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Q26456

- ALL7_DERFA

UniProt

Q26456 - ALL7_DERFA

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Protein
Mite allergen Der f 7
Gene
DERF7
Organism
Dermatophagoides farinae (American house dust mite)
Status
Reviewed - Annotation score: 2 out of 5 - Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Recommended name:
Mite allergen Der f 7
Alternative name(s):
Allergen Der f VII
Allergen: Der f 7
Gene namesi
Name:DERF7
OrganismiDermatophagoides farinae (American house dust mite)
Taxonomic identifieri6954 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaChelicerataArachnidaAcariAcariformesSarcoptiformesAstigmataPsoroptidiaAnalgoideaPyroglyphidaeDermatophagoidinaeDermatophagoides

Subcellular locationi

GO - Cellular componenti

  1. extracellular region Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Secreted

Pathology & Biotechi

Allergenic propertiesi

Causes an allergic reaction in human. Common symptoms of mite allergy are bronchial asthma, allergic rhinitis and conjunctivitis.

Keywords - Diseasei

Allergen

Protein family/group databases

Allergomei307. Der f 7.
3256. Der f 7.0101.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 1717 Reviewed prediction
Add
BLAST
Chaini18 – 213196Mite allergen Der f 7
PRO_0000001184Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Glycosylationi151 – 1511N-linked (GlcNAc...) Reviewed prediction

Keywords - PTMi

Glycoprotein

Proteomic databases

PRIDEiQ26456.

Structurei

Secondary structure

Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Helixi24 – 4118
Beta strandi43 – 519
Beta strandi54 – 618
Beta strandi63 – 7917
Helixi81 – 833
Beta strandi84 – 896
Beta strandi91 – 955
Beta strandi98 – 11013
Beta strandi112 – 12211
Beta strandi128 – 1369
Beta strandi139 – 15012
Beta strandi153 – 1597
Beta strandi163 – 1697
Helixi177 – 21135

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
3UV1X-ray2.00A/B18-213[»]
ProteinModelPortaliQ26456.

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Signal

Family and domain databases

InterProiIPR020234. Mite_allergen_group-7.
[Graphical view]
ProDomiPD037435. Mite_group-7_allergen. 1 hit.
[Graphical view] [Entries sharing at least one domain]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q26456-1 [UniParc]FASTAAdd to Basket

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MMKFLLIAAV AFVAVSADPI HYDKITEEIN KAIDDAIAAI EQSETIDPMK    50
VPDHADKFER HVGIVDFKGE LAMRNIEARG LKQMKRQGDA NVKGEEGIVK 100
AHLLIGVHDD IVSMEYDLAY KLGDLHPTTH VISDIQDFVV ALSLEISDEG 150
NITMTSFEVR QFANVVNHIG GLSILDPIFG VLSDVLTAIF QDTVRKEMTK 200
VLAPAFKREL EKN 213
Length:213
Mass (Da):23,627
Last modified:November 1, 1997 - v1
Checksum:i3CF1F529107B7808
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
S80655 mRNA. Translation: AAB35977.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
S80655 mRNA. Translation: AAB35977.1 .

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
Entry Method Resolution (Å) Chain Positions PDBsum
3UV1 X-ray 2.00 A/B 18-213 [» ]
ProteinModelPortali Q26456.
ModBasei Search...

Protein family/group databases

Allergomei 307. Der f 7.
3256. Der f 7.0101.

Proteomic databases

PRIDEi Q26456.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Family and domain databases

InterProi IPR020234. Mite_allergen_group-7.
[Graphical view ]
ProDomi PD037435. Mite_group-7_allergen. 1 hit.
[Graphical view ] [Entries sharing at least one domain ]
ProtoNeti Search...

Publicationsi

  1. "Molecular cloning and immunological characterization of the house dust mite allergen Der f 7."
    Shen H.-D., Chua K.-Y., Lin W.L., Hsieh K.-H., Thomas W.R.
    Clin. Exp. Allergy 25:1000-1006(1995) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA].

Entry informationi

Entry nameiALL7_DERFA
AccessioniPrimary (citable) accession number: Q26456
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: November 1, 1997
Last modified: April 3, 2013
This is version 45 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)

Miscellaneousi

Keywords - Technical termi

3D-structure

Documents

  1. Allergens
    Nomenclature of allergens and list of entries
  2. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  3. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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