Skip Header

Contribute Send feedback
Read comments (?) or add your own

Q24XT7 (Q24XT7_DESHY) Unreviewed, UniProtKB/TrEMBL

Last modified May 1, 2013. Version 59. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry infoCustomize order
to top of pageNames·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein namesRecommended name:
Acetolactate synthase RuleBase RU003591
EC=2.2.1.6 RuleBase RU003591
Gene names
Ordered Locus Names:DSY1366
OrganismDesulfitobacterium hafniense (strain Y51) [Complete proteome] [HAMAP]
Taxonomic identifier138119 [NCBI]
Taxonomic lineageBacteria › Firmicutes › Clostridia › Clostridiales › Peptococcaceae › Desulfitobacterium ›

Protein attributes

Sequence length561 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

2 pyruvate = 2-acetolactate + CO2.

Cofactor

Binds 1 magnesium ion per subunit By similarity.

Binds 1 thiamine pyrophosphate per subunit By similarity.

Pathway

Amino-acid biosynthesis; L-isoleucine biosynthesis; L-isoleucine from 2-oxobutanoate: step 1/4.

Amino-acid biosynthesis; L-valine biosynthesis; L-valine from pyruvate: step 1/4.

Sequence similarities

Belongs to the TPP enzyme family. RuleBase RU003702

Sequences

Sequence LengthMass (Da)Tools
Q24XT7 [UniParc].

Last modified April 18, 2006. Version 1.
Checksum: 94ACC0EB4289EF5B

FASTA56160,138
        10         20         30         40         50         60 
MGNEKESTTY ATGAALLLDS LVQEGVEVMF GYPGGAVLPI YDALINSPIR HLLPRHEQTA 

        70         80         90        100        110        120 
IHAADAFARV SGKVGVCLAT SGPGATNLVT GIANAYMDSI PVVILTGQVP TSLLGTDSFQ 

       130        140        150        160        170        180 
EVDITGITLP ITKHSYLVKD PRQIPRIVKE AFYIASTGRP GPVLIDLPKN VLAATDVRPA 

       190        200        210        220        230        240 
PAELNLKSYK YFTKGNAGQI EEAARVIAQS QRPVLYAGGG VITAGASEIL QQVVERANLP 

       250        260        270        280        290        300 
VVTTLMGIGS LPTNHPNVLG MVGMHGTVTA NYAVDDCDLL IAIGVRFDDR VTSGLGHRFA 

       310        320        330        340        350        360 
TKAKIIHIDI DPAEIGKVAR TKVPIVGNAK LVLEELLSKV SKPEISPWWE QIRLWQEEKL 

       370        380        390        400        410        420 
KTDNPNLNPQ VIIETLGEIA GEETIVTTDV GQHQMWAAQG YPVPAPRHFI TSGGLGTMGF 

       430        440        450        460        470        480 
GLPAALGAQV AAPESTVFLV TGDGSFQMSI QELATAVQYQ LPVKIILMNN GVLGMVRQLQ 

       490        500        510        520        530        540 
MVFCDERYSQ IQLTANPDFI KIAEAYGIRG IRVTETSEVR NALLEAINHP GPVLMDFIIS 

       550        560 
EDEVVSPMVP PGKGLTEMLG W

« Hide

References

[1]"Complete genome sequence of the dehalorespiring bacterium Desulfitobacterium hafniense Y51 and comparison with Dehalococcoides ethenogenes 195."
Nonaka H., Keresztes G., Shinoda Y., Ikenaga Y., Abe M., Naito K., Inatomi K., Furukawa K., Inui M., Yukawa H.
J. Bacteriol. 188:2262-2274(2006) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: Y51.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AP008230 Genomic DNA. Translation: BAE83155.1.
RefSeqYP_517599.1. NC_007907.1.

3D structure databases

ProteinModelPortalQ24XT7.
ModBaseSearch...

Protein-protein interaction databases

STRING138119.DSY1366.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaBAE83155; BAE83155; DSY1366.
GeneID3953996.
KEGGdsy:DSY1366.
PATRIC21671117. VBIDesHaf65307_1523.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0028.
HOGENOMHOG000258448.
KOK01652.
OMAERYEYVY.
ProtClustDBCLSK2465803.

Enzyme and pathway databases

BioCycDHAF138119:GHT5-1367-MONOMER.
UniPathwayUPA00047; UER00055.
UPA00049; UER00059.

Family and domain databases

InterProIPR012846. Acetolactate_synth_lsu.
IPR012000. Thiamin_PyroP_enz_cen_dom.
IPR012001. Thiamin_PyroP_enz_TPP-bd_dom.
IPR000399. TPP-bd_CS.
IPR011766. TPP_enzyme-bd_C.
[Graphical view]
PANTHERPTHR18968:SF13. PTHR18968:SF13. 1 hit.
PfamPF02775. TPP_enzyme_C. 1 hit.
PF00205. TPP_enzyme_M. 1 hit.
PF02776. TPP_enzyme_N. 1 hit.
[Graphical view]
TIGRFAMsTIGR00118. acolac_lg. 1 hit.
PROSITEPS00187. TPP_ENZYMES. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameQ24XT7_DESHY
AccessionPrimary (citable) accession number: Q24XT7
Entry history
Integrated into UniProtKB/TrEMBL: April 18, 2006
Last sequence update: April 18, 2006
Last modified: May 1, 2013
This is version 59 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry info