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Protein

Glucose-6-phosphate isomerase

Gene

pgi

Organism
Desulfitobacterium hafniense (strain Y51)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

D-glucose 6-phosphate = D-fructose 6-phosphate.UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei322 – 3221Proton donorUniRule annotation
Active sitei351 – 3511UniRule annotation
Active sitei455 – 4551UniRule annotation

GO - Molecular functioni

  1. glucose-6-phosphate isomerase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. gluconeogenesis Source: UniProtKB-HAMAP
  2. glycolytic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Keywords - Biological processi

Gluconeogenesis, Glycolysis

Enzyme and pathway databases

BioCyciDHAF138119:GHT5-2093-MONOMER.
UniPathwayiUPA00109; UER00181.

Names & Taxonomyi

Protein namesi
Recommended name:
Glucose-6-phosphate isomeraseUniRule annotation (EC:5.3.1.9UniRule annotation)
Short name:
GPIUniRule annotation
Alternative name(s):
Phosphoglucose isomeraseUniRule annotation
Short name:
PGIUniRule annotation
Phosphohexose isomeraseUniRule annotation
Short name:
PHIUniRule annotation
Gene namesi
Name:pgiUniRule annotation
Ordered Locus Names:DSY2034
OrganismiDesulfitobacterium hafniense (strain Y51)
Taxonomic identifieri138119 [NCBI]
Taxonomic lineageiBacteriaFirmicutesClostridiaClostridialesPeptococcaceaeDesulfitobacterium
ProteomesiUP000001946 Componenti: Chromosome

Subcellular locationi

Cytoplasm UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 533533Glucose-6-phosphate isomerasePRO_0000252618Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi138119.DSY2034.

Family & Domainsi

Sequence similaritiesi

Belongs to the GPI family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0166.
HOGENOMiHOG000131425.
KOiK01810.
OMAiRQVGHYW.
OrthoDBiEOG64R61J.

Family and domain databases

HAMAPiMF_00473. G6P_isomerase.
InterProiIPR001672. G6P_Isomerase.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view]
PANTHERiPTHR11469. PTHR11469. 1 hit.
PfamiPF00342. PGI. 1 hit.
[Graphical view]
PRINTSiPR00662. G6PISOMERASE.
PROSITEiPS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q24VW9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVTITSWKRF KEYLYYDQEL GLLLDISRMN FSAEFLRSMA EPMREAYHQL
60 70 80 90 100
QLLEKGALAN PDEGRMVGHY WLRNPDLAPT EEIVQDIKET LKEILDFAEQ
110 120 130 140 150
IHSGRLQGEK GNPFRNILLV GVGGSILGPR FVADALASSR DKMKAFFIDN
160 170 180 190 200
GDPDGIDRVL SRIGEELPAT LCLIISKSGG TIETRNGMLE VRRAYKEAGL
210 220 230 240 250
SFPDHAVAIT QRGSQLDKLS QKEGWLRAFP MWDWVGGRTS LLSAVGLLSL
260 270 280 290 300
ALQGIDVAGL LQGAKDCDGR TRRPDTLDNP GALLALMWYY STQGQGGKQM
310 320 330 340 350
VVLPYKDRLE LFTKYLQQLI MESLGKEKNL QGETVHQGIT VYGNKGSSDQ
360 370 380 390 400
HSYLQQLLEG PDNFFVTFIE VLKDRQGPST YMEENSTSGE YLQAFLLGTR
410 420 430 440 450
EALTQKGRES LTITVKEVNA YTIGVLIALF ERAVSIYALL VGINAYHQPA
460 470 480 490 500
VEMGKKAAGQ AIQLKNNIVE FLKSHPGKKF SVSELALAIQ EEEHQEMVFK
510 520 530
LLLHLTTNPE HGVNMEPGEP WPESRFFVGG PIS
Length:533
Mass (Da):59,487
Last modified:April 18, 2006 - v1
Checksum:iA44A5D9D6FEF1AF6
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP008230 Genomic DNA. Translation: BAE83823.1.
RefSeqiYP_518267.1. NC_007907.1.

Genome annotation databases

EnsemblBacteriaiBAE83823; BAE83823; DSY2034.
KEGGidsy:DSY2034.
PATRICi21672667. VBIDesHaf65307_2274.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP008230 Genomic DNA. Translation: BAE83823.1.
RefSeqiYP_518267.1. NC_007907.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi138119.DSY2034.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiBAE83823; BAE83823; DSY2034.
KEGGidsy:DSY2034.
PATRICi21672667. VBIDesHaf65307_2274.

Phylogenomic databases

eggNOGiCOG0166.
HOGENOMiHOG000131425.
KOiK01810.
OMAiRQVGHYW.
OrthoDBiEOG64R61J.

Enzyme and pathway databases

UniPathwayiUPA00109; UER00181.
BioCyciDHAF138119:GHT5-2093-MONOMER.

Family and domain databases

HAMAPiMF_00473. G6P_isomerase.
InterProiIPR001672. G6P_Isomerase.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view]
PANTHERiPTHR11469. PTHR11469. 1 hit.
PfamiPF00342. PGI. 1 hit.
[Graphical view]
PRINTSiPR00662. G6PISOMERASE.
PROSITEiPS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Complete genome sequence of the dehalorespiring bacterium Desulfitobacterium hafniense Y51 and comparison with Dehalococcoides ethenogenes 195."
    Nonaka H., Keresztes G., Shinoda Y., Ikenaga Y., Abe M., Naito K., Inatomi K., Furukawa K., Inui M., Yukawa H.
    J. Bacteriol. 188:2262-2274(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Y51.

Entry informationi

Entry nameiG6PI_DESHY
AccessioniPrimary (citable) accession number: Q24VW9
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 17, 2006
Last sequence update: April 18, 2006
Last modified: April 1, 2015
This is version 59 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.