Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

Cysteine proteinase

Gene

cysteine proteinase

Organism
Haemonchus contortus (Barber pole worm)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Hydrolase, Protease, Thiol proteaseSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Cysteine proteinaseImported
Gene namesi
Name:cysteine proteinaseImported
OrganismiHaemonchus contortus (Barber pole worm)Imported
Taxonomic identifieri6289 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaStrongylidaTrichostrongyloideaHaemonchidaeHaemonchinaeHaemonchus

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 1616UniRule annotationAdd
BLAST
Chaini17 – 342326UniRule annotationPRO_5005400161Add
BLAST

Structurei

3D structure databases

ProteinModelPortaliQ25031.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini86 – 336251Pept_C1InterPro annotationAdd
BLAST

Sequence similaritiesi

Belongs to the peptidase C1 family.UniRule annotationSAAS annotation

Keywords - Domaini

SignalUniRule annotation

Family and domain databases

InterProiIPR025661. Pept_asp_AS.
IPR000169. Pept_cys_AS.
IPR025660. Pept_his_AS.
IPR013128. Peptidase_C1A.
IPR000668. Peptidase_C1A_C.
[Graphical view]
PANTHERiPTHR12411. PTHR12411. 1 hit.
PfamiPF00112. Peptidase_C1. 1 hit.
[Graphical view]
PRINTSiPR00705. PAPAIN.
SMARTiSM00645. Pept_C1. 1 hit.
[Graphical view]
PROSITEiPS00640. THIOL_PROTEASE_ASN. 1 hit.
PS00139. THIOL_PROTEASE_CYS. 1 hit.
PS00639. THIOL_PROTEASE_HIS. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q25031-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MYLVFTLCAY LCAASGASIN AAQEIPLEAQ TLTGEPLVAY LRKNQNLFEV
60 70 80 90 100
NSEPTPNFEQ KIMDIKFKNQ KLNFVVKNDP EPNEDIPEEY DPREKFKCST
110 120 130 140 150
FYIRDQANCG SCWAVSTAAA ISDRICIATN GEKQVNISST DILTCCNPQC
160 170 180 190 200
GFGCGGGWSI RAWEYFVYEG VVSGGEYLTK GVCRPYPIHP CGHHGNDTYY
210 220 230 240 250
GECPREAATP PCKKKCQPGY KKIFRMDKRQ GKVAYGVEPK EEAIQREILR
260 270 280 290 300
HGPVVASFAV YEDFSLYKTG VYKHTAGALR GYHAVKMMGW GVDSKTKAKY
310 320 330 340
WLIANSWHND WGENGYFRFI RGINDCEIED TVAAGIVDVD SL
Length:342
Mass (Da):38,315
Last modified:November 1, 1996 - v1
Checksum:iF22A7B3EC4E9D280
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M80386 mRNA. Translation: AAA29177.1.
PIRiC48435.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M80386 mRNA. Translation: AAA29177.1.
PIRiC48435.

3D structure databases

ProteinModelPortaliQ25031.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Family and domain databases

InterProiIPR025661. Pept_asp_AS.
IPR000169. Pept_cys_AS.
IPR025660. Pept_his_AS.
IPR013128. Peptidase_C1A.
IPR000668. Peptidase_C1A_C.
[Graphical view]
PANTHERiPTHR12411. PTHR12411. 1 hit.
PfamiPF00112. Peptidase_C1. 1 hit.
[Graphical view]
PRINTSiPR00705. PAPAIN.
SMARTiSM00645. Pept_C1. 1 hit.
[Graphical view]
PROSITEiPS00640. THIOL_PROTEASE_ASN. 1 hit.
PS00139. THIOL_PROTEASE_CYS. 1 hit.
PS00639. THIOL_PROTEASE_HIS. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Cloning and sequence comparisons of four distinct cysteine proteases expressed by Haemonchus contortus adult worms."
    Pratt D., Armes L.G., Hageman R., Reynolds V., Boisvenue R.J., Cox G.N.
    Mol. Biochem. Parasitol. 51:209-218(1992) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.

Entry informationi

Entry nameiQ25031_HAECO
AccessioniPrimary (citable) accession number: Q25031
Entry historyi
Integrated into UniProtKB/TrEMBL: November 1, 1996
Last sequence update: November 1, 1996
Last modified: May 11, 2016
This is version 67 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.