 293HelicalUniRule annotationAdd BLAST25
Transmembranei299 – 322HelicalUniRule annotationAdd BLAST24
Transmembranei822 – 845HelicalUniRule annotationAdd BLAST24
Transmembranei886 – 905HelicalUniRule annotationAdd BLAST20
Transmembranei925 – 946HelicalUniRule annotationAdd BLAST22
Transmembranei958 – 974HelicalUniRule annotationAdd BLAST17

Keywords - Cellular componenti

Membrane

PTM / Processingi

Proteomic databases

PaxDbiQ27461.
PeptideAtlasiQ27461.

Expressioni

Gene expression databases

BgeeiWBGene00001137.
ExpressionAtlasiQ27461. baseline and differential.

Structurei

3D structure databases

ProteinModelPortaliQ27461.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini20 – 94Cation_ATPase_NInterPro annotationAdd BLAST75

Sequence similaritiesi

Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIC subfamily. [View classification]UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixUniRule annotationSAAS annotation

Phylogenomic databases

eggNOGiKOG0203. Eukaryota.
COG0474. LUCA.

Family and domain databases

CDDicd02608. P-type_ATPase_Na-K_like. 1 hit.
Gene3Di3.40.1110.10. 2 hits.
InterProiView protein in InterPro
IPR006068. ATPase_P-typ_cation-transptr_C.
IPR004014. ATPase_P-typ_cation-transptr_N.
IPR023299. ATPase_P-typ_cyto_dom_N.
IPR018303. ATPase_P-typ_P_site.
IPR023298. ATPase_P-typ_TM_dom_sf.
IPR008250. ATPase_P-typ_transduc_dom_A_sf.
IPR036412. HAD-like_sf.
IPR005775. P-type_ATPase_IIC.
IPR001757. P_typ_ATPase.
PfamiView protein in Pfam
PF00689. Cation_ATPase_C. 1 hit.
PF00690. Cation_ATPase_N. 1 hit.
SMARTiView protein in SMART
SM00831. Cation_ATPase_N. 1 hit.
SUPFAMiSSF56784. SSF56784. 1 hit.
SSF81653. SSF81653. 1 hit.
SSF81660. SSF81660. 1 hit.
SSF81665. SSF81665. 3 hits.
TIGRFAMsiTIGR01106. ATPase-IIC_X-K. 1 hit.
TIGR01494. ATPase_P-type. 2 hits.
PROSITEiView protein in PROSITE
PS00154. ATPASE_E1_E2. 1 hit.

Sequencei

Sequence statusi: Complete.

Q27461-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGKKDKKQEL HDLKQEVKMD EHIVPIEELV ARLGTNLETG LTRQKAQEVL
60 70 80 90 100
AKNGPNALSP PETTPEWIKF CKNLFGGFAM LLWVGAILCY IAYSVDYFTM
110 120 130 140 150
EYPSKDNLYL GIVLMTVVVI TGVFQYYQES KSSKIMDSFK NMVPTFALVH
160 170 180 190 200
RDGQKQQVKT EELVVGDIVE VKGGDRVPAD LRVVSAFGFK VDNSSLTGES
210 220 230 240 250
EPQSRSPDCT NENPLETRNI AFFSTNAVEG TAKGIVIYTG DNTVMGRIAH
260 270 280 290 300
LASGLDTGMT PIAREIEHFI HLITGVAVFL GISFFIIAFI LGYHWLTAVV
310 320 330 340 350
FLIGIIVANV PEGLIATVTV CLTLTAKRMA SKNCLVKNLE AVETLGSTST
360 370 380 390 400
ICSDKTGTLT QNRMTVAHMW YDETIHECDT TETQTSQEKR TGASFEALVR
410 420 430 440 450
IASLCNRAEF KAGQQDTPIL RRDCTGDASE IALLKFTELT QGNVIAVREK
460 470 480 490 500
NKKIAEIPFN STNKYQVSIH DNGDHYLLVM KGAPERILDV CSTIFLNGKE
510 520 530 540 550
SELTDKLRED FNTAYLELGG MGERVLGFCD FVLPADKFPK GFKFDVEEVN
560 570 580 590 600
FPLKNLRFVG LMSMIDPPRA AVPDAVAKCR SAGIKVVMVT GDHPITAKAI
610 620 630 640 650
AKSVGIISDG TETVEDIAIR RGIPVEEVNP REAKAAVIHG SDLREMSEDQ
660 670 680 690 700
LAEIIKYHSE IVFARTSPQQ KLMIVEGFQK QGQIVAVTGD GCNDSPALKK
710 720 730 740 750
ADIGVAMGIA GSDVSKQAAD MILLDDNFAS YVVGVEEGRL IFDNLKKSIA
760 770 780 790 800
YTLTSNIPEI SPFLTYILFG IPLPLGTVTI LCIDLGTDMV PAISLAYEEA
810 820 830 840 850
ESDIMKRQPR DPIRDKLVNE RLISLAYGQI GMIQASAGFF TYFWIMADNG
860 870 880 890 900
FMPWDLYQLR AQWDSRAYNN VLDSYGQEWT YANRKILEYT CQTAYFVSIV
910 920 930 940 950
VVQWADLIIS KTRRNSLVQQ GMSNWTLNFG LVFETALAWF MCYCPGLDNG
960 970 980 990
LRMYGLRFSW WFCALPFSIL IFVYDEIRRF LIRRYPGGWV ERETYY
Length:996
Mass (Da):111,057
Last modified:November 1, 1996 - v1
Checksum:i5C27189A83BBD16B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U18546 Genomic DNA. Translation: AAB02615.1.

Genome annotation databases

UCSCiB0365.3.1. c. elegans.

Similar proteinsi

Entry informationi

Entry nameiQ27461_CAEEL
AccessioniPrimary (citable) accession number: Q27461
Entry historyiIntegrated into UniProtKB/TrEMBL: November 1, 1996
Last sequence update: November 1, 1996
Last modified: November 22, 2017
This is version 118 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)