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Q26456 (ALL7_DERFA) Reviewed, UniProtKB/Swiss-Prot

Last modified April 3, 2013. Version 45. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Mite allergen Der f 7
Alternative name(s):
Allergen Der f VII
Allergen=Der f 7
Gene names
Name:DERF7
OrganismDermatophagoides farinae (American house dust mite)
Taxonomic identifier6954 [NCBI]
Taxonomic lineageEukaryotaMetazoaEcdysozoaArthropodaChelicerataArachnidaAcariAcariformesSarcoptiformesAstigmataPsoroptidiaAnalgoideaPyroglyphidaeDermatophagoidinaeDermatophagoides

Protein attributes

Sequence length213 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at protein level

General annotation (Comments)

Subcellular location

Secreted.

Allergenic properties

Causes an allergic reaction in human. Common symptoms of mite allergy are bronchial asthma, allergic rhinitis and conjunctivitis.

Sequence similarities

Belongs to the mite group 7 allergen family.

Ontologies

Keywords
   Cellular componentSecreted
   DiseaseAllergen
   DomainSignal
   PTMGlycoprotein
   Technical term3D-structure
Gene Ontology (GO)
   Cellular_componentextracellular region

Inferred from electronic annotation. Source: UniProtKB-SubCell

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 1717 Potential
Chain18 – 213196Mite allergen Der f 7
PRO_0000001184

Amino acid modifications

Glycosylation1511N-linked (GlcNAc...) Potential

Secondary structure

............................ 213
Helix Strand Turn

Details...

Sequences

Sequence LengthMass (Da)Tools
Q26456 [UniParc].

Last modified November 1, 1997. Version 1.
Checksum: 3CF1F529107B7808

FASTA21323,627
        10         20         30         40         50         60 
MMKFLLIAAV AFVAVSADPI HYDKITEEIN KAIDDAIAAI EQSETIDPMK VPDHADKFER 

        70         80         90        100        110        120 
HVGIVDFKGE LAMRNIEARG LKQMKRQGDA NVKGEEGIVK AHLLIGVHDD IVSMEYDLAY 

       130        140        150        160        170        180 
KLGDLHPTTH VISDIQDFVV ALSLEISDEG NITMTSFEVR QFANVVNHIG GLSILDPIFG 

       190        200        210 
VLSDVLTAIF QDTVRKEMTK VLAPAFKREL EKN 

« Hide

References

[1]"Molecular cloning and immunological characterization of the house dust mite allergen Der f 7."
Shen H.-D., Chua K.-Y., Lin W.L., Hsieh K.-H., Thomas W.R.
Clin. Exp. Allergy 25:1000-1006(1995) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [MRNA].
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
S80655 mRNA. Translation: AAB35977.1.

3D structure databases

PDBe
RCSB PDB
PDBj
EntryMethodResolution (Å)ChainPositionsPDBsum
3UV1X-ray2.00A/B18-213[»]
ProteinModelPortalQ26456.
ModBaseSearch...
MobiDBSearch...

Protein family/group databases

Allergome307. Der f 7.
3256. Der f 7.0101.

Proteomic databases

PRIDEQ26456.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Family and domain databases

InterProIPR020234. Mite_allergen_group-7.
[Graphical view]
ProDomPD037435. Mite_group-7_allergen. 1 hit.
[Graphical view] [Entries sharing at least one domain]
ProtoNetSearch...

Entry information

Entry nameALL7_DERFA
AccessionPrimary (citable) accession number: Q26456
Entry history
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: November 1, 1997
Last modified: April 3, 2013
This is version 45 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)

Relevant documents

SIMILARITY comments

Index of protein domains and families

PDB cross-references

Index of Protein Data Bank (PDB) cross-references

Allergens

Nomenclature of allergens and list of entries