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Q26456

- ALL7_DERFA

UniProt

Q26456 - ALL7_DERFA

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Protein

Mite allergen Der f 7

Gene

DERF7

Organism
Dermatophagoides farinae (American house dust mite)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Recommended name:
Mite allergen Der f 7
Alternative name(s):
Allergen Der f VII
Allergen: Der f 7
Gene namesi
Name:DERF7
OrganismiDermatophagoides farinae (American house dust mite)
Taxonomic identifieri6954 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaChelicerataArachnidaAcariAcariformesSarcoptiformesAstigmataPsoroptidiaAnalgoideaPyroglyphidaeDermatophagoidinaeDermatophagoides

Subcellular locationi

GO - Cellular componenti

  1. extracellular region Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Secreted

Pathology & Biotechi

Allergenic propertiesi

Causes an allergic reaction in human. Common symptoms of mite allergy are bronchial asthma, allergic rhinitis and conjunctivitis.

Keywords - Diseasei

Allergen

Protein family/group databases

Allergomei307. Der f 7.
3256. Der f 7.0101.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 1717Sequence AnalysisAdd
BLAST
Chaini18 – 213196Mite allergen Der f 7PRO_0000001184Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Glycosylationi151 – 1511N-linked (GlcNAc...)Sequence Analysis

Keywords - PTMi

Glycoprotein

Proteomic databases

PRIDEiQ26456.

Structurei

Secondary structure

1
213
Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Helixi24 – 4118
Beta strandi43 – 519
Beta strandi54 – 618
Beta strandi63 – 7917
Helixi81 – 833
Beta strandi84 – 896
Beta strandi91 – 955
Beta strandi98 – 11013
Beta strandi112 – 12211
Beta strandi128 – 1369
Beta strandi139 – 15012
Beta strandi153 – 1597
Beta strandi163 – 1697
Helixi177 – 21135

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
3UV1X-ray2.00A/B18-213[»]
ProteinModelPortaliQ26456.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the mite group 7 allergen family.Curated

Keywords - Domaini

Signal

Family and domain databases

InterProiIPR020234. Mite_allergen_group-7.
[Graphical view]
ProDomiPD037435. Mite_group-7_allergen. 1 hit.
[Graphical view] [Entries sharing at least one domain]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q26456-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MMKFLLIAAV AFVAVSADPI HYDKITEEIN KAIDDAIAAI EQSETIDPMK
60 70 80 90 100
VPDHADKFER HVGIVDFKGE LAMRNIEARG LKQMKRQGDA NVKGEEGIVK
110 120 130 140 150
AHLLIGVHDD IVSMEYDLAY KLGDLHPTTH VISDIQDFVV ALSLEISDEG
160 170 180 190 200
NITMTSFEVR QFANVVNHIG GLSILDPIFG VLSDVLTAIF QDTVRKEMTK
210
VLAPAFKREL EKN
Length:213
Mass (Da):23,627
Last modified:November 1, 1997 - v1
Checksum:i3CF1F529107B7808
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
S80655 mRNA. Translation: AAB35977.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
S80655 mRNA. Translation: AAB35977.1 .

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
Entry Method Resolution (Å) Chain Positions PDBsum
3UV1 X-ray 2.00 A/B 18-213 [» ]
ProteinModelPortali Q26456.
ModBasei Search...
MobiDBi Search...

Protein family/group databases

Allergomei 307. Der f 7.
3256. Der f 7.0101.

Proteomic databases

PRIDEi Q26456.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Family and domain databases

InterProi IPR020234. Mite_allergen_group-7.
[Graphical view ]
ProDomi PD037435. Mite_group-7_allergen. 1 hit.
[Graphical view ] [Entries sharing at least one domain ]
ProtoNeti Search...

Publicationsi

  1. "Molecular cloning and immunological characterization of the house dust mite allergen Der f 7."
    Shen H.-D., Chua K.-Y., Lin W.L., Hsieh K.-H., Thomas W.R.
    Clin. Exp. Allergy 25:1000-1006(1995) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA].

Entry informationi

Entry nameiALL7_DERFA
AccessioniPrimary (citable) accession number: Q26456
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: November 1, 1997
Last modified: October 29, 2014
This is version 47 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)

Miscellaneousi

Keywords - Technical termi

3D-structure

Documents

  1. Allergens
    Nomenclature of allergens and list of entries
  2. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  3. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3