Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

cAMP-dependent protein kinase type II regulatory subunit

Gene
N/A
Organism
Strongylocentrotus purpuratus (Purple sea urchin)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei186cAMP 1By similarity1
Binding sitei195cAMP 1By similarity1
Binding sitei313cAMP 2By similarity1
Binding sitei322cAMP 2By similarity1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi121 – 238cAMP 1Add BLAST118
Nucleotide bindingi239 – 365cAMP 2Add BLAST127

GO - Molecular functioni

Keywordsi

LigandcAMP, cAMP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
cAMP-dependent protein kinase type II regulatory subunit
OrganismiStrongylocentrotus purpuratus (Purple sea urchin)
Taxonomic identifieri7668 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEchinodermataEleutherozoaEchinozoaEchinoideaEuechinoideaEchinaceaEchinoidaStrongylocentrotidaeStrongylocentrotus
Proteomesi
  • UP000007110 Componenti: Unassembled WGS sequence

Subcellular locationi

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002053981 – 369cAMP-dependent protein kinase type II regulatory subunitAdd BLAST369

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei81PhosphoserineBy similarity1

Keywords - PTMi

Phosphoprotein

Proteomic databases

PRIDEiQ26619

Interactioni

Subunit structurei

Tetramer, composed of 2 regulatory (R) and 2 catalytic (C) subunits. In the presence of cAMP it dissociates into 2 active monomeric C subunits and an R dimer (By similarity).By similarity

Protein-protein interaction databases

STRINGi7668.SPU_018419tr

Structurei

3D structure databases

ProteinModelPortaliQ26619
SMRiQ26619
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni1 – 120Dimerization and phosphorylationBy similarityAdd BLAST120

Sequence similaritiesi

Keywords - Domaini

Repeat

Phylogenomic databases

eggNOGiKOG1113 Eukaryota
COG0664 LUCA
KOiK04739

Family and domain databases

CDDicd00038 CAP_ED, 2 hits
Gene3Di2.60.120.10, 2 hits
InterProiView protein in InterPro
IPR012198 cAMP_dep_PK_reg_su
IPR003117 cAMP_dep_PK_reg_su_I/II_a/b
IPR018490 cNMP-bd-like
IPR018488 cNMP-bd_CS
IPR000595 cNMP-bd_dom
IPR014710 RmlC-like_jellyroll
PfamiView protein in Pfam
PF00027 cNMP_binding, 2 hits
PF02197 RIIa, 1 hit
PIRSFiPIRSF000548 PK_regulatory, 1 hit
SMARTiView protein in SMART
SM00100 cNMP, 2 hits
SM00394 RIIa, 1 hit
SUPFAMiSSF51206 SSF51206, 2 hits
PROSITEiView protein in PROSITE
PS00888 CNMP_BINDING_1, 1 hit
PS00889 CNMP_BINDING_2, 2 hits
PS50042 CNMP_BINDING_3, 2 hits

Sequencei

Sequence statusi: Complete.

Q26619-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNFEIPEGLT DLLQDFTVAV LREKPSDLVE FASSYFAKLQ ENNISLGGKR
60 70 80 90 100
GVTFTAPEDA ESDIDDEPPE LPKNRYARRK SVCAEKYDPE ADNDTDTQKL
110 120 130 140 150
VYPKSDEQRA RLTEAVKNIL LFRALDEKQM QEVIDAMFEK KTTPGDHVID
160 170 180 190 200
QGDDGDNFYV IDRGEYDIFV NDNKVGAYKD SGSFGELALM YNTPRAATIA
210 220 230 240 250
ATTDGILWAL DRVSFRRIVL KNAAKKRRIY EELLEKVSIF KSLEPYERMN
260 270 280 290 300
LADALVTRTY EDGDCIIAQG DGADGCYFIE AGQCRIAMKS ERSDNPDEEK
310 320 330 340 350
EVAIYNQGQY FGELALLTNK PRAASVYAVE DVDCLLDVNA FERLLGPCMD
360
IMKRNIEHYE QETSRLFGK
Length:369
Mass (Da):41,789
Last modified:November 1, 1996 - v1
Checksum:i30FCECC13D8C26A5
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U19887 mRNA Translation: AAA61966.1
RefSeqiNP_999688.1, NM_214523.1
UniGeneiSpu.2225

Genome annotation databases

GeneIDi373288
KEGGispu:373288

Similar proteinsi

Entry informationi

Entry nameiKAPR_STRPU
AccessioniPrimary (citable) accession number: Q26619
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 30, 2000
Last sequence update: November 1, 1996
Last modified: May 23, 2018
This is version 83 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Cookie policy

We would like to use anonymized google analytics cookies to gather statistics on how uniprot.org is used in aggregate. Learn more

UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health