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Q25434

- FP1_MYTCO

UniProt

Q25434 - FP1_MYTCO

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Protein

Adhesive plaque matrix protein

Gene

FP1

Organism
Mytilus coruscus (Sea mussel)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at transcript leveli

Functioni

Provides adhesiveness to the mussel's foot. Mussels produce one of the strongest water insoluble glues. The mussel's adhesive is a bundle of threads, called a byssus, formed by a fibrous collagenous core coated with adhesive proteins.

Names & Taxonomyi

Protein namesi
Recommended name:
Adhesive plaque matrix protein
Alternative name(s):
Foot protein 1
MCFP1
Gene namesi
Name:FP1
OrganismiMytilus coruscus (Sea mussel)
Taxonomic identifieri42192 [NCBI]
Taxonomic lineageiEukaryotaMetazoaLophotrochozoaMolluscaBivalviaPteriomorphiaMytiloidaMytiloideaMytilidaeMytilinaeMytilus

Subcellular locationi

GO - Cellular componenti

  1. extracellular region Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 2020Sequence AnalysisAdd
BLAST
Chaini21 – 872852Adhesive plaque matrix proteinPRO_0000021285Add
BLAST

Post-translational modificationi

Hydroxylated on proline (mono- or dihydroxylation) and tyrosine residues (to L-DOPA = 3',4'-dihydroxyphenylalanine) of the tandem repeats.

Keywords - PTMi

Hydroxylation

Expressioni

Tissue specificityi

Produced by the byssal gland.

Structurei

3D structure databases

ProteinModelPortaliQ25434.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Repeati124 – 133101
Repeati134 – 143102
Repeati144 – 153103
Repeati154 – 163104
Repeati174 – 183105
Repeati184 – 19296
Repeati193 – 202107
Repeati203 – 212108
Repeati213 – 22199
Repeati222 – 2311010
Repeati232 – 2411011
Repeati242 – 2511012
Repeati252 – 2611013
Repeati262 – 2711014
Repeati272 – 2811015
Repeati282 – 2911016
Repeati292 – 3011017
Repeati302 – 3111018
Repeati312 – 3211019
Repeati322 – 3311020
Repeati332 – 3411021
Repeati342 – 3511022
Repeati352 – 3611023
Repeati362 – 3711024
Repeati372 – 3811025
Repeati382 – 3911026
Repeati402 – 4111027
Repeati412 – 4211028
Repeati422 – 4311029
Repeati432 – 4411030
Repeati442 – 4511031
Repeati452 – 4611032
Repeati462 – 4711033
Repeati472 – 4811034
Repeati482 – 4911035
Repeati502 – 5111036
Repeati512 – 5211037
Repeati522 – 5311038
Repeati532 – 5411039
Repeati542 – 5511040
Repeati552 – 5611041
Repeati562 – 5711042
Repeati572 – 5811043
Repeati582 – 5911044
Repeati602 – 6111045
Repeati612 – 6211046
Repeati622 – 6311047
Repeati632 – 6411048
Repeati642 – 6511049
Repeati652 – 6611050
Repeati662 – 6711051
Repeati672 – 6811052
Repeati682 – 6911053
Repeati702 – 7111054
Repeati712 – 7211055
Repeati722 – 7311056
Repeati732 – 7411057
Repeati742 – 7511058
Repeati752 – 7611059
Repeati762 – 7711060
Repeati772 – 7811061
Repeati782 – 7911062
Repeati792 – 8011063
Repeati812 – 8211064
Repeati822 – 8311065
Repeati832 – 8411066
Repeati842 – 8511067
Repeati852 – 8611068
Repeati862 – 8711069

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni21 – 4121Nonrepetitive linkerAdd
BLAST
Regioni124 – 87174869 X 10 AA tandem repeats of Y-[KRQ]-[PSTAHQR]-K-[AIPTSKGV]-[STR]-Y-[PTSVA]-[PSTQA]-[STYIPAQ]Add
BLAST
Regioni184 – 1929Nonapeptide 1
Regioni213 – 2219Nonapeptide 2

Domaini

Almost exclusively composed of repeats of a decapeptide.

