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Protein

Adhesive plaque matrix protein

Gene

FP1

Organism
Mytilus galloprovincialis (Mediterranean mussel)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

Provides adhesiveness to the mussel's foot. Mussels produce one of the strongest water insoluble glues. The mussel's adhesive is a bundle of threads, called a byssus, formed by a fibrous collagenous core coated with adhesive proteins.

Names & Taxonomyi

Protein namesi
Recommended name:
Adhesive plaque matrix protein
Alternative name(s):
Foot protein 1
MGFP-1
Short name:
MGFP1
Gene namesi
Name:FP1
OrganismiMytilus galloprovincialis (Mediterranean mussel)
Taxonomic identifieri29158 [NCBI]
Taxonomic lineageiEukaryotaMetazoaLophotrochozoaMolluscaBivalviaPteriomorphiaMytiloidaMytiloideaMytilidaeMytilinaeMytilus

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 20Sequence analysisAdd BLAST20
ChainiPRO_000002128621 – 751Adhesive plaque matrix proteinAdd BLAST731

Post-translational modificationi

Hydroxylated on proline (mono- or dihydroxylation) and tyrosine residues (to L-DOPA = 3',4'-dihydroxyphenylalanine) of the tandem repeats.By similarity

Keywords - PTMi

Hydroxylation

Expressioni

Tissue specificityi

Produced by the byssal gland.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Repeati109 – 118110
Repeati119 – 128210
Repeati129 – 138310
Repeati139 – 148410
Repeati149 – 158510
Repeati159 – 168610
Repeati169 – 178710
Repeati179 – 188810
Repeati189 – 198910
Repeati199 – 2081010
Repeati209 – 2181110
Repeati219 – 2281210
Repeati229 – 2381310
Repeati239 – 2481410
Repeati249 – 2581510
Repeati259 – 2681610
Repeati269 – 2781710
Repeati279 – 2881810
Repeati289 – 2981910
Repeati299 – 3082010
Repeati309 – 3182110
Repeati319 – 3282210
Repeati329 – 3382310
Repeati339 – 3482410
Repeati349 – 3582510
Repeati359 – 3682610
Repeati369 – 3782710
Repeati379 – 3882810
Repeati389 – 3982910
Repeati399 – 4083010
Repeati409 – 4183110
Repeati419 – 4283210
Repeati429 – 4383310
Repeati439 – 4483410
Repeati449 – 4583510
Repeati459 – 4683610
Repeati469 – 4783710
Repeati479 – 4883810
Repeati489 – 4983910
Repeati499 – 5084010
Repeati509 – 5184110
Repeati519 – 5284210
Repeati529 – 5384310
Repeati539 – 5484410
Repeati549 – 5584510
Repeati559 – 5684610
Repeati569 – 5784710
Repeati579 – 5884810
Repeati589 – 5984910
Repeati599 – 6085010
Repeati609 – 6185110
Repeati619 – 6285210
Repeati629 – 6385310
Repeati639 – 6485410
Repeati649 – 6585510
Repeati659 – 66256; truncated4
Repeati663 – 6725710
Repeati673 – 6825810
Repeati683 – 6925910
Repeati693 – 7026010
Repeati703 – 7126110
Repeati713 – 7226210
Repeati723 – 7326310

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni21 – 41Nonrepetitive linkerAdd BLAST21
Regioni109 – 73263 X 10 AA tandem repeats of Y-[KR]-[APTS]-K-[KPMSLTIVA]-[STR]-Y-[PLS]-[PASRQT]-[STI]Add BLAST624

Domaini

Almost exclusively composed of repeats of a decapeptide.

Keywords - Domaini

Repeat, Signal

Family and domain databases

InterProiIPR002964. Adhesive_plaq.
[Graphical view]
PRINTSiPR01216. ADHESIVEI.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q27409-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEGIKLNLCL LCIFTCDILG FSNGNIYNAH GSAYAGASAG AYKTLPNAYP
60 70 80 90 100
YGTKHGPVYK PVKTSYHPTN SYPPTYGSKT NYLPLAKKLS SYKPIKTTYN
110 120 130 140 150
AKTNYPPVYK PKMTYPPTYK PKPSYPPTYK PKPSYPATYK SKSSYPSSYK
160 170 180 190 200
PKKTYPPTYK PKLTYPPTYK PKPSYPPTYK PKPSYPATYK SKSSYPPSYK
210 220 230 240 250
TKKTYPSSYK PKKTYPSTYK PKVSYPPTYK SKKSYPPIYK TKASYPSSYK
260 270 280 290 300
PKKTYPSTYK PKISYPPTYK AKPSYPTSYR AKPSYPSTYK AKPSYPPTYK
310 320 330 340 350
AKPSYPPTYK AKPTYPSTYK AKPSYPPTYK AKPSYPPTYK AKPSYPPSYK
360 370 380 390 400
PKTTYPPSYK PKISYPPTYK AKPSYPPIYK AKPSYPPTYK AKPSYLPTYK
410 420 430 440 450
AKPSYPPTYK AKPRYPTTYK AKPSYPPTYK AKPSYPPTYK AKLSYPPTYK
460 470 480 490 500
AKPSYPPTYK AKPSYPPTYK AKPSYPPTYK TKPSYPRTYK AKPSYSSTYK
510 520 530 540 550
AKPSYPPTYK AKPSYPPTYK AKPSYPPTYK AKPSYPPTYK AKPSYPPTYK
560 570 580 590 600
AKPSYPQTYK AKSSYPPTYK AKPSYPPTYK AKPSYPPTYK AKPSYPPTYK
610 620 630 640 650
AKPSYPPTYK AKPSYPPTYK AKPSYPPTYK AKPSYPPTYK AKPSYPPTYK
660 670 680 690 700
AKPSYPATYP STYKAKPSYP PTYKAKPSYP PTYKPKPSYP PTYKSKSSYP
710 720 730 740 750
SSYKPKKTYP PTYKPKLTYP PIYKPKPSYP PTYKSSYPPR YKKKISYPSQ

Y
Length:751
Mass (Da):85,791
Last modified:November 1, 1996 - v1
Checksum:iE9E8D91C33C95C7D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
D63778 mRNA. Translation: BAA09851.1.
PIRiS68957.

Cross-referencesi

Web resourcesi

Protein Spotlight

Sticky business - Issue 2 of September 2001

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
D63778 mRNA. Translation: BAA09851.1.
PIRiS68957.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Family and domain databases

InterProiIPR002964. Adhesive_plaq.
[Graphical view]
PRINTSiPR01216. ADHESIVEI.
ProtoNetiSearch...

Entry informationi

Entry nameiFP1_MYTGA
AccessioniPrimary (citable) accession number: Q27409
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 30, 2000
Last sequence update: November 1, 1996
Last modified: January 7, 2015
This is version 63 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)

Miscellaneousi

Documents

  1. Protein Spotlight
    Protein Spotlight articles and cited UniProtKB/Swiss-Prot entries

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.