Q27287 (MTB_STRPU) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Metallothionein-B
Short name=MTB

Gene names

Name:	MTB1
Synonyms:	MTB

Organism

Strongylocentrotus purpuratus (Purple sea urchin) [Reference proteome]

Taxonomic identifier

7668 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Echinodermata › Eleutherozoa › Echinozoa › Echinoidea › Euechinoidea › Echinacea › Echinoida › Strongylocentrotidae › Strongylocentrotus

Protein attributes

Sequence length	65 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Function	Metallothioneins have a high content of cysteine residues that bind various heavy metals.
Induction	By heavy metals.
Sequence similarities	Belongs to the metallothionein superfamily. Type 4 family.

Ontologies

Keywords
Ligand	Metal-binding Metal-thiolate cluster
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Molecular_function	metal ion binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 65	65	Metallothionein-B		PRO_0000197348

Sequences

	Sequence		Length	Mass (Da)
	Q27287 [UniParc]. Last modified November 1, 1996. Version 1. Checksum: 12E1C8064D9121A5	FASTA	65	6,470
	10 20 30 40 50 60 MPDVKCVCCK EGNECACTGQ DCCTIGKCCK DGTCCGKCSN AACKTCADGC TCGSGCSCTE GNCPC

References

[1]	"Metallothionein genes MTa and MTb expressed under distinct quantitative and tissue-specific regulation in sea urchin embryos." Wilkinson D.G., Nemer M. Mol. Cell. Biol. 7:48-58(1987) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA].
[2]	"Structure, spatial, and temporal expression of two sea urchin metallothionein genes, SpMTB1 and SpMTA." Nemer M., Thornton R.D., Stuebing E.W., Harlow P. J. Biol. Chem. 266:6586-6593(1991) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	M15989 mRNA. Translation: AAA30063.1. M59822 Genomic DNA. Translation: AAA30062.1.
PIR	A38739.
RefSeq	NP_999741.1. NM_214576.2.
UniGene	Spu.20128.
3D structure databases
ProteinModelPortal	Q27287.
SMR	Q27287. Positions 2-65.
ModBase	Search...
Protein-protein interaction databases
STRING	7668.Q27287.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	373378.
KEGG	spu:373378.
Organism-specific databases
CTD	373378.
Family and domain databases
InterPro	IPR017980. Metalthion_4_echinoid/annelid. IPR001396. Metalthion_4_echinoidea. IPR017854. Metalthion_dom. [Graphical view]
Pfam	PF05522. Metallothionein. 1 hit. [Graphical view]
PRINTS	PR00873. MTECHINOIDEA.
SUPFAM	SSF57868. Metallothionein_sfam. 2 hits.
ProtoNet	Search...

Entry information

Entry name

MTB_STRPU

Accession

Primary (citable) accession number: Q27287

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 1, 1997
Last sequence update:	November 1, 1996
Last modified:	April 3, 2013
This is version 52 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)