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Q27180

- T1B_PARTE

UniProt

Q27180 - T1B_PARTE

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Protein

Trichocyst matrix protein T1-B

Gene

T1B

Organism
Paramecium tetraurelia
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at protein leveli

Functioni

Structural protein that crystallize inside the trichocyst matrix.

Names & Taxonomyi

Protein namesi
Recommended name:
Trichocyst matrix protein T1-B
Alternative name(s):
Secretory granule protein T1-B
TMP 1-B
Cleaved into the following 2 chains:
Gene namesi
Name:T1B
ORF Names:GSPATT00027326001
OrganismiParamecium tetraurelia
Taxonomic identifieri5888 [NCBI]
Taxonomic lineageiEukaryotaAlveolataCiliophoraIntramacronucleataOligohymenophoreaPeniculidaParameciidaeParamecium
ProteomesiUP000000600: Partially assembled WGS sequence

Subcellular locationi

Trichocyst
Note: These are architecturally complex secretory storage granules-docked at the plasma membrane, ready to rapidly respond to an exocytotic stimulus.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 1616Sequence AnalysisAdd
BLAST
Propeptidei17 – 5539PRO_0000034377Add
BLAST
Chaini56 – 189134Trichocyst matrix protein T1-B 1PRO_0000034378Add
BLAST
Propeptidei190 – 22536PRO_0000034379Add
BLAST
Chaini226 – 369144Trichocyst matrix protein T1-B 2PRO_0000034380Add
BLAST

Post-translational modificationi

Two components are produced by post-translational processing from the precursor peptide.

Family & Domainsi

Coiled coil

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Coiled coili56 – 180125Sequence AnalysisAdd
BLAST
Coiled coili262 – 35493Sequence AnalysisAdd
BLAST

Sequence similaritiesi

Belongs to the TMP family.Curated

Keywords - Domaini

Coiled coil, Signal

Phylogenomic databases

InParanoidiQ27180.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q27180-1 [UniParc]FASTAAdd to Basket

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        10         20         30         40         50
MYKLAVCTLL ILSVTAIDVT NSVWTSHDQK AFAQIKQSGW GNFILNFGEL
60 70 80 90 100
HLQTGGILAE LNTEIAKLID ELDEELAEVH HQYARRTDVH NREVSRLEQE
110 120 130 140 150
IQDKEREVFN AHDFYDNVLI PQRDRFAAQL EQLQENIAQN RRTLNEATVQ
160 170 180 190 200
RANDHAEFES QVAEHNEAIS AIDESLQLLS QLESPSLVQI QKVQKNLTKI
210 220 230 240 250
QQSLKRHSTF QTFIKTLLEI AVEANFADQG ALREILTAFN NLRVQLVDSL
260 270 280 290 300
NQLTADEAEA QKDFEARVIQ LNQEHAEFQR AVVVKTAEIE ANANKIEQTL
310 320 330 340 350
DLIDVLHADL DTLNGQLQAE NDDYAFATDV YNATVSEYNK ELNAAHQALD
360
LLNQPRFTDY VKSQLKGAF
Length:369
Mass (Da):41,963
Last modified:November 1, 1996 - v1
Checksum:i82CFD93E424BA3AD
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U47115 Genomic DNA. Translation: AAC47027.1.
CT868680 Genomic DNA. Translation: CAK94998.1.
U27504 Genomic DNA. Translation: AAA92604.1.
RefSeqiXP_001462371.1. XM_001462334.1.
UniGeneiPte.28170.

Genome annotation databases

EnsemblProtistsiCAK94998; CAK94998; GSPATT00027326001.
GeneIDi5048156.
KEGGiptm:GSPATT00027326001.

Cross-referencesi

Web resourcesi

Protein Spotlight

The arsenal of Paramecium - Issue 3 of October 2000

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U47115 Genomic DNA. Translation: AAC47027.1 .
CT868680 Genomic DNA. Translation: CAK94998.1 .
U27504 Genomic DNA. Translation: AAA92604.1 .
RefSeqi XP_001462371.1. XM_001462334.1.
UniGenei Pte.28170.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblProtistsi CAK94998 ; CAK94998 ; GSPATT00027326001 .
GeneIDi 5048156.
KEGGi ptm:GSPATT00027326001.

Phylogenomic databases

InParanoidi Q27180.

Family and domain databases

ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Cloning and sequence analysis of genes coding for paramecium secretory granule (trichocyst) proteins. A unique protein fold for a family of polypeptides with different primary structures."
    Gautier M.-C., Sperling L., Madeddu L.
    J. Biol. Chem. 271:10247-10255(1996) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: Stock d4-2.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Stock d4-2.
  3. "A large multigene family codes for the polypeptides of the crystalline trichocyst matrix in Paramecium."
    Madeddu L., Gautier M.-C., Vayssie L., Houari A., Sperling L.
    Mol. Biol. Cell 6:649-659(1995) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 226-259.
    Strain: Stock d4-2.
  4. "Protein processing and morphogenesis of secretory granules in Paramecium."
    Madeddu L., Gautier M.-C., le Caer J.-P., de Loubresse N., Sperling L.
    Biochimie 76:329-335(1994) [PubMed] [Europe PMC] [Abstract]
    Cited for: PARTIAL PROTEIN SEQUENCE.
    Strain: Stock d4-2.

Entry informationi

Entry nameiT1B_PARTE
AccessioniPrimary (citable) accession number: Q27180
Secondary accession number(s): A0EI57, Q27247
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 15, 1999
Last sequence update: November 1, 1996
Last modified: October 29, 2014
This is version 65 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. Protein Spotlight
    Protein Spotlight articles and cited UniProtKB/Swiss-Prot entries
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3