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Protein
Submitted name:

Putative papain-like cysteine prorease

Gene

Pfa_SERA5

Organism
Plasmodium falciparum
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein inferred from homologyi

Functioni

GO - Molecular functioni

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Putative papain-like cysteine proreaseImported
Submitted name:
Serine rich protein (SERP I) geneImported
Gene namesi
Name:Pfa_SERA5Imported
OrganismiPlasmodium falciparumImported
Taxonomic identifieri5833 [NCBI]
Taxonomic lineageiEukaryotaAlveolataApicomplexaAconoidasidaHaemosporidaPlasmodiidaePlasmodiumPlasmodium (Laverania)

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 2424Sequence analysisAdd
BLAST
Chaini25 – 984960Sequence analysisPRO_5007700086Add
BLAST

Interactioni

Protein-protein interaction databases

MINTiMINT-8385925.
STRINGi5833.PFB0340c.

Structurei

3D structure databases

SMRiQ26016. Positions 551-815.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini556 – 807252Pept_C1InterPro annotationAdd
BLAST

Sequence similaritiesi

Belongs to the peptidase C1 family.SAAS annotation

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiKOG1543. Eukaryota.
COG4870. LUCA.

Family and domain databases

InterProiIPR025661. Pept_asp_AS.
IPR025660. Pept_his_AS.
IPR013128. Peptidase_C1A.
IPR000668. Peptidase_C1A_C.
[Graphical view]
PANTHERiPTHR12411. PTHR12411. 2 hits.
PfamiPF00112. Peptidase_C1. 1 hit.
[Graphical view]
SMARTiSM00645. Pept_C1. 1 hit.
[Graphical view]
PROSITEiPS00640. THIOL_PROTEASE_ASN. 1 hit.
PS00639. THIOL_PROTEASE_HIS. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q26016-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKSYISLFFI LCVIFNKNVI KCTGESQTGN TGGGQAGNTG GGQAGNTVGD
60 70 80 90 100
QAGSTGGSPQ GSTGASQPGS SEPSNPVSSG HSVSTVSVSQ TSTSSEKQDT
110 120 130 140 150
IQVKSALLKD YMGLKVTGPC NENFIMFLVP HIYIDVDTED TNIELRTTLK
160 170 180 190 200
ETNNAISFES NSGSLEKKKY VKLPSNGTTG EQSSSSSSSS SSNSSSSSSS
210 220 230 240 250
SSSSSSSSSS SSSSSSSSSS ESLPANGPDS PTVKPPRNLQ NICETGKNFK
260 270 280 290 300
LVVYIKENTL IIKWKVYGET KDTTENNKVD VRKYLINEKE TPFTSILIHA
310 320 330 340 350
YKEHNGTNLI ESKNYALGSD IPEKCDTLAS NCFLSGNFNI EKCFQCALLV
360 370 380 390 400
EKENKNDVCY KYLSEDIVSK FKEIKAETED DDEDDYTEYK LTESIDNILV
410 420 430 440 450
KMFKTNENND KSELIKLEEV DDSLKLELMN YCSLLKDVDT TGTLDNYGMG
460 470 480 490 500
NEMDIFNNLK RLLIYHSEEN INTLKNKFRN AAVCLKNVDD WIVNKRGLVL
510 520 530 540 550
PELNYDLEYF NEHLYNDKNS PEDKDNKGKG VVHVDTTLEK EDTLSYDNSD
560 570 580 590 600
NMFCNKEYCN RLKDENNCIS NLQVEDQGNC DTSWIFASKY HLETIRCMKG
610 620 630 640 650
YEPTKISALY VANCYKGEHK DRCDEGSSPM EFLQIIEDYG FLPAESNYPY
660 670 680 690 700
NYVKVGEQCP KVEDHWMNLW DNGKILHNKN EPNSLDGKGY TAYESERFHD
710 720 730 740 750
NMDAFVKIIK TEVMNKGSVI AYIKAENVMG YEFSGKKVQN LCGDDTADHA
760 770 780 790 800
VNIVGYGNYV NSEGEKKSYW IVRNSWGPYW GDEGYFKVDM YGPTHCHFNF
810 820 830 840 850
IHSVVIFNVD LPMNNKTTKK ESKIYDYYLK ASPEFYHNLY FKNFNVGKKN
860 870 880 890 900
LFSEKEDNEN NKKLGNNYII FGQDTAGSGQ SGKESNTALE SAGTSNEVSE
910 920 930 940 950
RVHVYHILKH IKDGKIRMGM RKYIDTQDVN KKHSCTRSYA FNPENYEKCV
960 970 980
NLCNVNWKTC EEKTSPGLCL SKLDTNNECY FCYV
Length:984
Mass (Da):110,480
Last modified:November 1, 1996 - v1
Checksum:iE407F06A4CBC5D4D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
J03983 Genomic DNA. Translation: AAA29765.1.
AB733766 Genomic DNA. Translation: BAR42378.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
J03983 Genomic DNA. Translation: AAA29765.1.
AB733766 Genomic DNA. Translation: BAR42378.1.

3D structure databases

SMRiQ26016. Positions 551-815.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

MINTiMINT-8385925.
STRINGi5833.PFB0340c.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Phylogenomic databases

eggNOGiKOG1543. Eukaryota.
COG4870. LUCA.

Family and domain databases

InterProiIPR025661. Pept_asp_AS.
IPR025660. Pept_his_AS.
IPR013128. Peptidase_C1A.
IPR000668. Peptidase_C1A_C.
[Graphical view]
PANTHERiPTHR12411. PTHR12411. 2 hits.
PfamiPF00112. Peptidase_C1. 1 hit.
[Graphical view]
SMARTiSM00645. Pept_C1. 1 hit.
[Graphical view]
PROSITEiPS00640. THIOL_PROTEASE_ASN. 1 hit.
PS00639. THIOL_PROTEASE_HIS. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ26016_PLAFA
AccessioniPrimary (citable) accession number: Q26016
Entry historyi
Integrated into UniProtKB/TrEMBL: November 1, 1996
Last sequence update: November 1, 1996
Last modified: September 7, 2016
This is version 63 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.