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Q26456

- ALL7_DERFA

UniProt

Q26456 - ALL7_DERFA

Protein

Mite allergen Der f 7

Gene

DERF7

Organism
Dermatophagoides farinae (American house dust mite)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 46 (01 Oct 2014)
      Sequence version 1 (01 Nov 1997)
      Previous versions | rss
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    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Mite allergen Der f 7
    Alternative name(s):
    Allergen Der f VII
    Allergen: Der f 7
    Gene namesi
    Name:DERF7
    OrganismiDermatophagoides farinae (American house dust mite)
    Taxonomic identifieri6954 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaChelicerataArachnidaAcariAcariformesSarcoptiformesAstigmataPsoroptidiaAnalgoideaPyroglyphidaeDermatophagoidinaeDermatophagoides

    Subcellular locationi

    GO - Cellular componenti

    1. extracellular region Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Secreted

    Pathology & Biotechi

    Allergenic propertiesi

    Causes an allergic reaction in human. Common symptoms of mite allergy are bronchial asthma, allergic rhinitis and conjunctivitis.

    Keywords - Diseasei

    Allergen

    Protein family/group databases

    Allergomei307. Der f 7.
    3256. Der f 7.0101.

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Signal peptidei1 – 1717Sequence AnalysisAdd
    BLAST
    Chaini18 – 213196Mite allergen Der f 7PRO_0000001184Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Glycosylationi151 – 1511N-linked (GlcNAc...)Sequence Analysis

    Keywords - PTMi

    Glycoprotein

    Proteomic databases

    PRIDEiQ26456.

    Structurei

    Secondary structure

    1
    213
    Legend: HelixTurnBeta strand
    Show more details
    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Helixi24 – 4118
    Beta strandi43 – 519
    Beta strandi54 – 618
    Beta strandi63 – 7917
    Helixi81 – 833
    Beta strandi84 – 896
    Beta strandi91 – 955
    Beta strandi98 – 11013
    Beta strandi112 – 12211
    Beta strandi128 – 1369
    Beta strandi139 – 15012
    Beta strandi153 – 1597
    Beta strandi163 – 1697
    Helixi177 – 21135

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    EntryMethodResolution (Å)ChainPositionsPDBsum
    3UV1X-ray2.00A/B18-213[»]
    ProteinModelPortaliQ26456.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the mite group 7 allergen family.Curated

    Keywords - Domaini

    Signal

    Family and domain databases

    InterProiIPR020234. Mite_allergen_group-7.
    [Graphical view]
    ProDomiPD037435. Mite_group-7_allergen. 1 hit.
    [Graphical view] [Entries sharing at least one domain]

    Sequencei

    Sequence statusi: Complete.

    Sequence processingi: The displayed sequence is further processed into a mature form.

    Q26456-1 [UniParc]FASTAAdd to Basket

    « Hide

    MMKFLLIAAV AFVAVSADPI HYDKITEEIN KAIDDAIAAI EQSETIDPMK    50
    VPDHADKFER HVGIVDFKGE LAMRNIEARG LKQMKRQGDA NVKGEEGIVK 100
    AHLLIGVHDD IVSMEYDLAY KLGDLHPTTH VISDIQDFVV ALSLEISDEG 150
    NITMTSFEVR QFANVVNHIG GLSILDPIFG VLSDVLTAIF QDTVRKEMTK 200
    VLAPAFKREL EKN 213
    Length:213
    Mass (Da):23,627
    Last modified:November 1, 1997 - v1
    Checksum:i3CF1F529107B7808
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    S80655 mRNA. Translation: AAB35977.1.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    S80655 mRNA. Translation: AAB35977.1 .

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    Entry Method Resolution (Å) Chain Positions PDBsum
    3UV1 X-ray 2.00 A/B 18-213 [» ]
    ProteinModelPortali Q26456.
    ModBasei Search...
    MobiDBi Search...

    Protein family/group databases

    Allergomei 307. Der f 7.
    3256. Der f 7.0101.

    Proteomic databases

    PRIDEi Q26456.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Family and domain databases

    InterProi IPR020234. Mite_allergen_group-7.
    [Graphical view ]
    ProDomi PD037435. Mite_group-7_allergen. 1 hit.
    [Graphical view ] [Entries sharing at least one domain ]
    ProtoNeti Search...

    Publicationsi

    1. "Molecular cloning and immunological characterization of the house dust mite allergen Der f 7."
      Shen H.-D., Chua K.-Y., Lin W.L., Hsieh K.-H., Thomas W.R.
      Clin. Exp. Allergy 25:1000-1006(1995) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [MRNA].

    Entry informationi

    Entry nameiALL7_DERFA
    AccessioniPrimary (citable) accession number: Q26456
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: November 1, 1997
    Last sequence update: November 1, 1997
    Last modified: October 1, 2014
    This is version 46 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)

    Miscellaneousi

    Keywords - Technical termi

    3D-structure

    Documents

    1. Allergens
      Nomenclature of allergens and list of entries
    2. PDB cross-references
      Index of Protein Data Bank (PDB) cross-references
    3. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3