Q25442 (Q25442_MUSDO) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names	Submitted name: Transposase EMBL AAC37217.1
Organism	Musca domestica (House fly) EMBL AAC37217.1
Taxonomic identifier	7370 [NCBI]
Taxonomic lineage	Eukaryota › Metazoa › Arthropoda › Hexapoda › Insecta › Pterygota › Neoptera › Endopterygota › Diptera › Brachycera › Muscomorpha › Muscoidea › Muscidae › Musca

Protein attributes

Sequence length	612 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

Ontologies

Keywords
Technical term	3D-structure PDB 2BW3
Gene Ontology (GO)
Molecular function	DNA binding Inferred from electronic annotation. Source: InterPro protein dimerization activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q25442 [UniParc]. Last modified November 1, 1996. Version 1. Checksum: BA7B1475672E49DF	FASTA	612	70,110
	10 20 30 40 50 60 MQKMDNLEVK AKINQGLYKI TPRHKGTSFI WNVLADIQKE DDTLVEGWVF CRKCEKVLKY 70 80 90 100 110 120 TTRQTSNLCR HKCCASLKQS RELKTVSADC KKEAIEKCAQ WVVRDCRPFS AVSGSGFIDM 130 140 150 160 170 180 IKFFIKVGAE YGEHVNVEEL LPSPITLSRK VTSDAKEKKA LISREIKSAV EKDGASATID 190 200 210 220 230 240 LWTDNYIKRN FLGVTLHYHE NNELRDLILG LKSLDFERST AENIYKKLKA IFLQFNVEDL 250 260 270 280 290 300 SSIKFVTDRG ANVVKSLANN IRINCSSHLL SNVLENSFEE TPELNVPILA CKNIVKYFKK 310 320 330 340 350 360 ANLQHRLRSS LKSECPTRWN STYTMLRSIL DNWESVIQIL SEAGETQRIV HINKSIIQTM 370 380 390 400 410 420 VNILDGFERI FKELQTCSSP SLCFVVPSIL KVKEICSPDV GDVADIAKLK VNIIKNVRII 430 440 450 460 470 480 WEENLSIWHY TAFFFYPPAL HMQQEKVAQI KEFCLSKMED LELINRMSSF NELSATQLNQ 490 500 510 520 530 540 SDSNSHNSID LTSHSKDIST TSFFFPQLTQ NNSREPPVCP SDEFEFYRKE IVILSEDFKV 550 560 570 580 590 600 MEWWNLNSKK YPKLSKLALS LLSIPASSAA SERTFSLAGN IITEKRNRIG QQTVDSLLFL 610 NSFYKNFCKL DI

References

[1]	"The hobo transposable element of Drosophila can be cross-mobilized in houseflies and excises like the Ac element of maize." Atkinson P.W., Warren W.D., O'Brochta D.A. Proc. Natl. Acad. Sci. U.S.A. 90:9693-9697(1993) [PubMed: 8415764] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: Maryland EMBL AAC37217.1.
[2]	"The Hermes transposable element from the house fly, Musca domestica, is a short inverted repeat-type element of the hobo, Ac, and Tam3 (hAT) element family." Warren W.D., Atkinson P.W., O'Brochta D.A. Genet. Res. 64:87-97(1994) [PubMed: 7813905] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: Maryland EMBL AAC37217.1.
[3]	"Molecular architecture of a eukaryotic DNA transposase." Hickman A.B., Perez Z.N., Zhou L., Musingarimi P., Ghirlando R., Hinshaw J.E., Craig N.L., Dyda F. Nat. Struct. Mol. Biol. 12:715-721(2005) [PubMed: 16041385] [Abstract] Cited for: X-RAY CRYSTALLOGRAPHY (2.00 ANGSTROMS) OF 79-609 AND 79-158.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ

L34807 Genomic DNA. Translation: AAC37217.1.

3D structure databases

PDBe
RCSB PDB
PDBj

Entry	Method	Resolution (Å)	Chain	Positions	PDBsum
2BW3	X-ray	2.00	A	79-609	[»]
			B	79-158	[»]

ProteinModelPortal

Q25442.

SMR

Q25442. Positions 79-609.

ModBase

Search...

Protocols and materials databases

StructuralBiologyKnowledgebase

Search...

Family and domain databases

InterPro

IPR008906. HATC.
IPR018473. Hermes_transposase_DNA-db.
IPR012337. RNaseH-like_dom.
IPR003656. Znf_BED_prd.
[Graphical view]

Pfam

PF10683. DBD_Tnp_Hermes. 1 hit.
PF05699. Dimer_Tnp_hAT. 1 hit.
[Graphical view]

SMART

SM00614. ZnF_BED. 1 hit.
[Graphical view]

SUPFAM

SSF53098. RNaseH_fold. 1 hit.

PROSITE

PS50808. ZF_BED. 1 hit.
[Graphical view]

ProtoNet

Search...

Entry information

Entry name

Q25442_MUSDO

Accession

Primary (citable) accession number: Q25442

Entry history

Integrated into UniProtKB/TrEMBL:	November 1, 1996
Last sequence update:	November 1, 1996
Last modified:	December 14, 2011
This is version 47 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)