Keywords - Domaini

Repeat, Signal

Family and domain databases

InterProiIPR002964. Adhesive_plaq.
[Graphical view]
PRINTSiPR01216. ADHESIVEI.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q25434-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MEGIKLNLCL LCIFSCDIFA LSNGNIHNVY GSAYSGASAG AYKTLPGSHP
60 70 80 90 100
YGSKHVPVYK PMNKIPTPYI SKKSYPAPYK PKGYYPTKRY QPTYGSKTNY
110 120 130 140 150
PPIYKPIAKK LSSYKAIKTT YPAYKAKTSY PPSYKHKITY PPTYKPKITY
160 170 180 190 200
PPTYKQKPSY PPSYKPKTTY PPTYKPKITY PPTYKRKPSY TPYKPKATYP
210 220 230 240 250
PTYKPKITYP PTYKRKPSYT PYKPKTTYPP TYKPKISYPS IYKPKASYVS
260 270 280 290 300
SYKSKKTYPP TYKPKISYPP TYKPKPSYPP TYKPKVTYPP TYKPKPSYPP
310 320 330 340 350
TYKPKITYPP TYKPKPSYPT PYKQKPSYPP IYKSKSSYPT SYKSKKTYPP
360 370 380 390 400
TYKPKITYPP TYKPKPSYPP SYKPKKTYSP TYKPKITYPP TYKPKPSYPP
410 420 430 440 450
SYKPKTTYPP TYKPKISYPP TYKPKASYVS SYKSKKTYPP TYKPKISYPP
460 470 480 490 500
TYKPKPSYPP TYKPKITYPP TYKPKPSYPP TYKPKITYPP TYKRKPSYPT
510 520 530 540 550
PYKQKPSYPP IYKSKSSYPT SYKSKKTYPP TYKPKITYPP TYKPKPSYPP
560 570 580 590 600
SYKPKTTYPP TYKPKIRYPP TYKPKASYPP TYKPKITYPP TYKPKPSYPT
610 620 630 640 650
PYKQKPSYPP IYKSKSSYPT AYKSKKTYPP TYKPKITYPP TYKPKPSYPP
660 670 680 690 700
SYRPKITYPP TYKPKKSYPQ AYKSKGSYPP SYQPKKTYPP SYKPKKTYPP
710 720 730 740 750
TYKPKISYPP TYKTKPSYPA SYKRKTSYPP TYKPKISYPS TYKAKPSYPP
760 770 780 790 800
TYKPKPSYAS SYKPKIRYPP TYKPKPSYAS SYKPKIRYPP TYKPKPSYAS
810 820 830 840 850
SYKPKIRYPP TYKPKPSYAS SYKPKITYPP TYKPKISYPP TYKPKITYPP
860 870
TYKPKISYPP AYKPKISYPS QY
Length:872
Mass (Da):101,678
Last modified:November 1, 1996 - v1
Checksum:i98CC70D7C75FF3C4
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
D63777 mRNA. Translation: BAA09850.1.

Cross-referencesi

Web resourcesi

Protein Spotlight

Sticky business - Issue 2 of September 2001

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
D63777 mRNA. Translation: BAA09850.1 .

3D structure databases

ProteinModelPortali Q25434.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Family and domain databases

InterProi IPR002964. Adhesive_plaq.
[Graphical view ]
PRINTSi PR01216. ADHESIVEI.
ProtoNeti Search...

Publicationsi

  1. "Adhesive protein cDNA sequence of the mussel Mytilus coruscus and its evolutionary implications."
    Inoue K., Takeuchi Y., Takeyama S., Yamaha E., Yamazaki F., Odo S., Harayama S.
    J. Mol. Evol. 43:348-356(1996) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA].
    Tissue: Foot.

Entry informationi

Entry nameiFP1_MYTCO
AccessioniPrimary (citable) accession number: Q25434
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 30, 2000
Last sequence update: November 1, 1996
Last modified: October 29, 2014
This is version 63 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)

Miscellaneousi

Documents

  1. Protein Spotlight
    Protein Spotlight articles and cited UniProtKB/Swiss-Prot entries

External Data

Dasty 3