Q25B55 (Q25B55_DROME) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
CAST EMBL CAH61079.2

Gene names

Name:	brp FlyBase FBgn0083982 FlyBase FBgn0086376 FlyBase FBgn0259246
Synonyms:	Cast EMBL CAH61079.2

Organism

Drosophila melanogaster (Fruit fly) EMBL CAH61079.2

Taxonomic identifier

7227 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Arthropoda › Hexapoda › Insecta › Pterygota › Neoptera › Endopterygota › Diptera › Brachycera › Muscomorpha › Ephydroidea › Drosophilidae › Drosophila › Sophophora

Protein attributes

Sequence length	1740 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

Ontologies

Gene Ontology (GO)
Biological process	adult locomotory behavior Inferred from mutant phenotype Ref.1. Source: FlyBase anesthesia-resistant memory Inferred from direct assay. Source: FlyBase maintenance of presynaptic active zone structure Inferred from mutant phenotype Ref.1. Source: FlyBase neuromuscular synaptic transmission Inferred from mutant phenotype. Source: FlyBase regulation of synaptic plasticity Inferred from mutant phenotype. Source: FlyBase short-term memory Inferred from direct assay. Source: FlyBase
Cellular component	neuromuscular junction Inferred from direct assay. Source: FlyBase presynaptic active zone Inferred from direct assay Ref.1. Source: FlyBase
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q25B55 [UniParc]. Last modified April 18, 2006. Version 1. Checksum: DD83FF18F4D6D038	FASTA	1,740	201,652
	10 20 30 40 50 60 MGSPYYRDMD EPTSPAGAGH HRSRSASRPP MAHAMDYPRT RYQSLDRGGL VDPHDREFIP 70 80 90 100 110 120 IREPRDRSRD RSLERGLYLE DELYGRSARQ SPSAMGGYNT GMGPTSDRAY LGDLQHQNTD 130 140 150 160 170 180 LQRELGDLKR ELELTNQKLG SSMHSIKTFW SPELKKERAP RKEESAKYSL INDQLKLLST 190 200 210 220 230 240 ENQKQAMLVR QLEEELRLRM RQPNLEMRQQ MEAIYAENDH LQREISILRE TVKDLECRVE 250 260 270 280 290 300 TQKQTLIARD ESIKKLLEML QAKGMGKEEE RQMFQQMQAM AQKQLDEFRL EIQRRDQEIL 310 320 330 340 350 360 AMAAKMKTLE EQHQDYQRHI AVLKESLCAK EEHYNMLQTD VEEMRARLEE KNRLIEKKTQ 370 380 390 400 410 420 GTLQTVQERN RLTSELTELK DHMDIKDRKI SVLQRKIENL EDLLKEKDNQ VDMARARLSA 430 440 450 460 470 480 MQAHHSSSEG ALTSLEEAIG DKEKQMAQLR DQRDRAEHEK QEERDLHERE VADYKIKLRA 490 500 510 520 530 540 AESEVEKLQT RPERAVTERE RLEIKLEASQ SELGKSKAEL EKATCEMGRS SADWESTKQR 550 560 570 580 590 600 TARLELENER LKHDLERSQN VQKLMFETGK ISTTFGRTTM TTSQELDRAQ ERADKASAEL 610 620 630 640 650 660 RRTQAELRVT QSDAERAREE AAALQEKLEK SQGEVYRLKA KLENAQGEQE SLRQELEKAQ 670 680 690 700 710 720 SGVSRIHADR DRAFSEVEKI KEEMERTQAT LGKSQLQHEK LQNSLDKAQN EVDHLQDKLD 730 740 750 760 770 780 KACTENRRLV LEKEKLTYDY DNLQSQLDKA LGQAARMQKE RETLSLDTDR IREKLEKTQV 790 800 810 820 830 840 QLGRIQKERD QFSDELETLK ERSESAQTLL MKAARDREAM QTDLEVLKER YEKSHAIQQK 850 860 870 880 890 900 LQMERDDAVT EVEILKEKLD KALYASQKLI DEKDTSNKEF EKMLEKYDRA QNEIYRLQSR 910 920 930 940 950 960 CDTAEADRAR LEVEAERSGL AASKAREDLR KLQDESTRLQ EACDRAALQL SRAKECEDNA 970 980 990 1000 1010 1020 RSELEHSRDR FDKLQTDIRR AQGEKEHFQS ELERVTYELE RAHAAQTKAS ASVEAAKEEA 1030 1040 1050 1060 1070 1080 AHYAVELEKM RDRYEKSQVE LRKLQDTDTF GRETRRLKEE NERLREKLDK TLMELETIRG 1090 1100 1110 1120 1130 1140 KSQYESESFE KYKDKYEKIE MEVQNMESKL HETSLQLELS KGEVAKMLAN QEKQRSELER 1150 1160 1170 1180 1190 1200 AHIEREKARD KHEKLLKEVD RLRLQQSSVS PGDPVRASTS SSSALSAGER QEIDRLRDRL 1210 1220 1230 1240 1250 1260 EKALQSRDAT ELEAGRLAKE LEKAQMHLAK QQENTESTRI EFERMGAELG RLHDRLEKAE 1270 1280 1290 1300 1310 1320 AEREALRQAN RSGGAGAAPH PQLEKHVQKL ESDVKQLAME REQLVLQLEK SQEILMNFQK 1330 1340 1350 1360 1370 1380 ELQNAEAELQ KTREENRKLR NGHQVPPVAA PPAGPSPAEF QAMQKEIQTL QQKLQESERA 1390 1400 1410 1420 1430 1440 LQAAGPQQAQ AAAAAGASRE EIEQWRKVIE QEKSRADMAD KAAQEMHKRI QLMDQHIKDQ 1450 1460 1470 1480 1490 1500 HAQMQKMQQQ MQQQQQAAQQ AVQQAAQQQQ SAAGAGGADP KELEKVRGEL QAACTERDRF 1510 1520 1530 1540 1550 1560 QQQLELLVTE LEKSKMSNQE QAKQLQTAQQ QVQQLQQQVQ QLQQQMQQLQ QAASAGAGAT 1570 1580 1590 1600 1610 1620 DVQRQQLEQQ QKQLEEVRKQ IDNQAKATEG ERKIIDEQRK QIDAKRKDIE EKEKKMAEFD 1630 1640 1650 1660 1670 1680 VQLRKRKEQM DQLEKSLQTQ GGGAAAAGEL NKKLMDTQRQ LEACVKELQN TKEEHKKAAT 1690 1700 1710 1720 1730 1740 ETERLLQLVQ MSQEEQNAKE KTIMDLQQAL KIAQAKVKQA QTQQQQQQDA GPAGFLKSFF

