ID   Q250D6_DESHY            Unreviewed;       663 AA.
AC   Q250D6;
DT   18-APR-2006, integrated into UniProtKB/TrEMBL.
DT   18-APR-2006, sequence version 1.
DT   27-MAR-2024, entry version 85.
DE   RecName: Full=Methyl-accepting chemotaxis sensory transducer {ECO:0008006|Google:ProtNLM};
GN   OrderedLocusNames=DSY0567 {ECO:0000313|EMBL:BAE82356.1};
OS   Desulfitobacterium hafniense (strain Y51).
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Desulfitobacteriaceae;
OC   Desulfitobacterium.
OX   NCBI_TaxID=138119 {ECO:0000313|EMBL:BAE82356.1, ECO:0000313|Proteomes:UP000001946};
RN   [1] {ECO:0000313|EMBL:BAE82356.1, ECO:0000313|Proteomes:UP000001946}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Y51 {ECO:0000313|EMBL:BAE82356.1,
RC   ECO:0000313|Proteomes:UP000001946};
RX   PubMed=16513756; DOI=10.1128/JB.188.6.2262-2274.2006;
RA   Nonaka H., Keresztes G., Shinoda Y., Ikenaga Y., Abe M., Naito K.,
RA   Inatomi K., Furukawa K., Inui M., Yukawa H.;
RT   "Complete genome sequence of the dehalorespiring bacterium
RT   Desulfitobacterium hafniense Y51 and comparison with Dehalococcoides
RT   ethenogenes 195.";
RL   J. Bacteriol. 188:2262-2274(2006).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the methyl-accepting chemotaxis (MCP) protein
CC       family. {ECO:0000256|ARBA:ARBA00029447}.
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DR   EMBL; AP008230; BAE82356.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q250D6; -.
DR   STRING; 138119.DSY0567; -.
DR   KEGG; dsy:DSY0567; -.
DR   eggNOG; COG0840; Bacteria.
DR   HOGENOM; CLU_000445_107_19_9; -.
DR   Proteomes; UP000001946; Chromosome.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR   GO; GO:0004888; F:transmembrane signaling receptor activity; IEA:InterPro.
DR   GO; GO:0006935; P:chemotaxis; IEA:UniProtKB-KW.
DR   GO; GO:0007165; P:signal transduction; IEA:UniProtKB-KW.
DR   CDD; cd06225; HAMP; 1.
DR   CDD; cd11386; MCP_signal; 1.
DR   CDD; cd12912; PDC2_MCP_like; 1.
DR   Gene3D; 6.10.340.10; -; 1.
DR   Gene3D; 1.10.287.950; Methyl-accepting chemotaxis protein; 1.
DR   Gene3D; 3.30.450.20; PAS domain; 1.
DR   InterPro; IPR004090; Chemotax_Me-accpt_rcpt.
DR   InterPro; IPR033479; dCache_1.
DR   InterPro; IPR003660; HAMP_dom.
DR   InterPro; IPR004089; MCPsignal_dom.
DR   PANTHER; PTHR32089:SF92; LYSOZYME-LIKE PROTEIN-RELATED; 1.
DR   PANTHER; PTHR32089; METHYL-ACCEPTING CHEMOTAXIS PROTEIN MCPB; 1.
DR   Pfam; PF02743; dCache_1; 1.
DR   Pfam; PF00672; HAMP; 1.
DR   Pfam; PF00015; MCPsignal; 1.
DR   PRINTS; PR00260; CHEMTRNSDUCR.
DR   SMART; SM00304; HAMP; 1.
DR   SMART; SM00283; MA; 1.
DR   SUPFAM; SSF58104; Methyl-accepting chemotaxis protein (MCP) signaling domain; 1.
DR   PROSITE; PS50111; CHEMOTAXIS_TRANSDUC_2; 1.
DR   PROSITE; PS50885; HAMP; 1.
PE   3: Inferred from homology;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW   Chemotaxis {ECO:0000256|ARBA:ARBA00022500};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001946};
KW   Transducer {ECO:0000256|ARBA:ARBA00023224, ECO:0000256|PROSITE-
KW   ProRule:PRU00284};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        284..303
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          305..358
FT                   /note="HAMP"
FT                   /evidence="ECO:0000259|PROSITE:PS50885"
FT   DOMAIN          377..613
FT                   /note="Methyl-accepting transducer"
FT                   /evidence="ECO:0000259|PROSITE:PS50111"
SQ   SEQUENCE   663 AA;  69910 MW;  C42930EE451BEB50 CRC64;
     MKSLATKFVF LISILLIIVC GSLGFISNHF SSQAVLKEVN QSLEILSRET ALELKNDLER
     QLGLLELLAN LEAIKDPEVP AEEKVRVLKS EIQRAGYIDL GIADLAGNLI NGQGVAGVNI
     ADQDYFKEAI AGKAVASDPK TSKVDDSVIT AYAVPVKHGS QIIGALIATR DGYELSRFTQ
     SIELGGSRAI FVINGQGTAI ANADLEKVKT MDNIFKNAEK NPGLADFAAL QKKMVAGESG
     VGSYTYGGIK KYTGYAPVEG TTWSLAVTAP QKEVMAGVDN LRKILIICSF AFFLIGIVAA
     YGFTRTIVGP LNQLVVKIQE VAKGNLAVKD VEVKSRDEVG LVGDALNTML GSLRDLVNTA
     GDLAEQVAAS SQELTTGAEQ QAKAASEVAN TITNLALGAE NQEKSVDEIT ASVEESSATI
     EQLAVNSNRV AQQTKEAATA SSQGQKSALR AVEQMKNIGE VSVKVQSAVD RLAVSSQEIS
     EINDVISGIA EQTNLLALNA AIEAARAGEQ GRGFAVVAEE VRKLAEQSQA AAKQIAQRIT
     LNQSHITEAV TAIELSSEDI QSGIEVVNTA GGAFEAIDTL MSMVSSQVAE ISTAIQQLAQ
     GSQGIVQAVR SLESITKENM DTSQTVSAAT EEQTASIEEI AASSQNLAAM AESLQVSLSK
     FTV
//