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Q253X7 (Q253X7_CHLFF) Unreviewed, UniProtKB/TrEMBL

Last modified January 25, 2012. Version 45. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Chromosomal replication initiator protein DnaA 2 HAMAP MF_00377
Gene names
Name:dnaA2 HAMAP MF_00377 EMBL BAE81411.1
Ordered Locus Names:CF0639
OrganismChlamydophila felis (strain Fe/C-56) [Complete proteome] [HAMAP]
Taxonomic identifier264202 [NCBI]
Taxonomic lineageBacteria › Chlamydiae › Chlamydiales › Chlamydiaceae › Chlamydia/Chlamydophila group › Chlamydophila

Protein attributes

Sequence length450 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids By similarity. HAMAP MF_00377 RuleBase RU000577

Subcellular location

Cytoplasm By similarity HAMAP MF_00377.

Sequence similarities

Belongs to the DnaA family. HAMAP MF_00377 RuleBase RU004227

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Nucleotide binding156 – 1638ATP By similarity HAMAP MF_00377

Sequences

Sequence LengthMass (Da)Tools
Q253X7 [UniParc].

Last modified April 18, 2006. Version 1.
Checksum: 43112BAF39E7C750

FASTA45051,102
        10         20         30         40         50         60 
MLTCNNCSTW EQFVNYVKTR CSKTAFENWI SPIQIIEETQ EKIRLEVPNI FVQNYLLDNY 

        70         80         90        100        110        120 
KQDLCSFVPL DAQGEPALEF VVAEIKKSPV QPVAPREQKE SPAETFEGSK DFELKLNTAY 

       130        140        150        160        170        180 
RFDNFIEGPS NQFVKSAAVG IAGRPGRSYN PLFIHGGVGL GKTHLLHAVG HYVKEHHKNL 

       190        200        210        220        230        240 
RVHCITTEAF INDLVQHLRL KSIDKMKNFY RSLDLLLVDD IQFLQNRQNF EEEFCNTFET 

       250        260        270        280        290        300 
LINLNKQIVI TSDKPPGQLK LSERIIARME WGLVAHVGIP DLETRVAILQ HKAEQKGLHI 

       310        320        330        340        350        360 
PNEIAFYIAD HIYGNVRQLE GAINKLTAYC RLFGKTLTES IVRDTLKELF RSPSKQKVSV 

       370        380        390        400        410        420 
ESILKSVATV FQVKLQDLKG NSRSKELVLA RQVAMYLAKT LITDSLVAIG SAFGKTHSTV 

       430        440        450 
LYACKTIEQK IEKDETLTRQ ISLCKNHIVG

« Hide

References

[1]"Genome sequence of the cat pathogen, Chlamydophila felis."
Azuma Y., Hirakawa H., Yamashita A., Cai Y., Rahman M.A., Suzuki H., Mitaku S., Toh H., Goto S., Murakami T., Sugi K., Hayashi H., Fukushi H., Hattori M., Kuhara S., Shirai M.
DNA Res. 13:15-23(2006) [PubMed: 16766509] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AP006861 Genomic DNA. Translation: BAE81411.1.
RefSeqYP_515556.1. NC_007899.1.

3D structure databases

ProteinModelPortalQ253X7.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ253X7.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID3959006.
GenomeReviewsGene locus CF0639 in contig AP006861_GR.
KEGGcfe:CF0639.
PATRIC20204925. VBIChlFel51660_0667.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0593.
HOGENOMHBG695666.
OMAWPLCLRR.
PhylomeDBQ253X7.
ProtClustDBPRK00149.

Family and domain databases

HAMAPMF_00377. DnaA_bact.
[Tree]
InterProIPR003593. ATPase_AAA+_core.
IPR001957. Chromosome_initiator_DnaA.
IPR020591. Chromosome_initiator_DnaA-like.
IPR018312. Chromosome_initiator_DnaA_CS.
IPR013159. DnaA_C.
IPR013317. DnaA_Hda.
IPR010921. Trp_repressor/repl_initiator.
[Graphical view]
Gene3DG3DSA:1.10.1750.10. DnaA_C. 1 hit.
KOK02313.
PfamPF00308. Bac_DnaA. 1 hit.
PF08299. Bac_DnaA_C. 1 hit.
[Graphical view]
PRINTSPR00051. DNAA.
SMARTSM00382. AAA. 1 hit.
SM00760. Bac_DnaA_C. 1 hit.
[Graphical view]
SUPFAMSSF48295. Trp_repress_rep. 1 hit.
TIGRFAMsTIGR00362. DnaA. 1 hit.
PROSITEPS01008. DNAA. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameQ253X7_CHLFF
AccessionPrimary (citable) accession number: Q253X7
Entry history
Integrated into UniProtKB/TrEMBL: April 18, 2006
Last sequence update: April 18, 2006
Last modified: January 25, 2012
This is version 45 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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