Reviewed, UniProtKB/Swiss-Prot Q254B3 (DCD_CHLFF)

Names and origin

Protein names

Recommended name:
    Deoxycytidine triphosphate deaminase
      Short name=dCTP deaminase
    EC=3.5.4.13

Gene names

Name:	dcd
Ordered Locus Names:	CF0603

Organism

Chlamydophila felis (strain Fe/C-56) [Complete proteome] [HAMAP]

Taxonomic identifier

264202 [NCBI]

Taxonomic lineage

Bacteria › Chlamydiae › Chlamydiales › Chlamydiaceae › Chlamydophila

Protein attributes

Sequence length	190 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	dCTP + H2O = dUTP + NH3. HAMAP MF_00146
Pathway	Pyrimidine metabolism; dUMP biosynthesis; dUMP from dCTP (dUTP route): step 1/2. HAMAP MF_00146
Sequence similarities	Belongs to the dCTP deaminase family.

Ontologies

Keywords
Biological process	Nucleotide metabolism
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	dUTP biosynthetic process Inferred from electronic annotation. Source: InterPro pyrimidine ribonucleotide biosynthetic process Inferred from electronic annotation. Source: HAMAP
Molecular function	dCTP deaminase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 190	190	Deoxycytidine triphosphate deaminase HAMAP MF_00146		PRO_1000009704

Sequences

	Sequence		Length	Mass (Da)
	Q254B3-1 [UniParc]. Last modified April 18, 2006. Version 1. Checksum: 443D0B85432DE31C	FASTA	190	21,591
	10 20 30 40 50 60 MSIKEDKWIR KMAQTHGMIE PFADGQVNID AETGEKLISY GLSSYGYDLR LSREFKVFTN 70 80 90 100 110 120 VYNSLVDPKH FTEDTFISIT DDVCIIPPNS FALAHSVEYF RIPRNVLTMC IGKSTYARCG 130 140 150 160 170 180 LIVNVTPFEP EWEGYVTIEI SNTTPLPAKI YANEGIAQVL FFEADEMCEV SYAERKGKYQ 190 KQQGITVPFV

References

[1]

"Genome sequence of the cat pathogen, Chlamydophila felis." Azuma Y., Hirakawa H., Yamashita A., Cai Y., Rahman M.A., Suzuki H., Mitaku S., Toh H., Goto S., Murakami T., Sugi K., Hayashi H., Fukushi H., Hattori M., Kuhara S., Shirai M. DNA Res. 13:15-23(2006) [PubMed: 16766509] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	AP006861 Genomic DNA. Translation: BAE81375.1.
RefSeq	YP_515520.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	Q254B3.
Genome annotation databases
GeneID	3958687.
GenomeReviews	Gene locus CF0603 in contig AP006861_GR.
KEGG	cfe:CF0603.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q254B3.
OMA	CAQVLFF.
Family and domain databases
HAMAP	MF_00146. [Tree]
InterPro	IPR011962. dCTP_deam. [Graphical view]
ProDom	PD004900. dCTP_deaminase. 1 hit. [Graphical view] [Entries sharing at least one domain]
TIGRFAMs	TIGR02274. dCTP_deam. 1 hit.
ProtoNet	Search...

Entry information

Entry name

DCD_CHLFF

Accession

Primary (citable) accession number: Q254B3

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
Last sequence update:	April 18, 2006
Last modified:	November 3, 2009
This is version 22 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)