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Q253M6 (GLGB_CHLFF) Reviewed, UniProtKB/Swiss-Prot

Last modified June 11, 2014. Version 67. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
1,4-alpha-glucan branching enzyme GlgB

EC=2.4.1.18
Alternative name(s):
1,4-alpha-D-glucan:1,4-alpha-D-glucan 6-glucosyl-transferase
Alpha-(1->4)-glucan branching enzyme
Glycogen branching enzyme
Short name=BE
Gene names
Name:glgB
Ordered Locus Names:CF0740
OrganismChlamydophila felis (strain Fe/C-56) [Complete proteome] [HAMAP]
Taxonomic identifier264202 [NCBI]
Taxonomic lineageBacteriaChlamydiaeChlamydialesChlamydiaceaeChlamydia/Chlamydophila groupChlamydophila

Protein attributes

Sequence length721 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position By similarity. HAMAP-Rule MF_00685

Catalytic activity

Transfers a segment of a (1->4)-alpha-D-glucan chain to a primary hydroxy group in a similar glucan chain. HAMAP-Rule MF_00685

Pathway

Glycan biosynthesis; glycogen biosynthesis. HAMAP-Rule MF_00685

Subunit structure

Monomer By similarity. HAMAP-Rule MF_00685

Sequence similarities

Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 7217211,4-alpha-glucan branching enzyme GlgB HAMAP-Rule MF_00685
PRO_0000260644

Sites

Active site4001Nucleophile By similarity
Active site4531Proton donor By similarity

Sequences

Sequence LengthMass (Da)Tools
Q253M6 [UniParc].

Last modified April 18, 2006. Version 1.
Checksum: 72DB46F96E950728

FASTA72182,865
        10         20         30         40         50         60 
MVERILNSED ISLLISGRQS NPHKLLGIIS ENSSQDRIIL FRPGAHSVAV ELQGNIEHAT 

        70         80         90        100        110        120 
HHHSGIFSLT TPKGTLLNDY RIYHQNGLLA HDPYAFSPLW GEIDSFLFHQ GTHYKIYERM 

       130        140        150        160        170        180 
GAIPCDVRGI SGVLFVVWAP HAQRVSVIGD FNFWNGLVNP LRKVSDSGVW ELFIPGLDEG 

       190        200        210        220        230        240 
TLYKWEIVSA SGEILIKTDP YGKGFDVPPL ATSRVINSDR YVWHDAEWME KRSCTQDQPL 

       250        260        270        280        290        300 
SIYEVHVGSW QWQDGRPIGY RGLAERLAQY CKEMSYTHIE LLPITEHPLN ESWGYQVTGY 

       310        320        330        340        350        360 
YAPTWRYGSP EDFQFFVDHL HSEGIGVILD WVPGHFPTDT FALAHFDGEA LYESVDHKEP 

       370        380        390        400        410        420 
LHPHWHTYTF DYRCNEVVNF LLGSALFWLD KMHIDGLRVD AVTSMLYLDY GRKEGEWSPN 

       430        440        450        460        470        480 
IHGGKENLDA IEFLKHFNFI VHKEFPGVMT FAEESTDFPK VTEPINSGGL GFDYKWNLGW 

       490        500        510        520        530        540 
MHDTFRYLKV DPIFRAYHHN DLTFSIWYAF KENYLLPLSH DEVVHGKGSL LQKVPGDTWS 

       550        560        570        580        590        600 
KFAHMRLLLS YQICQPGKKL VFMGGEFAQG REWSPDRSLD WHLLDNPYHA TLHKCVAKMN 

       610        620        630        640        650        660 
SLYRDLPYFW QGDGKQESFR WIDFKDTENN VISYYRLSGN DSNQALLCIH HFSSGYIPSY 

       670        680        690        700        710        720 
VLHCQGIKMC QLLFNSDDIG FGGSGKGNRP PILCIDHGFS WGIDIELPPL ATLIFLVRFS 


N 

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References

[1]"Genome sequence of the cat pathogen, Chlamydophila felis."
Azuma Y., Hirakawa H., Yamashita A., Cai Y., Rahman M.A., Suzuki H., Mitaku S., Toh H., Goto S., Murakami T., Sugi K., Hayashi H., Fukushi H., Hattori M., Kuhara S., Shirai M.
DNA Res. 13:15-23(2006) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: Fe/C-56.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AP006861 Genomic DNA. Translation: BAE81512.1.
RefSeqYP_515657.1. NC_007899.1.

3D structure databases

ProteinModelPortalQ253M6.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING264202.CF0740.

Protein family/group databases

CAZyCBM48. Carbohydrate-Binding Module Family 48.
GH13. Glycoside Hydrolase Family 13.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID3958557.
KEGGcfe:CF0740.
PATRIC20205145. VBIChlFel51660_0776.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0296.
HOGENOMHOG000283037.
KOK00700.
OMAAKLLFMG.
OrthoDBEOG6JX7GT.

Enzyme and pathway databases

BioCycCFEL264202:GJCG-767-MONOMER.
UniPathwayUPA00164.

Family and domain databases

Gene3D2.60.40.10. 2 hits.
2.60.40.1180. 1 hit.
3.20.20.80. 1 hit.
HAMAPMF_00685. GlgB.
InterProIPR006048. A-amylase_b_C.
IPR006407. GlgB.
IPR015902. Glyco_hydro_13.
IPR013780. Glyco_hydro_13_b.
IPR006047. Glyco_hydro_13_cat_dom.
IPR004193. Glyco_hydro_13_N.
IPR013781. Glyco_hydro_catalytic_dom.
IPR017853. Glycoside_hydrolase_SF.
IPR013783. Ig-like_fold.
IPR014756. Ig_E-set.
[Graphical view]
PANTHERPTHR10357. PTHR10357. 1 hit.
PfamPF00128. Alpha-amylase. 1 hit.
PF02806. Alpha-amylase_C. 1 hit.
PF02922. CBM_48. 1 hit.
[Graphical view]
PIRSFPIRSF000463. GlgB. 1 hit.
SUPFAMSSF51445. SSF51445. 1 hit.
SSF81296. SSF81296. 2 hits.
TIGRFAMsTIGR01515. branching_enzym. 1 hit.
ProtoNetSearch...

Entry information

Entry nameGLGB_CHLFF
AccessionPrimary (citable) accession number: Q253M6
Entry history
Integrated into UniProtKB/Swiss-Prot: November 28, 2006
Last sequence update: April 18, 2006
Last modified: June 11, 2014
This is version 67 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways

Glycosyl hydrolases

Classification of glycosyl hydrolase families and list of entries