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Protein

Pilosulin-3a

Gene
N/A
Organism
Myrmecia pilosula (Jack jumper ant) (Australian jumper ant)
Status
Reviewed-Annotation score: Annotation score: 4 out of 5-Experimental evidence at protein leveli

Functioni

Has no hemolytic activity.

Names & Taxonomyi

Protein namesi
Recommended name:
Pilosulin-3a
Alternative name(s):
Allergen Myr p II
Pilosulin-2
Allergen: Myr p 2
OrganismiMyrmecia pilosula (Jack jumper ant) (Australian jumper ant)
Taxonomic identifieri13618 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaHymenopteraApocritaAculeataVespoideaFormicidaeMyrmeciinaeMyrmeciiniMyrmecia

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

Secreted

Pathology & Biotechi

Allergenic propertiesi

Causes an allergic reaction in human. Binds to IgE.

Keywords - Diseasei

Allergen

Protein family/group databases

Allergomei3381. Myr p 2.0101.
3575. Myr p 2.0102.
481. Myr p 2.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 26Sequence analysisAdd BLAST26
PropeptideiPRO_000003516427 – 481 PublicationAdd BLAST22
PeptideiPRO_000003516549 – 74Pilosulin-3aAdd BLAST26

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Disulfide bondi64Interchain (with C-17 in pilosulin 3b)
Disulfide bondi71Interchain (with C-10 in pilosulin 3b)
Modified residuei74Leucine amide1 Publication1

Keywords - PTMi

Amidation, Disulfide bond

Expressioni

Tissue specificityi

Expressed by the venom gland.

Interactioni

Subunit structurei

Heterodimer with pilosin-3b (AC P0C023); disulfide-linked. This heterodimer is named pilosulin-3.2 Publications

Family & Domainsi

Sequence similaritiesi

Belongs to the pilosulin family.Curated

Keywords - Domaini

Signal

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q26464-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKLSCLLLTL AIIFVLTIVH APNVEAKALA DPESDAVGFA DAVGEADPID
60 70
WKKVDWKKVS KKTCKVMLKA CKFLG
Length:75
Mass (Da):8,145
Last modified:November 1, 1997 - v1
Checksum:i4FFE49969405F7AC
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
S81785 mRNA. Translation: AAB36316.1.
PIRiS65711.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiMYR3A_MYRPI
AccessioniPrimary (citable) accession number: Q26464
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: November 1, 1997
Last modified: April 12, 2017
This is version 60 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)

Miscellaneousi

Keywords - Technical termi

Direct protein sequencing

Documents

  1. Allergens
    Nomenclature of allergens and list of entries
  2. SIMILARITY comments
    Index of protein domains and families