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Q27287

- MTB_STRPU

UniProt

Q27287 - MTB_STRPU

Protein

Metallothionein-B

Gene

MTB1

Organism
Strongylocentrotus purpuratus (Purple sea urchin)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli
  1. Functioni

    Metallothioneins have a high content of cysteine residues that bind various heavy metals.

    GO - Molecular functioni

    1. metal ion binding Source: UniProtKB-KW

    Keywords - Ligandi

    Metal-binding, Metal-thiolate cluster

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Metallothionein-B
    Short name:
    MTB
    Gene namesi
    Name:MTB1
    Synonyms:MTB
    OrganismiStrongylocentrotus purpuratus (Purple sea urchin)
    Taxonomic identifieri7668 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaEchinodermataEleutherozoaEchinozoaEchinoideaEuechinoideaEchinaceaEchinoidaStrongylocentrotidaeStrongylocentrotus
    ProteomesiUP000007110: Unplaced

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 6565Metallothionein-BPRO_0000197348Add
    BLAST

    Expressioni

    Inductioni

    By heavy metals.

    Interactioni

    Protein-protein interaction databases

    STRINGi7668.Q27287.

    Structurei

    3D structure databases

    ProteinModelPortaliQ27287.
    SMRiQ27287. Positions 2-65.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Family and domain databases

    InterProiIPR017980. Metalthion_4_echinoid/annelid.
    IPR001396. Metalthion_4_echinoidea.
    IPR017854. Metalthion_dom.
    [Graphical view]
    PfamiPF05522. Metallothio_6. 1 hit.
    [Graphical view]
    PRINTSiPR00873. MTECHINOIDEA.
    SUPFAMiSSF57868. SSF57868. 2 hits.

    Sequencei

    Sequence statusi: Complete.

    Q27287-1 [UniParc]FASTAAdd to Basket

    « Hide

    MPDVKCVCCK EGNECACTGQ DCCTIGKCCK DGTCCGKCSN AACKTCADGC   50
    TCGSGCSCTE GNCPC 65
    Length:65
    Mass (Da):6,470
    Last modified:November 1, 1996 - v1
    Checksum:i12E1C8064D9121A5
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    M15989 mRNA. Translation: AAA30063.1.
    M59822 Genomic DNA. Translation: AAA30062.1.
    PIRiA38739.
    RefSeqiNP_999741.1. NM_214576.2.
    UniGeneiSpu.20128.

    Genome annotation databases

    GeneIDi373378.
    KEGGispu:373378.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    M15989 mRNA. Translation: AAA30063.1 .
    M59822 Genomic DNA. Translation: AAA30062.1 .
    PIRi A38739.
    RefSeqi NP_999741.1. NM_214576.2.
    UniGenei Spu.20128.

    3D structure databases

    ProteinModelPortali Q27287.
    SMRi Q27287. Positions 2-65.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 7668.Q27287.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    GeneIDi 373378.
    KEGGi spu:373378.

    Organism-specific databases

    CTDi 373378.

    Family and domain databases

    InterProi IPR017980. Metalthion_4_echinoid/annelid.
    IPR001396. Metalthion_4_echinoidea.
    IPR017854. Metalthion_dom.
    [Graphical view ]
    Pfami PF05522. Metallothio_6. 1 hit.
    [Graphical view ]
    PRINTSi PR00873. MTECHINOIDEA.
    SUPFAMi SSF57868. SSF57868. 2 hits.
    ProtoNeti Search...

    Publicationsi

    1. "Metallothionein genes MTa and MTb expressed under distinct quantitative and tissue-specific regulation in sea urchin embryos."
      Wilkinson D.G., Nemer M.
      Mol. Cell. Biol. 7:48-58(1987) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [MRNA].
    2. "Structure, spatial, and temporal expression of two sea urchin metallothionein genes, SpMTB1 and SpMTA."
      Nemer M., Thornton R.D., Stuebing E.W., Harlow P.
      J. Biol. Chem. 266:6586-6593(1991) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].

    Entry informationi

    Entry nameiMTB_STRPU
    AccessioniPrimary (citable) accession number: Q27287
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: November 1, 1997
    Last sequence update: November 1, 1996
    Last modified: October 1, 2014
    This is version 55 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Metallothioneins
      Classification of metallothioneins and list of entries
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3