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Protein
Submitted name:

Cysteine proteinase

Gene
N/A
Organism
Haemonchus contortus (Barber pole worm)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Cysteine proteinaseImported
OrganismiHaemonchus contortus (Barber pole worm)Imported
Taxonomic identifieri6289 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaStrongylidaTrichostrongyloideaHaemonchidaeHaemonchinaeHaemonchus

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 1616UniRule annotationAdd
BLAST
Chaini17 – 350334UniRule annotationPRO_5005400159Add
BLAST

Structurei

3D structure databases

ProteinModelPortaliQ25026.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini94 – 330237Pept_C1InterPro annotationAdd
BLAST

Sequence similaritiesi

Belongs to the peptidase C1 family.UniRule annotationSAAS annotation

Keywords - Domaini

SignalUniRule annotation

Family and domain databases

InterProiIPR000169. Pept_cys_AS.
IPR025660. Pept_his_AS.
IPR013128. Peptidase_C1A.
IPR000668. Peptidase_C1A_C.
[Graphical view]
PANTHERiPTHR12411. PTHR12411. 1 hit.
PfamiPF00112. Peptidase_C1. 1 hit.
[Graphical view]
PRINTSiPR00705. PAPAIN.
SMARTiSM00645. Pept_C1. 1 hit.
[Graphical view]
PROSITEiPS00139. THIOL_PROTEASE_CYS. 1 hit.
PS00639. THIOL_PROTEASE_HIS. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q25026-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLFLLIFSVF FAIASSQEVH TIEELLAQQT SDDSDTLTGE ALVEYVNKHQ
60 70 80 90 100
SFSRLNTSKA EERMAHLMKT DYIRNARKLY KVKKAEEQTT NEDIPESFDS
110 120 130 140 150
RIVWKNCSSI TYVRDQSRCG SCWAVSAAST MSDRICVQTK GKLQTILSDT
160 170 180 190 200
DILSCCGRMC GDGCEGGYDH LAWEWVQRFG VVTGGPYQQK GVCRPYAFHP
210 220 230 240 250
CGLHHGRRYD CPWDHSFSTP ACKPYCQFGY GKRYEKDKFF VKSTYILDND
260 270 280 290 300
EKVIQREMMK NGPVQAAFIT YEDFSPYKGG IYVHVKGRER GAHAVKLIGW
310 320 330 340 350
GVENGTKYWT VANSWHDDWG GKRFLPYSTW SESLRVRIVC RFRRIQNLIG
Length:350
Mass (Da):40,183
Last modified:August 1, 1998 - v2
Checksum:i0FE2DA1AAED9CE6F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z69343 mRNA. Translation: CAA93276.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z69343 mRNA. Translation: CAA93276.1.

3D structure databases

ProteinModelPortaliQ25026.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Family and domain databases

InterProiIPR000169. Pept_cys_AS.
IPR025660. Pept_his_AS.
IPR013128. Peptidase_C1A.
IPR000668. Peptidase_C1A_C.
[Graphical view]
PANTHERiPTHR12411. PTHR12411. 1 hit.
PfamiPF00112. Peptidase_C1. 1 hit.
[Graphical view]
PRINTSiPR00705. PAPAIN.
SMARTiSM00645. Pept_C1. 1 hit.
[Graphical view]
PROSITEiPS00139. THIOL_PROTEASE_CYS. 1 hit.
PS00639. THIOL_PROTEASE_HIS. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Skuce P.J.
    Submitted (DEC-1997) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: MoredunImported.
    Tissue: Whole wormImported.
  2. "Molecular cloning and characterization of gut-derived cysteine proteinases associated with a host protective extract from Haemonchus contortus."
    Skuce P.J., Redmond D.L., Liddell S., Stewart E.M., Newlands G.F., Smith W.D., Knox D.P.
    Parasitology 119:405-412(1999) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: MoredunImported.
    Tissue: Whole wormImported.

Entry informationi

Entry nameiQ25026_HAECO
AccessioniPrimary (citable) accession number: Q25026
Entry historyi
Integrated into UniProtKB/TrEMBL: November 1, 1996
Last sequence update: August 1, 1998
Last modified: May 11, 2016
This is version 62 of the entry and version 2 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.