Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Adhesive plaque matrix protein

Gene

FP1

Organism
Mytilus coruscus (Sea mussel)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

Provides adhesiveness to the mussel's foot. Mussels produce one of the strongest water insoluble glues. The mussel's adhesive is a bundle of threads, called a byssus, formed by a fibrous collagenous core coated with adhesive proteins.

Names & Taxonomyi

Protein namesi
Recommended name:
Adhesive plaque matrix protein
Alternative name(s):
Foot protein 1
MCFP1
Gene namesi
Name:FP1
OrganismiMytilus coruscus (Sea mussel)
Taxonomic identifieri42192 [NCBI]
Taxonomic lineageiEukaryotaMetazoaLophotrochozoaMolluscaBivalviaPteriomorphiaMytiloidaMytiloideaMytilidaeMytilinaeMytilus

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 20Sequence analysisAdd BLAST20
ChainiPRO_000002128521 – 872Adhesive plaque matrix proteinAdd BLAST852

Post-translational modificationi

Hydroxylated on proline (mono- or dihydroxylation) and tyrosine residues (to L-DOPA = 3',4'-dihydroxyphenylalanine) of the tandem repeats.

Keywords - PTMi

Hydroxylation

Expressioni

Tissue specificityi

Produced by the byssal gland.

Structurei

3D structure databases

ProteinModelPortaliQ25434.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Repeati124 – 133110
Repeati134 – 143210
Repeati144 – 153310
Repeati154 – 163410
Repeati174 – 183510
Repeati184 – 19269
Repeati193 – 202710
Repeati203 – 212810
Repeati213 – 22199
Repeati222 – 2311010
Repeati232 – 2411110
Repeati242 – 2511210
Repeati252 – 2611310
Repeati262 – 2711410
Repeati272 – 2811510
Repeati282 – 2911610
Repeati292 – 3011710
Repeati302 – 3111810
Repeati312 – 3211910
Repeati322 – 3312010
Repeati332 – 3412110
Repeati342 – 3512210
Repeati352 – 3612310
Repeati362 – 3712410
Repeati372 – 3812510
Repeati382 – 3912610
Repeati402 – 4112710
Repeati412 – 4212810
Repeati422 – 4312910
Repeati432 – 4413010
Repeati442 – 4513110
Repeati452 – 4613210
Repeati462 – 4713310
Repeati472 – 4813410
Repeati482 – 4913510
Repeati502 – 5113610
Repeati512 – 5213710
Repeati522 – 5313810
Repeati532 – 5413910
Repeati542 – 5514010
Repeati552 – 5614110
Repeati562 – 5714210
Repeati572 – 5814310
Repeati582 – 5914410
Repeati602 – 6114510
Repeati612 – 6214610
Repeati622 – 6314710
Repeati632 – 6414810
Repeati642 – 6514910
Repeati652 – 6615010
Repeati662 – 6715110
Repeati672 – 6815210
Repeati682 – 6915310
Repeati702 – 7115410
Repeati712 – 7215510
Repeati722 – 7315610
Repeati732 – 7415710
Repeati742 – 7515810
Repeati752 – 7615910
Repeati762 – 7716010
Repeati772 – 7816110
Repeati782 – 7916210
Repeati792 – 8016310
Repeati812 – 8216410
Repeati822 – 8316510
Repeati832 – 8416610
Repeati842 – 8516710
Repeati852 – 8616810
Repeati862 – 8716910

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni21 – 41Nonrepetitive linkerAdd BLAST21
Regioni124 – 87169 X 10 AA tandem repeats of Y-[KRQ]-[PSTAHQR]-K-[AIPTSKGV]-[STR]-Y-[PTSVA]-[PSTQA]-[STYIPAQ]Add BLAST748
Regioni184 – 192Nonapeptide 19
Regioni213 – 221Nonapeptide 29

Domaini

Almost exclusively composed of repeats of a decapeptide.

Keywords - Domaini

Repeat, Signal

Family and domain databases

InterProiIPR002964. Adhesive_plaq.
[Graphical view]
PRINTSiPR01216. ADHESIVEI.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q25434-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEGIKLNLCL LCIFSCDIFA LSNGNIHNVY GSAYSGASAG AYKTLPGSHP
60 70 80 90 100
YGSKHVPVYK PMNKIPTPYI SKKSYPAPYK PKGYYPTKRY QPTYGSKTNY
110 120 130 140 150
PPIYKPIAKK LSSYKAIKTT YPAYKAKTSY PPSYKHKITY PPTYKPKITY
160 170 180 190 200
PPTYKQKPSY PPSYKPKTTY PPTYKPKITY PPTYKRKPSY TPYKPKATYP
210 220 230 240 250
PTYKPKITYP PTYKRKPSYT PYKPKTTYPP TYKPKISYPS IYKPKASYVS
260 270 280 290 300
SYKSKKTYPP TYKPKISYPP TYKPKPSYPP TYKPKVTYPP TYKPKPSYPP
310 320 330 340 350
TYKPKITYPP TYKPKPSYPT PYKQKPSYPP IYKSKSSYPT SYKSKKTYPP
360 370 380 390 400
TYKPKITYPP TYKPKPSYPP SYKPKKTYSP TYKPKITYPP TYKPKPSYPP
410 420 430 440 450
SYKPKTTYPP TYKPKISYPP TYKPKASYVS SYKSKKTYPP TYKPKISYPP
460 470 480 490 500
TYKPKPSYPP TYKPKITYPP TYKPKPSYPP TYKPKITYPP TYKRKPSYPT
510 520 530 540 550
PYKQKPSYPP IYKSKSSYPT SYKSKKTYPP TYKPKITYPP TYKPKPSYPP
560 570 580 590 600
SYKPKTTYPP TYKPKIRYPP TYKPKASYPP TYKPKITYPP TYKPKPSYPT
610 620 630 640 650
PYKQKPSYPP IYKSKSSYPT AYKSKKTYPP TYKPKITYPP TYKPKPSYPP
660 670 680 690 700
SYRPKITYPP TYKPKKSYPQ AYKSKGSYPP SYQPKKTYPP SYKPKKTYPP
710 720 730 740 750
TYKPKISYPP TYKTKPSYPA SYKRKTSYPP TYKPKISYPS TYKAKPSYPP
760 770 780 790 800
TYKPKPSYAS SYKPKIRYPP TYKPKPSYAS SYKPKIRYPP TYKPKPSYAS
810 820 830 840 850
SYKPKIRYPP TYKPKPSYAS SYKPKITYPP TYKPKISYPP TYKPKITYPP
860 870
TYKPKISYPP AYKPKISYPS QY
Length:872
Mass (Da):101,678
Last modified:November 1, 1996 - v1
Checksum:i98CC70D7C75FF3C4
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
D63777 mRNA. Translation: BAA09850.1.

Cross-referencesi

Web resourcesi

Protein Spotlight

Sticky business - Issue 2 of September 2001

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
D63777 mRNA. Translation: BAA09850.1.

3D structure databases

ProteinModelPortaliQ25434.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Family and domain databases

InterProiIPR002964. Adhesive_plaq.
[Graphical view]
PRINTSiPR01216. ADHESIVEI.
ProtoNetiSearch...

Entry informationi

Entry nameiFP1_MYTCO
AccessioniPrimary (citable) accession number: Q25434
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 30, 2000
Last sequence update: November 1, 1996
Last modified: January 7, 2015
This is version 64 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)

Miscellaneousi

Documents

  1. Protein Spotlight
    Protein Spotlight articles and cited UniProtKB/Swiss-Prot entries

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.