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Q24VW9 (G6PI_DESHY) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 37. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Glucose-6-phosphate isomerase
Short name=GPI
EC=5.3.1.9
Alternative name(s):
Phosphoglucose isomerase
Short name=PGI
Phosphohexose isomerase
Short name=PHI
Gene names
Name:pgi
Ordered Locus Names:DSY2034
OrganismDesulfitobacterium hafniense (strain Y51) [Complete proteome] [HAMAP]
Taxonomic identifier138119 [NCBI]
Taxonomic lineageBacteria › Firmicutes › Clostridia › Clostridiales › Peptococcaceae › Desulfitobacterium

Protein attributes

Sequence length533 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

D-glucose 6-phosphate = D-fructose 6-phosphate. HAMAP MF_00473

Pathway

Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 2/4. HAMAP MF_00473

Subcellular location

Cytoplasm By similarity HAMAP MF_00473.

Sequence similarities

Belongs to the GPI family.

Ontologies

Keywords
   Biological processGluconeogenesis
Glycolysis
   Cellular componentCytoplasm
   Molecular functionIsomerase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processgluconeogenesis

Inferred from electronic annotation. Source: UniProtKB-KW

glycolysis

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functionglucose-6-phosphate isomerase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 533533Glucose-6-phosphate isomerase HAMAP MF_00473
PRO_0000252618

Sites

Active site3221Proton donor By similarity
Active site3511 By similarity
Active site4551 By similarity

Sequences

Sequence LengthMass (Da)Tools
Q24VW9 [UniParc].

Last modified April 18, 2006. Version 1.
Checksum: A44A5D9D6FEF1AF6

FASTA53359,487
        10         20         30         40         50         60 
MVTITSWKRF KEYLYYDQEL GLLLDISRMN FSAEFLRSMA EPMREAYHQL QLLEKGALAN 

        70         80         90        100        110        120 
PDEGRMVGHY WLRNPDLAPT EEIVQDIKET LKEILDFAEQ IHSGRLQGEK GNPFRNILLV 

       130        140        150        160        170        180 
GVGGSILGPR FVADALASSR DKMKAFFIDN GDPDGIDRVL SRIGEELPAT LCLIISKSGG 

       190        200        210        220        230        240 
TIETRNGMLE VRRAYKEAGL SFPDHAVAIT QRGSQLDKLS QKEGWLRAFP MWDWVGGRTS 

       250        260        270        280        290        300 
LLSAVGLLSL ALQGIDVAGL LQGAKDCDGR TRRPDTLDNP GALLALMWYY STQGQGGKQM 

       310        320        330        340        350        360 
VVLPYKDRLE LFTKYLQQLI MESLGKEKNL QGETVHQGIT VYGNKGSSDQ HSYLQQLLEG 

       370        380        390        400        410        420 
PDNFFVTFIE VLKDRQGPST YMEENSTSGE YLQAFLLGTR EALTQKGRES LTITVKEVNA 

       430        440        450        460        470        480 
YTIGVLIALF ERAVSIYALL VGINAYHQPA VEMGKKAAGQ AIQLKNNIVE FLKSHPGKKF 

       490        500        510        520        530 
SVSELALAIQ EEEHQEMVFK LLLHLTTNPE HGVNMEPGEP WPESRFFVGG PIS

« Hide

References

[1]"Complete genome sequence of the dehalorespiring bacterium Desulfitobacterium hafniense Y51 and comparison with Dehalococcoides ethenogenes 195."
Nonaka H., Keresztes G., Shinoda Y., Ikenaga Y., Abe M., Naito K., Inatomi K., Furukawa K., Inui M., Yukawa H.
J. Bacteriol. 188:2262-2274(2006) [PubMed: 16513756] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: Y51.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AP008230 Genomic DNA. Translation: BAE83823.1.
RefSeqYP_518267.1. NC_007907.1.

3D structure databases

ProteinModelPortalQ24VW9.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ24VW9.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID3956131.
GenomeReviewsGene locus DSY2034 in contig AP008230_GR.
KEGGdsy:DSY2034.
NMPDRfig|138119.3.peg.2057.
PATRIC21672667. VBIDesHaf65307_2274.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0166.
HOGENOMHBG285902.
OMARTSITSA.
ProtClustDBPRK14096.

Enzyme and pathway databases

BioCycDHAF138119:DSY2034-MONOMER.

Family and domain databases

HAMAPMF_00473. G6P_isomerase.
[Tree]
InterProIPR001672. G6P_Isomerase.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view]
KOK01810.
PANTHERPTHR11469. G6P_Isomerase. 1 hit.
PfamPF00342. PGI. 1 hit.
[Graphical view]
PRINTSPR00662. G6PISOMERASE.
PROSITEPS00765. P_GLUCOSE_ISOMERASE_1. False negative.
PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameG6PI_DESHY
AccessionPrimary (citable) accession number: Q24VW9
Entry history
Integrated into UniProtKB/Swiss-Prot: October 17, 2006
Last sequence update: April 18, 2006
Last modified: January 25, 2012
This is version 37 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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