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Q25434 (FP1_MYTCO) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 61. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Web links·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Adhesive plaque matrix protein
Alternative name(s):
Foot protein 1
MCFP1
Gene names
Name:FP1
OrganismMytilus coruscus (Sea mussel)
Taxonomic identifier42192 [NCBI]
Taxonomic lineageEukaryotaMetazoaLophotrochozoaMolluscaBivalviaPteriomorphiaMytiloidaMytiloideaMytilidaeMytilinaeMytilus

Protein attributes

Sequence length872 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at transcript level

General annotation (Comments)

Function

Provides adhesiveness to the mussel's foot. Mussels produce one of the strongest water insoluble glues. The mussel's adhesive is a bundle of threads, called a byssus, formed by a fibrous collagenous core coated with adhesive proteins.

Subcellular location

Secreted.

Tissue specificity

Produced by the byssal gland.

Domain

Almost exclusively composed of repeats of a decapeptide.

Post-translational modification

Hydroxylated on proline (mono- or dihydroxylation) and tyrosine residues (to L-DOPA = 3',4'-dihydroxyphenylalanine) of the tandem repeats.

Ontologies

Keywords
   Cellular componentSecreted
   DomainRepeat
Signal
   PTMHydroxylation
Gene Ontology (GO)
   Cellular_componentextracellular region

Inferred from electronic annotation. Source: UniProtKB-SubCell

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 2020 Potential
Chain21 – 872852Adhesive plaque matrix protein
PRO_0000021285

Regions

Repeat124 – 133101
Repeat134 – 143102
Repeat144 – 153103
Repeat154 – 163104
Repeat174 – 183105
Repeat184 – 19296
Repeat193 – 202107
Repeat203 – 212108
Repeat213 – 22199
Repeat222 – 2311010
Repeat232 – 2411011
Repeat242 – 2511012
Repeat252 – 2611013
Repeat262 – 2711014
Repeat272 – 2811015
Repeat282 – 2911016
Repeat292 – 3011017
Repeat302 – 3111018
Repeat312 – 3211019
Repeat322 – 3311020
Repeat332 – 3411021
Repeat342 – 3511022
Repeat352 – 3611023
Repeat362 – 3711024
Repeat372 – 3811025
Repeat382 – 3911026
Repeat402 – 4111027
Repeat412 – 4211028
Repeat422 – 4311029
Repeat432 – 4411030
Repeat442 – 4511031
Repeat452 – 4611032
Repeat462 – 4711033
Repeat472 – 4811034
Repeat482 – 4911035
Repeat502 – 5111036
Repeat512 – 5211037
Repeat522 – 5311038
Repeat532 – 5411039
Repeat542 – 5511040
Repeat552 – 5611041
Repeat562 – 5711042
Repeat572 – 5811043
Repeat582 – 5911044
Repeat602 – 6111045
Repeat612 – 6211046
Repeat622 – 6311047
Repeat632 – 6411048
Repeat642 – 6511049
Repeat652 – 6611050
Repeat662 – 6711051
Repeat672 – 6811052
Repeat682 – 6911053
Repeat702 – 7111054
Repeat712 – 7211055
Repeat722 – 7311056
Repeat732 – 7411057
Repeat742 – 7511058
Repeat752 – 7611059
Repeat762 – 7711060
Repeat772 – 7811061
Repeat782 – 7911062
Repeat792 – 8011063
Repeat812 – 8211064
Repeat822 – 8311065
Repeat832 – 8411066
Repeat842 – 8511067
Repeat852 – 8611068
Repeat862 – 8711069
Region21 – 4121Nonrepetitive linker
Region124 – 87174869 X 10 AA tandem repeats of Y-[KRQ]-[PSTAHQR]-K-[AIPTSKGV]-[STR]-Y-[PTSVA]-[PSTQA]-[STYIPAQ]
Region184 – 1929Nonapeptide 1
Region213 – 2219Nonapeptide 2

Sequences

Sequence LengthMass (Da)Tools
Q25434 [UniParc].

