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Protein

Allergen Cr-PI

Gene
N/A
Organism
Periplaneta americana (American cockroach) (Blatta americana)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Larval storage protein (LSP) which may serve as a store of amino acids for synthesis of adult proteins.By similarity

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Storage protein

Names & Taxonomyi

Protein namesi
Recommended name:
Allergen Cr-PI
Alternative name(s):
Allergen: Per a 3
OrganismiPeriplaneta americana (American cockroach) (Blatta americana)
Taxonomic identifieri6978 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraOrthopteroideaDictyopteraBlattodeaBlattoideaBlattidaeBlattinaePeriplaneta

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Secreted

Pathology & Biotechi

Allergenic propertiesi

Causes an allergic reaction in human.

Keywords - Diseasei

Allergen

Protein family/group databases

Allergomei537. Per a 3.
538. Per a 3.0101.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 1616Sequence analysisAdd
BLAST
Chaini17 – 685669Allergen Cr-PIPRO_0000013339Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Glycosylationi233 – 2331N-linked (GlcNAc...)Sequence analysis

Keywords - PTMi

Glycoprotein

Structurei

3D structure databases

ProteinModelPortaliQ25641.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the hemocyanin family.Curated

Keywords - Domaini

Signal

Family and domain databases

Gene3Di1.10.1280.10. 1 hit.
1.20.1370.10. 1 hit.
2.60.40.1520. 1 hit.
InterProiIPR013788. Hemocyanin/hexamerin.
IPR000896. Hemocyanin/hexamerin_mid_dom.
IPR005203. Hemocyanin_C.
IPR005204. Hemocyanin_N.
IPR014756. Ig_E-set.
IPR008922. Unchr_di-copper_centre.
[Graphical view]
PANTHERiPTHR11511. PTHR11511. 1 hit.
PfamiPF03723. Hemocyanin_C. 1 hit.
PF00372. Hemocyanin_M. 1 hit.
PF03722. Hemocyanin_N. 1 hit.
[Graphical view]
PRINTSiPR00187. HAEMOCYANIN.
SUPFAMiSSF48050. SSF48050. 1 hit.
SSF48056. SSF48056. 1 hit.
SSF81296. SSF81296. 1 hit.
PROSITEiPS00210. HEMOCYANIN_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q25641-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKTALVFAAV VAFVAARFPD HKDYKQLADK QFLAKQRDVL RLFHRVHQHN
60 70 80 90 100
ILNDQVEVGI PMTSKQTSAT TVPPSGEAVH GVLQEGHARP RGEPFSVNYE
110 120 130 140 150
KHREQAIMLY DLLYFANDYD TFYKTACWAR DRVNEGMFMY SFSIAVFHRD
160 170 180 190 200
DMQGVMLPPP YEVYPYLFVD HDVIHMAQKY WMKNAGSGEH HSHVIPVNFT
210 220 230 240 250
LRTQDHLLAY FTSDVNLNAF NTYYRYYYPS WYNTTLYGHN IDRRGEQFYY
260 270 280 290 300
TYKQIYARYF LERLSNDLPD VYPFYYSKPV KSAYNPNLRY HNGEEMPVRP
310 320 330 340 350
SNMYVTNFDL YYIADIKNYE KRVEDAIDFG YAFDEHMKPH SLYHDVHGME
360 370 380 390 400
YLADMIEGNM DSPNFYFYGS IYHMYHSMIG HIVDPYHKMG LAPSLEHPET
410 420 430 440 450
VLRDPVFYQL WKRVDHLFQK YKNRLPRYTH DELAFEGVKV ENVDVGKLYT
460 470 480 490 500
YFEQYDMSLD MAVYVNNVDQ ISNVDVQLAV RLNHKPFTYN IEVSSDKAQD
510 520 530 540 550
VYVAVFLGPK YDYLGREYDL NDRRHYFVEM DRFPYHVGAG KTVIERNSHD
560 570 580 590 600
SNIIAPERDS YRTFYKKVQE AYEGKSQYYV DKGHNYCGYP ENLLIPKGKK
610 620 630 640 650
GGQAYTFYVI VTPYVKQDEH DFEPYNYKAF SYCGVGSERK YPDNKPLGYP
660 670 680
FDRKIYSNDF YTPNMYFKDV IIFHKKYDEV GVQGH
Length:685
Mass (Da):81,175
Last modified:November 1, 1997 - v1
Checksum:iB596E0BC96149877
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L40818 mRNA. Translation: AAB09629.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L40818 mRNA. Translation: AAB09629.1.

3D structure databases

ProteinModelPortaliQ25641.
ModBaseiSearch...
MobiDBiSearch...

Protein family/group databases

Allergomei537. Per a 3.
538. Per a 3.0101.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Family and domain databases

Gene3Di1.10.1280.10. 1 hit.
1.20.1370.10. 1 hit.
2.60.40.1520. 1 hit.
InterProiIPR013788. Hemocyanin/hexamerin.
IPR000896. Hemocyanin/hexamerin_mid_dom.
IPR005203. Hemocyanin_C.
IPR005204. Hemocyanin_N.
IPR014756. Ig_E-set.
IPR008922. Unchr_di-copper_centre.
[Graphical view]
PANTHERiPTHR11511. PTHR11511. 1 hit.
PfamiPF03723. Hemocyanin_C. 1 hit.
PF00372. Hemocyanin_M. 1 hit.
PF03722. Hemocyanin_N. 1 hit.
[Graphical view]
PRINTSiPR00187. HAEMOCYANIN.
SUPFAMiSSF48050. SSF48050. 1 hit.
SSF48056. SSF48056. 1 hit.
SSF81296. SSF81296. 1 hit.
PROSITEiPS00210. HEMOCYANIN_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiCRPI_PERAM
AccessioniPrimary (citable) accession number: Q25641
Secondary accession number(s): Q94644
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: November 1, 1997
Last modified: January 7, 2015
This is version 71 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)

Miscellaneousi

Documents

  1. Allergens
    Nomenclature of allergens and list of entries
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.