Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Q27181

- T2C_PARTE

UniProt

Q27181 - T2C_PARTE

Protein

Trichocyst matrix protein T2-C

Gene

T2C

Organism
Paramecium tetraurelia
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at protein leveli
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 64 (01 Oct 2014)
      Sequence version 1 (01 Nov 1996)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Structural protein that crystallize inside the trichocyst matrix.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Trichocyst matrix protein T2-C
    Alternative name(s):
    Secretory granule protein T2-C
    TMP 2-C
    Cleaved into the following 2 chains:
    Gene namesi
    Name:T2C
    ORF Names:GSPATT00003811001
    OrganismiParamecium tetraurelia
    Taxonomic identifieri5888 [NCBI]
    Taxonomic lineageiEukaryotaAlveolataCiliophoraIntramacronucleataOligohymenophoreaPeniculidaParameciidaeParamecium
    ProteomesiUP000000600: Partially assembled WGS sequence

    Subcellular locationi

    Trichocyst
    Note: These are architecturally complex secretory storage granules-docked at the plasma membrane, ready to rapidly respond to an exocytotic stimulus.

    GO - Cellular componenti

    1. trichocyst Source: UniProtKB-SubCell

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Signal peptidei1 – 1919Sequence AnalysisAdd
    BLAST
    Propeptidei20 – 4829PRO_0000034381Add
    BLAST
    Chaini49 – 183135Trichocyst matrix protein T2-C 1PRO_0000034382Add
    BLAST
    Propeptidei184 – 23956PRO_0000034383Add
    BLAST
    Chaini240 – 387148Trichocyst matrix protein T2-C 2PRO_0000034384Add
    BLAST

    Post-translational modificationi

    Two components are produced by post-translational processing from the precursor peptide.

    Family & Domainsi

    Coiled coil

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Coiled coili51 – 163113Sequence AnalysisAdd
    BLAST
    Coiled coili294 – 33340Sequence AnalysisAdd
    BLAST

    Sequence similaritiesi

    Belongs to the TMP family.Curated

    Keywords - Domaini

    Coiled coil, Signal

    Sequencei

    Sequence statusi: Complete.

    Sequence processingi: The displayed sequence is further processed into a mature form.

    Q27181-1 [UniParc]FASTAAdd to Basket

    « Hide

    MKTIILALAL IVLASSTQAD VIATIKKIDQ SPFGRTLFDT IWLELQTGDP    50
    LDRLLQTLTD LEDRYVAEQK EDDARNHEYQ DACTVDIKAF DKDLAESNRK 100
    KIELEARLEG QLYPQRGILQ GLVAQKQAEV KGYQKDLDEL DAQRAEEKAD 150
    FEEKVLEHQE ATAIIAEARR LFADNIEHES FIQKGKATKQ PAHKFTKEVA 200
    SMIQKHFTTS AKKAAKFQHR KGYSKLFKAF ATIASKVEQL ADAGAVSKII 250
    DLADELLAKI ADSLSLLRFA EDKRVEAYKK SRNFIVISLT VAGTALANAQ 300
    SDLAALNDVI AQVEASLDTT NQRIENVSAD RNDRFTQCEE AVQDYQDARS 350
    ARSSDRDVVS QTIGLVNKEL RTLREQLALR QSAGEEI 387
    Length:387
    Mass (Da):43,312
    Last modified:November 1, 1996 - v1
    Checksum:iD6885D7E22EED1D8
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    U47116 Genomic DNA. Translation: AAC47028.1.
    CT868660 Genomic DNA. Translation: CAK90946.1.
    U27511 Genomic DNA. Translation: AAA92611.1.
    RefSeqiXP_001458343.1. XM_001458306.1.
    UniGeneiPte.18177.

    Genome annotation databases

    EnsemblProtistsiCAK90946; CAK90946; GSPATT00003811001.
    GeneIDi5044128.
    KEGGiptm:GSPATT00003811001.

    Cross-referencesi

    Web resourcesi

    Protein Spotlight

    The arsenal of Paramecium - Issue 3 of October 2000

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    U47116 Genomic DNA. Translation: AAC47028.1 .
    CT868660 Genomic DNA. Translation: CAK90946.1 .
    U27511 Genomic DNA. Translation: AAA92611.1 .
    RefSeqi XP_001458343.1. XM_001458306.1.
    UniGenei Pte.18177.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblProtistsi CAK90946 ; CAK90946 ; GSPATT00003811001 .
    GeneIDi 5044128.
    KEGGi ptm:GSPATT00003811001.

    Family and domain databases

    ProtoNeti Search...

    Publicationsi

    1. "Cloning and sequence analysis of genes coding for paramecium secretory granule (trichocyst) proteins. A unique protein fold for a family of polypeptides with different primary structures."
      Gautier M.-C., Sperling L., Madeddu L.
      J. Biol. Chem. 271:10247-10255(1996) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
      Strain: Stock d4-2.
    2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: Stock d4-2.
    3. "A large multigene family codes for the polypeptides of the crystalline trichocyst matrix in Paramecium."
      Madeddu L., Gautier M.-C., Vayssie L., Houari A., Sperling L.
      Mol. Biol. Cell 6:649-659(1995) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 49-72.
      Strain: Stock d4-2.
    4. "Protein processing and morphogenesis of secretory granules in Paramecium."
      Madeddu L., Gautier M.-C., le Caer J.-P., de Loubresse N., Sperling L.
      Biochimie 76:329-335(1994) [PubMed] [Europe PMC] [Abstract]
      Cited for: PARTIAL PROTEIN SEQUENCE.
      Strain: Stock d4-2.

    Entry informationi

    Entry nameiT2C_PARTE
    AccessioniPrimary (citable) accession number: Q27181
    Secondary accession number(s): A0E6M9, Q27175
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: July 15, 1999
    Last sequence update: November 1, 1996
    Last modified: October 1, 2014
    This is version 64 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Direct protein sequencing, Reference proteome

    Documents

    1. Protein Spotlight
      Protein Spotlight articles and cited UniProtKB/Swiss-Prot entries
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3