Q254M8 (SURE_CHLFF) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
5'-nucleotidase surE
EC=3.1.3.5

Alternative name(s):
Nucleoside 5'-monophosphate phosphohydrolase

Gene names

Name:	surE
Ordered Locus Names:	CF0488

Organism

Chlamydophila felis (strain Fe/C-56) [Complete proteome] [HAMAP]

Taxonomic identifier

264202 [NCBI]

Taxonomic lineage

Bacteria › Chlamydiae › Chlamydiales › Chlamydiaceae › Chlamydia/Chlamydophila group › Chlamydophila

Protein attributes

Sequence length	274 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates By similarity. HAMAP MF_00060
Catalytic activity	A 5'-ribonucleotide + H2O = a ribonucleoside + phosphate. HAMAP MF_00060
Cofactor	Binds 1 divalent metal cation per subunit By similarity.
Subcellular location	Cytoplasm Potential HAMAP MF_00060.
Sequence similarities	Belongs to the surE nucleotidase family.

Ontologies

Keywords
Cellular component	Cytoplasm
Ligand	Metal-binding Nucleotide-binding
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	5'-nucleotidase activity Inferred from electronic annotation. Source: EC metal ion binding Inferred from electronic annotation. Source: UniProtKB-KW nucleotide binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 274	274	5'-nucleotidase surE HAMAP MF_00060		PRO_1000007719
Sites
	Metal binding	12	1	Divalent metal cation By similarity
	Metal binding	13	1	Divalent metal cation By similarity
	Metal binding	45	1	Divalent metal cation By similarity
	Metal binding	103	1	Divalent metal cation By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q254M8 [UniParc]. Last modified April 18, 2006. Version 1. Checksum: 2DF86F4089687081	FASTA	274	30,277
	10 20 30 40 50 60 MNKKLKVLLT NDDGIFAKGI SLLVSNLLKA DFADLYIVAP NTEQSGKSMS FSYTEPVSIE 70 80 90 100 110 120 RVDYHQPVAG AWAVSGSPVD CIKLALGDLF LDSLPDIVLS GINNGSNAGR NIFYSGTAGA 130 140 150 160 170 180 AMEAVISGIP AIAFSQEEHI SCFQEKKSCE LIKMLVLYAL SRPFPLLTGF NVNFPACENN 190 200 210 220 230 240 EEWQGMKLVA TGKEFAYGVP RLLCDDGKRK FYSLNDCQRL MDEDLSEECH SLLTKKITVA 250 260 270 PLLVRNSPLG LMSEEEFQQL QQEFEDFIHS EIRS

References

[1]

"Genome sequence of the cat pathogen, Chlamydophila felis." Azuma Y., Hirakawa H., Yamashita A., Cai Y., Rahman M.A., Suzuki H., Mitaku S., Toh H., Goto S., Murakami T., Sugi K., Hayashi H., Fukushi H., Hattori M., Kuhara S., Shirai M. DNA Res. 13:15-23(2006) [PubMed: 16766509] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Fe/C-56.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AP006861 Genomic DNA. Translation: BAE81260.1.
RefSeq	YP_515405.1. NC_007899.1.
3D structure databases
ProteinModelPortal	Q254M8.
ModBase	Search...
Protein-protein interaction databases
STRING	Q254M8.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	3959090.
GenomeReviews	Gene locus CF0488 in contig AP006861_GR.
KEGG	cfe:CF0488.
PATRIC	20204602. VBIChlFel51660_0510.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0496.
HOGENOM	HBG600532.
OMA	SNAGRNI.
PhylomeDB	Q254M8.
ProtClustDB	PRK00346.
Enzyme and pathway databases
BioCyc	CFEL264202:CF0488-MONOMER.
Family and domain databases
HAMAP	MF_00060. SurE. [Tree]
InterPro	IPR002828. SurE-like_Pase/nucleotidase. [Graphical view]
Gene3D	G3DSA:3.40.1210.10. SurE-like_Pase/nucleotidase. 1 hit.
KO	K03787.
Pfam	PF01975. SurE. 1 hit. [Graphical view]
SUPFAM	SSF64167. SurE-like_Pase/nucleotidase. 1 hit.
TIGRFAMs	TIGR00087. SurE. 1 hit.
ProtoNet	Search...

Entry information

Entry name

SURE_CHLFF

Accession

Primary (citable) accession number: Q254M8

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
Last sequence update:	April 18, 2006
Last modified:	January 25, 2012
This is version 37 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program