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Q24VW3 (GLGB_DESHY) Reviewed, UniProtKB/Swiss-Prot

Last modified June 11, 2014. Version 68. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
1,4-alpha-glucan branching enzyme GlgB

EC=2.4.1.18
Alternative name(s):
1,4-alpha-D-glucan:1,4-alpha-D-glucan 6-glucosyl-transferase
Alpha-(1->4)-glucan branching enzyme
Glycogen branching enzyme
Short name=BE
Gene names
Name:glgB
Ordered Locus Names:DSY2040
OrganismDesulfitobacterium hafniense (strain Y51) [Complete proteome] [HAMAP]
Taxonomic identifier138119 [NCBI]
Taxonomic lineageBacteriaFirmicutesClostridiaClostridialesPeptococcaceaeDesulfitobacterium

Protein attributes

Sequence length632 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position By similarity. HAMAP-Rule MF_00685

Catalytic activity

Transfers a segment of a (1->4)-alpha-D-glucan chain to a primary hydroxy group in a similar glucan chain. HAMAP-Rule MF_00685

Pathway

Glycan biosynthesis; glycogen biosynthesis. HAMAP-Rule MF_00685

Subunit structure

Monomer By similarity. HAMAP-Rule MF_00685

Sequence similarities

Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 6326321,4-alpha-glucan branching enzyme GlgB HAMAP-Rule MF_00685
PRO_0000260651

Sites

Active site3101Nucleophile By similarity
Active site3631Proton donor By similarity

Sequences

Sequence LengthMass (Da)Tools
Q24VW3 [UniParc].

Last modified April 18, 2006. Version 1.
Checksum: 509D7493EDB215FE

FASTA63273,225
        10         20         30         40         50         60 
MQSKIQKDSP LLTQEEMYLF NCGEFYYSYR KFGAHFLEHK GRWGTYFAVW APQARQVSVV 

        70         80         90        100        110        120 
GDFNGWCGMN HSLQKWEEQG IWTLFIPGLP TGEIYKYEIL TSSGESVLKA DPYAFFSEVR 

       130        140        150        160        170        180 
PHTASVIYSL EDYSWGDQAW LAQRKTRNPK VLPLSSYEIH LGSWRRTEDG RFLNYAQLVT 

       190        200        210        220        230        240 
VLIPYVKSLG YTHIEILPLM EHPYDGSWGY QITGFYACTS RYGTPHDLMY LIDQCHQAGI 

       250        260        270        280        290        300 
GVILDWVPGH FCMDAHGLGK FDGSPLYERE VHEQWGTYKF DYSRSEVRSF LISNAVFWLD 

       310        320        330        340        350        360 
VFHVDGLRVD GVSSMLYLDY GKAKGAWQPN RYGGRENLEA VGFIKQLNAT LHGLYPDALL 

       370        380        390        400        410        420 
IAEEATDWQG VTGPLDQEGL GFTFKWNMGW MNDTLRYIGL DFPERRSFHQ LLTFPMMYAY 

       430        440        450        460        470        480 
AESYILPLSH DEVVHGKKSL LDKMPGDYGQ KFAGLRGLTT YFMTSPGKKL LFMGGEIPQF 

       490        500        510        520        530        540 
IEWREDRELD WFLMDYEMHR KYHGFVQQLN GLYLREKALW EIDGDWTGFE WIDVHNHEQG 

       550        560        570        580        590        600 
VIVFCRKGKS FQDRLVVLIN FQPYNYERYR IGVEMAKGYR EILNTDSTDF GGWGMTNPGL 

       610        620        630 
LKVEGVPWHG REFSLEIRVP ALGAMILKPE LA 

« Hide

References

[1]"Complete genome sequence of the dehalorespiring bacterium Desulfitobacterium hafniense Y51 and comparison with Dehalococcoides ethenogenes 195."
Nonaka H., Keresztes G., Shinoda Y., Ikenaga Y., Abe M., Naito K., Inatomi K., Furukawa K., Inui M., Yukawa H.
J. Bacteriol. 188:2262-2274(2006) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: Y51.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AP008230 Genomic DNA. Translation: BAE83829.1.
RefSeqYP_518273.1. NC_007907.1.

3D structure databases

ProteinModelPortalQ24VW3.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING138119.DSY2040.

Protein family/group databases

CAZyCBM48. Carbohydrate-Binding Module Family 48.
GH13. Glycoside Hydrolase Family 13.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaBAE83829; BAE83829; DSY2040.
GeneID3956137.
KEGGdsy:DSY2040.
PATRIC21672679. VBIDesHaf65307_2280.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0296.
HOGENOMHOG000283037.
KOK00700.
OMAAKLLFMG.
OrthoDBEOG6JX7GT.

Enzyme and pathway databases

BioCycDHAF138119:GHT5-2099-MONOMER.
UniPathwayUPA00164.

Family and domain databases

Gene3D2.60.40.10. 1 hit.
2.60.40.1180. 1 hit.
3.20.20.80. 1 hit.
HAMAPMF_00685. GlgB.
InterProIPR006048. A-amylase_b_C.
IPR006407. GlgB.
IPR015902. Glyco_hydro_13.
IPR013780. Glyco_hydro_13_b.
IPR006047. Glyco_hydro_13_cat_dom.
IPR004193. Glyco_hydro_13_N.
IPR013781. Glyco_hydro_catalytic_dom.
IPR017853. Glycoside_hydrolase_SF.
IPR013783. Ig-like_fold.
IPR014756. Ig_E-set.
[Graphical view]
PANTHERPTHR10357. PTHR10357. 1 hit.
PfamPF00128. Alpha-amylase. 1 hit.
PF02806. Alpha-amylase_C. 1 hit.
PF02922. CBM_48. 1 hit.
[Graphical view]
PIRSFPIRSF000463. GlgB. 1 hit.
SUPFAMSSF51445. SSF51445. 1 hit.
SSF81296. SSF81296. 1 hit.
TIGRFAMsTIGR01515. branching_enzym. 1 hit.
ProtoNetSearch...

Entry information

Entry nameGLGB_DESHY
AccessionPrimary (citable) accession number: Q24VW3
Entry history
Integrated into UniProtKB/Swiss-Prot: November 28, 2006
Last sequence update: April 18, 2006
Last modified: June 11, 2014
This is version 68 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways

Glycosyl hydrolases

Classification of glycosyl hydrolase families and list of entries