Q26496 (MTB_SPHGR) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names	Recommended name: Metallothionein-B Short name=MTB
Organism	Sphaerechinus granularis (Purple sea urchin)
Taxonomic identifier	39374 [NCBI]
Taxonomic lineage	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Echinodermata › Eleutherozoa › Echinozoa › Echinoidea › Euechinoidea › Echinacea › Temnopleuroida › Toxopneustidae › Sphaerechinus

Protein attributes

Sequence length	67 AA.
Sequence status	Fragment.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Metallothioneins have a high content of cysteine residues that bind various heavy metals.
Sequence similarities	Belongs to the metallothionein superfamily. Type 4 family.

Ontologies

Keywords
Ligand	Metal-binding Metal-thiolate cluster
Gene Ontology (GO)
Molecular_function	metal ion binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	‹1 – 67	›67	Metallothionein-B		PRO_0000197350
Experimental info
	Non-terminal residue	1	1

Sequences

	Sequence		Length	Mass (Da)
	Q26496 [UniParc]. Last modified November 1, 1996. Version 1. Checksum: 468244876C5C565F	FASTA	67	6,576
	10 20 30 40 50 60 PGPDVKCVCC QDGEECPCKG GECCITGTCC KEGDGLCCGK CSNAACKCAD GCKCGSGCSC TLGNCTC

References

[1]

"PCR amplification and cloning of metallothionein complementary DNAs in temperate and Antarctic sea urchin characterized by a large difference in egg metallothionein content." Scudiero R., Capasso C., Carginale V., Riggio M., Capasso A., Ciaramella M., Filosa S., Parisi E. Cell. Mol. Life Sci. 53:472-477(1997) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA]. Tissue: Egg.

Cross-references

Sequence databases
EMBL GenBank DDBJ	Z67877 mRNA. Translation: CAA91784.1.
3D structure databases
ProteinModelPortal	Q26496.
SMR	Q26496. Positions 3-39, 41-67.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Family and domain databases
InterPro	IPR017980. Metalthion_4_echinoid/annelid. IPR001396. Metalthion_4_echinoidea. IPR017854. Metalthion_dom. [Graphical view]
Pfam	PF05522. Metallothionein. 1 hit. [Graphical view]
PRINTS	PR00873. MTECHINOIDEA.
SUPFAM	SSF57868. Metallothionein_sfam. 2 hits.
ProtoNet	Search...

Entry information

Entry name

MTB_SPHGR

Accession

Primary (citable) accession number: Q26496

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 1, 1997
Last sequence update:	November 1, 1996
Last modified:	April 3, 2013
This is version 46 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)