References

[1]

"Bruchpilot, a protein with homology to ELKS/CAST, is required for structural integrity and function of synaptic active zones in Drosophila." Wagh D.A., Rasse T.M., Asan E., Hofbauer A., Schwenkert I., Durrbeck H., Buchner S., Dabauvalle M.C., Schmidt M., Qin G., Wichmann C., Kittel R., Sigrist S.J., Buchner E. Neuron 49:833-844(2006) [PubMed: 16543132] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Tissue: Nervous tissue EMBL CAH61079.2.

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Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AJ849544 mRNA. Translation: CAH61079.2.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	Q25B55.
Proteomic databases
PRIDE	Q25B55.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Organism-specific databases
FlyBase	FBgn0259246. brp.
Phylogenomic databases
eggNOG	inNOG08355.
InParanoid	Q25B55.
Gene expression databases
ArrayExpress	Q25B55.
Bgee	Q25B55.
Family and domain databases
InterPro	IPR019323. CAZ_cplx_RIM-bd_prot. [Graphical view]
Pfam	PF10174. Cast. 4 hits. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q25B55_DROME

Accession

Primary (citable) accession number: Q25B55

Entry history

Integrated into UniProtKB/TrEMBL:	April 18, 2006
Last sequence update:	April 18, 2006
Last modified:	November 16, 2011
This is version 32 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)