Q255P2 (GLMM_CHLFF) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Phosphoglucosamine mutase
EC=5.4.2.10

Gene names

Name:	glmM
Ordered Locus Names:	CF0224

Organism

Chlamydophila felis (strain Fe/C-56) [Complete proteome] [HAMAP]

Taxonomic identifier

264202 [NCBI]

Taxonomic lineage

Bacteria › Chlamydiae › Chlamydiales › Chlamydiaceae › Chlamydia/Chlamydophila group › Chlamydophila

Protein attributes

Sequence length	458 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate By similarity. HAMAP MF_01554_B
Catalytic activity	Alpha-D-glucosamine 1-phosphate = D-glucosamine 6-phosphate. HAMAP MF_01554_B
Cofactor	Binds 1 magnesium ion per subunit By similarity. HAMAP MF_01554_B
Post-translational modification	Activated by phosphorylation By similarity. HAMAP MF_01554_B
Sequence similarities	Belongs to the phosphohexose mutase family.

Ontologies

Keywords
Ligand	Magnesium Metal-binding
Molecular function	Isomerase
PTM	Phosphoprotein
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	carbohydrate metabolic process Inferred from electronic annotation. Source: InterPro
Molecular function	magnesium ion binding Inferred from electronic annotation. Source: InterPro phosphoglucosamine mutase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 458	458	Phosphoglucosamine mutase HAMAP MF_01554_B		PRO_0000301299
Sites
	Active site	106	1	Phosphoserine intermediate By similarity
	Metal binding	106	1	Magnesium; via phosphate group By similarity
	Metal binding	247	1	Magnesium By similarity
	Metal binding	249	1	Magnesium By similarity
	Metal binding	251	1	Magnesium By similarity
Amino acid modifications
	Modified residue	106	1	Phosphoserine By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q255P2 [UniParc]. Last modified April 18, 2006. Version 1. Checksum: 9AD5BD035E2EA52B	FASTA	458	49,681
	10 20 30 40 50 60 MTREIKPLFG TDGVRGRANH EPMTVEMSVL LGKAVAGVLQ ECKPGRHRVV VGKDTRLSGY 70 80 90 100 110 120 MFENALIAGL TSMGIETLVL GPIPTPGVAF ITRAYRADAG IMISASHNPY WDNGIKIFSS 130 140 150 160 170 180 EGFKISDVIE RRIEQMVAFK EFGNLPEDYA VGKNKRVVDA MGRYIEFAKA TFPRGRTLNG 190 200 210 220 230 240 LKIVLDCAHG AAYKVAPSVF EELDAEVICY GCEPTGSNIN DNCGALFPSV IQKAVIEHKA 250 260 270 280 290 300 DVGIALDGDG DRIIMVNEKG HIVDGDMILS ICANDLKKKG ILHGNRIVAT VMTNFGVLKY 310 320 330 340 350 360 LENVGIDTLI SPVGDRHVLQ NMLEYEANLG GEQSGHMIFL DYNTTGDGIV SALQVLRIMI 370 380 390 400 410 420 ESESTLSDLT SPIVKSPQAL INVAVKEKIP LDTLPLVQEA LRDVRSSLGD SGRVLLRYSG 430 440 450 TENICRVMVE GLKKHQVDSL AKTIADIVDS ELGVGIIE

References

[1]

"Genome sequence of the cat pathogen, Chlamydophila felis." Azuma Y., Hirakawa H., Yamashita A., Cai Y., Rahman M.A., Suzuki H., Mitaku S., Toh H., Goto S., Murakami T., Sugi K., Hayashi H., Fukushi H., Hattori M., Kuhara S., Shirai M. DNA Res. 13:15-23(2006) [PubMed: 16766509] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Fe/C-56.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AP006861 Genomic DNA. Translation: BAE80996.1.
RefSeq	YP_515141.1. NC_007899.1.
3D structure databases
HSSP	HSSP built from PDB template 2DKD based on UniProtKB Q9P4V2.
ProteinModelPortal	Q255P2.
ModBase	Search...
Protein-protein interaction databases
STRING	Q255P2.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	3958956.
GenomeReviews	Gene locus CF0224 in contig AP006861_GR.
KEGG	cfe:CF0224.
PATRIC	20204019. VBIChlFel51660_0232.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG1109.
HOGENOM	HBG644964.
OMA	IGSAKRI.
PhylomeDB	Q255P2.
ProtClustDB	PRK14314.
Enzyme and pathway databases
BioCyc	CFEL264202:CF0224-MONOMER.
Family and domain databases
HAMAP	MF_01554_B. GlmM_B. [Tree]
InterPro	IPR005844. A-D-PHexomutase_a/b/a-I. IPR016055. A-D-PHexomutase_a/b/a-I/II/III. IPR005845. A-D-PHexomutase_a/b/a-II. IPR005846. A-D-PHexomutase_a/b/a-III. IPR005843. A-D-PHexomutase_C. IPR016066. A-D-PHexomutase_CS. IPR005841. Alpha-D-phosphohexomutase_SF. IPR006352. GlmM. [Graphical view]
Gene3D	G3DSA:3.40.120.10. A-D-PHexomutase_a/b/a-I/II/III. 3 hits.
KO	K03431.
Pfam	PF02878. PGM_PMM_I. 1 hit. PF02879. PGM_PMM_II. 1 hit. PF02880. PGM_PMM_III. 1 hit. PF00408. PGM_PMM_IV. 1 hit. [Graphical view]
PRINTS	PR00509. PGMPMM.
SUPFAM	SSF53738. A-D-PHexomutase_a/b/a-I/II/III. 3 hits.
TIGRFAMs	TIGR01455. GlmM. 1 hit.
PROSITE	PS00710. PGM_PMM. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

GLMM_CHLFF

Accession

Primary (citable) accession number: Q255P2

Entry history

Integrated into UniProtKB/Swiss-Prot:	September 11, 2007
Last sequence update:	April 18, 2006
Last modified:	January 25, 2012
This is version 41 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program