Last modified November 1, 1996. Version 1.
Checksum: 98CC70D7C75FF3C4

FASTA872101,678
        10         20         30         40         50         60 
MEGIKLNLCL LCIFSCDIFA LSNGNIHNVY GSAYSGASAG AYKTLPGSHP YGSKHVPVYK 

        70         80         90        100        110        120 
PMNKIPTPYI SKKSYPAPYK PKGYYPTKRY QPTYGSKTNY PPIYKPIAKK LSSYKAIKTT 

       130        140        150        160        170        180 
YPAYKAKTSY PPSYKHKITY PPTYKPKITY PPTYKQKPSY PPSYKPKTTY PPTYKPKITY 

       190        200        210        220        230        240 
PPTYKRKPSY TPYKPKATYP PTYKPKITYP PTYKRKPSYT PYKPKTTYPP TYKPKISYPS 

       250        260        270        280        290        300 
IYKPKASYVS SYKSKKTYPP TYKPKISYPP TYKPKPSYPP TYKPKVTYPP TYKPKPSYPP 

       310        320        330        340        350        360 
TYKPKITYPP TYKPKPSYPT PYKQKPSYPP IYKSKSSYPT SYKSKKTYPP TYKPKITYPP 

       370        380        390        400        410        420 
TYKPKPSYPP SYKPKKTYSP TYKPKITYPP TYKPKPSYPP SYKPKTTYPP TYKPKISYPP 

       430        440        450        460        470        480 
TYKPKASYVS SYKSKKTYPP TYKPKISYPP TYKPKPSYPP TYKPKITYPP TYKPKPSYPP 

       490        500        510        520        530        540 
TYKPKITYPP TYKRKPSYPT PYKQKPSYPP IYKSKSSYPT SYKSKKTYPP TYKPKITYPP 

       550        560        570        580        590        600 
TYKPKPSYPP SYKPKTTYPP TYKPKIRYPP TYKPKASYPP TYKPKITYPP TYKPKPSYPT 

       610        620        630        640        650        660 
PYKQKPSYPP IYKSKSSYPT AYKSKKTYPP TYKPKITYPP TYKPKPSYPP SYRPKITYPP 

       670        680        690        700        710        720 
TYKPKKSYPQ AYKSKGSYPP SYQPKKTYPP SYKPKKTYPP TYKPKISYPP TYKTKPSYPA 

       730        740        750        760        770        780 
SYKRKTSYPP TYKPKISYPS TYKAKPSYPP TYKPKPSYAS SYKPKIRYPP TYKPKPSYAS 

       790        800        810        820        830        840 
SYKPKIRYPP TYKPKPSYAS SYKPKIRYPP TYKPKPSYAS SYKPKITYPP TYKPKISYPP 

       850        860        870 
TYKPKITYPP TYKPKISYPP AYKPKISYPS QY 

« Hide

References

[1]"Adhesive protein cDNA sequence of the mussel Mytilus coruscus and its evolutionary implications."
Inoue K., Takeuchi Y., Takeyama S., Yamaha E., Yamazaki F., Odo S., Harayama S.
J. Mol. Evol. 43:348-356(1996) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [MRNA].
Tissue: Foot.

Web resources

Protein Spotlight

Sticky business - Issue 2 of September 2001

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
D63777 mRNA. Translation: BAA09850.1.

3D structure databases

ProteinModelPortalQ25434.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Family and domain databases

InterProIPR002964. Adhesive_plaq.
[Graphical view]
PRINTSPR01216. ADHESIVEI.
ProtoNetSearch...

Entry information

Entry nameFP1_MYTCO
AccessionPrimary (citable) accession number: Q25434
Entry history
Integrated into UniProtKB/Swiss-Prot: May 30, 2000
Last sequence update: November 1, 1996
Last modified: February 19, 2014
This is version 61 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)

Relevant documents

Protein Spotlight

Protein Spotlight articles and cited UniProtKB/Swiss-Prot entries