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Protein
Submitted name:

Cruzipain

Gene
N/A
Organism
Trypanosoma cruzi
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein inferred from homologyi

Functioni

GO - Molecular functioni

Keywordsi

Molecular functionHydrolase, Protease, Thiol proteaseSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
CruzipainImported
OrganismiTrypanosoma cruziImported
Taxonomic identifieri5693 [NCBI]
Taxonomic lineageiEukaryotaEuglenozoaKinetoplastidaTrypanosomatidaeTrypanosomaSchizotrypanum

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 26UniRule annotationAdd BLAST26
ChainiPRO_500540017127 – 467UniRule annotationAdd BLAST441

Proteomic databases

PaxDbiQ26884.

Structurei

3D structure databases

ProteinModelPortaliQ26884.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini38 – 94Inhibitor_I29InterPro annotationAdd BLAST57
Domaini123 – 335Pept_C1InterPro annotationAdd BLAST213

Sequence similaritiesi

Belongs to the peptidase C1 family.UniRule annotationSAAS annotation

Keywords - Domaini

SignalUniRule annotation

Phylogenomic databases

eggNOGiKOG1542. Eukaryota.
COG4870. LUCA.

Family and domain databases

InterProiView protein in InterPro
IPR021981. DUF3586.
IPR025661. Pept_asp_AS.
IPR000169. Pept_cys_AS.
IPR025660. Pept_his_AS.
IPR013128. Peptidase_C1A.
IPR000668. Peptidase_C1A_C.
IPR013201. Prot_inhib_I29.
PANTHERiPTHR12411. PTHR12411. 1 hit.
PfamiView protein in Pfam
PF12131. DUF3586. 1 hit.
PF08246. Inhibitor_I29. 1 hit.
PF00112. Peptidase_C1. 1 hit.
PRINTSiPR00705. PAPAIN.
SMARTiView protein in SMART
SM00848. Inhibitor_I29. 1 hit.
SM00645. Pept_C1. 1 hit.
PROSITEiView protein in PROSITE
PS00640. THIOL_PROTEASE_ASN. 1 hit.
PS00139. THIOL_PROTEASE_CYS. 1 hit.
PS00639. THIOL_PROTEASE_HIS. 1 hit.

Sequencei

Sequence statusi: Complete.

Q26884-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSGWARALSL AAVLVVMACL VPAATASLHA EETLASQFAE FKQKHGRVYG
60 70 80 90 100
SAAEEAFRLS VFRENLFLAR LHAAANPHAT FGVTAFSDLT REEFRSRYHN
110 120 130 140 150
GAAHFAAAQE RARVPVNVEV VGAPAAVDWR ARGAVTAVKD QGQCGSCWAF
160 170 180 190 200
SAIGNVECQW FLAGHPLTNL SEQMLVSCDK TDSGCGGGLM NNAFEWIVQE
210 220 230 240 250
NNGAVYTEDS YPYASGEGIS PPCTTSGHTV GATITGHVEL PQDEAQIAAW
260 270 280 290 300
LAVNGPVAVA VDASSWMTYT GGVMTSCVSE QLDHGVLLVG YNDSAAVPYW
310 320 330 340 350
VIKNSWTTQW GEDGYIRIAK GSNQCLVKEE ASSAVVGGPG PTPEPTTTTT
360 370 380 390 400
TSAPGPSPSY FVQMSCTDAA CIVGCENVTL PTGQCLLTTS GVSAIVTCGA
410 420 430 440 450
ETLTEEVFLT STHCSGPSVR SSVPLNKCNR LLRGSVEFFC GSSSSGRLAD
460
VDRQRRYQPY HSRHRRL
Length:467
Mass (Da):49,636
Last modified:November 1, 1996 - v1
Checksum:i4093E67B1B433470
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U41454 Genomic DNA. Translation: AAB41119.1.
PIRiA44938.
A45629.

Similar proteinsi

Entry informationi

Entry nameiQ26884_TRYCR
AccessioniPrimary (citable) accession number: Q26884
Entry historyiIntegrated into UniProtKB/TrEMBL: November 1, 1996
Last sequence update: November 1, 1996
Last modified: October 25, 2017
This is version 78 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)