ID   Q254Y0_CHLFF            Unreviewed;       618 AA.
AC   Q254Y0;
DT   18-APR-2006, integrated into UniProtKB/TrEMBL.
DT   18-APR-2006, sequence version 1.
DT   27-MAR-2024, entry version 88.
DE   RecName: Full=non-specific serine/threonine protein kinase {ECO:0000256|ARBA:ARBA00012513};
DE            EC=2.7.11.1 {ECO:0000256|ARBA:ARBA00012513};
GN   Name=pkn2 {ECO:0000313|EMBL:BAE81158.1};
GN   OrderedLocusNames=CF0386 {ECO:0000313|EMBL:BAE81158.1};
OS   Chlamydia felis (strain Fe/C-56) (Chlamydophila felis).
OC   Bacteria; Chlamydiota; Chlamydiia; Chlamydiales; Chlamydiaceae;
OC   Chlamydia/Chlamydophila group; Chlamydia.
OX   NCBI_TaxID=264202 {ECO:0000313|EMBL:BAE81158.1, ECO:0000313|Proteomes:UP000001260};
RN   [1] {ECO:0000313|EMBL:BAE81158.1, ECO:0000313|Proteomes:UP000001260}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Fe/C-56 {ECO:0000313|EMBL:BAE81158.1,
RC   ECO:0000313|Proteomes:UP000001260};
RX   PubMed=16766509; DOI=10.1093/dnares/dsi027;
RA   Azuma Y., Hirakawa H., Yamashita A., Cai Y., Rahman M.A., Suzuki H.,
RA   Mitaku S., Toh H., Goto S., Murakami T., Sugi K., Hayashi H., Fukushi H.,
RA   Hattori M., Kuhara S., Shirai M.;
RT   "Genome sequence of the cat pathogen, Chlamydophila felis.";
RL   DNA Res. 13:15-23(2006).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-
CC         [protein]; Xref=Rhea:RHEA:17989, Rhea:RHEA-COMP:9863, Rhea:RHEA-
CC         COMP:11604, ChEBI:CHEBI:15378, ChEBI:CHEBI:29999, ChEBI:CHEBI:30616,
CC         ChEBI:CHEBI:83421, ChEBI:CHEBI:456216; EC=2.7.11.1;
CC         Evidence={ECO:0000256|ARBA:ARBA00001433};
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L-
CC         threonyl-[protein]; Xref=Rhea:RHEA:46608, Rhea:RHEA-COMP:11060,
CC         Rhea:RHEA-COMP:11605, ChEBI:CHEBI:15378, ChEBI:CHEBI:30013,
CC         ChEBI:CHEBI:30616, ChEBI:CHEBI:61977, ChEBI:CHEBI:456216;
CC         EC=2.7.11.1; Evidence={ECO:0000256|ARBA:ARBA00000775};
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DR   EMBL; AP006861; BAE81158.1; -; Genomic_DNA.
DR   RefSeq; WP_011457938.1; NC_007899.1.
DR   AlphaFoldDB; Q254Y0; -.
DR   STRING; 264202.CF0386; -.
DR   KEGG; cfe:CF0386; -.
DR   eggNOG; COG0515; Bacteria.
DR   eggNOG; COG1262; Bacteria.
DR   HOGENOM; CLU_408763_0_0_0; -.
DR   OrthoDB; 9768004at2; -.
DR   Proteomes; UP000001260; Chromosome.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
DR   GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR   Gene3D; 3.90.1580.10; paralog of FGE (formylglycine-generating enzyme); 1.
DR   Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR   InterPro; IPR016187; CTDL_fold.
DR   InterPro; IPR011009; Kinase-like_dom_sf.
DR   InterPro; IPR000719; Prot_kinase_dom.
DR   InterPro; IPR001245; Ser-Thr/Tyr_kinase_cat_dom.
DR   InterPro; IPR005532; SUMF_dom.
DR   InterPro; IPR042095; SUMF_sf.
DR   PANTHER; PTHR23150:SF19; FORMYLGLYCINE-GENERATING ENZYME; 1.
DR   PANTHER; PTHR23150; SULFATASE MODIFYING FACTOR 1, 2; 1.
DR   Pfam; PF03781; FGE-sulfatase; 1.
DR   Pfam; PF07714; PK_Tyr_Ser-Thr; 1.
DR   SMART; SM00220; S_TKc; 1.
DR   SUPFAM; SSF56436; C-type lectin-like; 1.
DR   SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR   PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
PE   4: Predicted;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW   Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000313|EMBL:BAE81158.1};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Serine/threonine-protein kinase {ECO:0000313|EMBL:BAE81158.1};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT   DOMAIN          15..381
FT                   /note="Protein kinase"
FT                   /evidence="ECO:0000259|PROSITE:PS50011"
SQ   SEQUENCE   618 AA;  70110 MW;  CA296C20F1C53CA1 CRC64;
     MVNEQDIGVE FLGDYKILCY LRRGLWCQDI LAEHRFIKKR YILKIPHAEL TSSEAFMNAF
     HETIVKLATI KHPGIISIEN VSQVDGRYFL VTEEREVPTL SLTQYLASRP QGLSELEIQD
     LVCQLAEILD YAHARGLVHG GLSLDSVHVD LSGPSPKVFL PEIGFSFLLK DQYAQHLLAE
     LSEKSSFDKL KQMLLFQAPE PTSGTVVEDI YAFGVVVYVL LLRQFPQGVF PLPSEAFPNY
     IYDWDSLIKS CLSYSINQRP KKLSPLLVKK TAGELFVTAK AQCVEEELRE IGEEPQIPSV
     ANIIQESENQ IIEESSDHLA FVLVEAKSID EAMNTSVDST EEVIREDESY SNALQSLLIR
     EPVVSRYVEE EKEEIKPQPL FTEMVFIEGG GFFRGGREGQ RDEHPVHEIF LESFFLDIHP
     VTNEQFVRYL ECAGSEQDKY YNELIRLKDS RIQRRSGKLV IEPGYAKHPV VGVTWYGASG
     YASWVGKRLP TEAEWEVAAY GGIAQQRYPC GEEIDKSQAN FFSSDTTAVM SYPANPYGLY
     DMAGNVYEWC EDWYGYDFYE ISAQESHCPR GPAQGVYRVL RGGCWKSLKD DLRCAHRHRN
     NPGAVNSTYG FRCAKGVK
//