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Q27287 (MTB_STRPU) Reviewed, UniProtKB/Swiss-Prot

Last modified October 16, 2013. Version 54. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Metallothionein-B

Short name=MTB
Gene names
Name:MTB1
Synonyms:MTB
OrganismStrongylocentrotus purpuratus (Purple sea urchin) [Reference proteome]
Taxonomic identifier7668 [NCBI]
Taxonomic lineageEukaryotaMetazoaEchinodermataEleutherozoaEchinozoaEchinoideaEuechinoideaEchinaceaEchinoidaStrongylocentrotidaeStrongylocentrotus

Protein attributes

Sequence length65 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Function

Metallothioneins have a high content of cysteine residues that bind various heavy metals.

Induction

By heavy metals.

Sequence similarities

Belongs to the metallothionein superfamily. Type 4 family.

Ontologies

Keywords
   LigandMetal-binding
Metal-thiolate cluster
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Molecular_functionmetal ion binding

Inferred from electronic annotation. Source: UniProtKB-KW

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 6565Metallothionein-B
PRO_0000197348

Sequences

Sequence LengthMass (Da)Tools
Q27287 [UniParc].

Last modified November 1, 1996. Version 1.
Checksum: 12E1C8064D9121A5

FASTA656,470
        10         20         30         40         50         60 
MPDVKCVCCK EGNECACTGQ DCCTIGKCCK DGTCCGKCSN AACKTCADGC TCGSGCSCTE 


GNCPC 

« Hide

References

[1]"Metallothionein genes MTa and MTb expressed under distinct quantitative and tissue-specific regulation in sea urchin embryos."
Wilkinson D.G., Nemer M.
Mol. Cell. Biol. 7:48-58(1987) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [MRNA].
[2]"Structure, spatial, and temporal expression of two sea urchin metallothionein genes, SpMTB1 and SpMTA."
Nemer M., Thornton R.D., Stuebing E.W., Harlow P.
J. Biol. Chem. 266:6586-6593(1991) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
M15989 mRNA. Translation: AAA30063.1.
M59822 Genomic DNA. Translation: AAA30062.1.
PIRA38739.
RefSeqNP_999741.1. NM_214576.2.
UniGeneSpu.20128.

3D structure databases

ProteinModelPortalQ27287.
SMRQ27287. Positions 2-65.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING7668.Q27287.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID373378.
KEGGspu:373378.

Organism-specific databases

CTD373378.

Family and domain databases

InterProIPR017980. Metalthion_4_echinoid/annelid.
IPR001396. Metalthion_4_echinoidea.
IPR017854. Metalthion_dom.
[Graphical view]
PfamPF05522. Metallothio_6. 1 hit.
[Graphical view]
PRINTSPR00873. MTECHINOIDEA.
SUPFAMSSF57868. SSF57868. 2 hits.
ProtoNetSearch...

Entry information

Entry nameMTB_STRPU
AccessionPrimary (citable) accession number: Q27287
Entry history
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: November 1, 1996
Last modified: October 16, 2013
This is version 54 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)

Relevant documents

SIMILARITY comments

Index of protein domains and families

Metallothioneins

Classification of metallothioneins and list of entries