Reviewed, UniProtKB/Swiss-Prot Q24SW9 (SYGA_DESHY)

Names and origin

Protein names

Recommended name:
    Glycyl-tRNA synthetase alpha subunit
    EC=6.1.1.14
Alternative name(s):
    Glycine--tRNA ligase alpha subunit
      Short name=GlyRS

Gene names

Name:	glyQ
Ordered Locus Names:	DSY3084

Organism

Desulfitobacterium hafniense (strain Y51) [Complete proteome] [HAMAP]

Taxonomic identifier

138119 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Clostridia › Clostridiales › Peptococcaceae › Desulfitobacterium

Protein attributes

Sequence length	296 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	ATP + glycine + tRNA(Gly) = AMP + diphosphate + glycyl-tRNA(Gly). HAMAP MF_00254
Subunit structure	Tetramer of two alpha and two beta subunits By similarity.
Subcellular location	Cytoplasm. HAMAP MF_00254
Sequence similarities	Belongs to the class-II aminoacyl-tRNA synthetase family.

Ontologies

Keywords
Biological process	Protein biosynthesis
Cellular component	Cytoplasm
Ligand	ATP-binding Nucleotide-binding
Molecular function	Aminoacyl-tRNA synthetase Ligase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	glycyl-tRNA aminoacylation Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: HAMAP glycine-tRNA ligase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 296	296	Glycyl-tRNA synthetase alpha subunit HAMAP MF_00254		PRO_1000047414

Sequences

	Sequence		Length	Mass (Da)
	Q24SW9-1 [UniParc]. Last modified April 18, 2006. Version 1. Checksum: 894B2EF98BFB1F10	FASTA	296	34,342
	10 20 30 40 50 60 MKFQDMILSL NQFWGEQGCI IAQPYDMEKG AGTFNPNTFL RALGPEPWKV AYIEPSRRPT 70 80 90 100 110 120 DGRYGENPNR LQHYFQYQVI IKPSPDNIQE LYLQSLERLG VNPKEHDIRF VEDNWESPTL 130 140 150 160 170 180 GAWGLGWEVW LDGMEVTQFT YFQQCGGIDC KPVCAEITYG LERLAMYIQN KESVYDIEYV 190 200 210 220 230 240 GDITYGDIYL QNEIDYSYYN FRAADVEALQ AWFEMYEKEA IRIAEKGLVL PAYDYVLKCS 250 260 270 280 290 HTFNLLDARG AISVTERTGY IARVRNLARL CAQAYVEQRE RLGYPLLKEQ SGKEAE

References

[1]

"Complete genome sequence of the dehalorespiring bacterium Desulfitobacterium hafniense Y51 and comparison with Dehalococcoides ethenogenes 195." Nonaka H., Keresztes G., Shinoda Y., Ikenaga Y., Abe M., Naito K., Inatomi K., Furukawa K., Inui M., Yukawa H. J. Bacteriol. 188:2262-2274(2006) [PubMed: 16513756] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	AP008230 Genomic DNA. Translation: BAE84873.1.
RefSeq	YP_519317.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	Q24SW9.
Genome annotation databases
GeneID	3955561.
GenomeReviews	Gene locus DSY3084 in contig AP008230_GR.
KEGG	dsy:DSY3084.
NMPDR	fig|138119.3.peg.4446.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q24SW9.
OMA	CRRPTDG.
Enzyme and pathway databases
BioCyc	DHAF138119:DSY3084-MON.
Family and domain databases
HAMAP	MF_00254. [Tree]
InterPro	IPR006194. Gly-tRNA-synth_II_heterodimer. IPR002310. Gly-tRNA_synth_IIc_asu. [Graphical view]
Pfam	PF02091. tRNA-synt_2e. 1 hit. [Graphical view]
PRINTS	PR01044. TRNASYNTHGA.
ProDom	PD006985. tRNA_synt_2e. 1 hit. [Graphical view] [Entries sharing at least one domain]
TIGRFAMs	TIGR00388. glyQ. 1 hit.
PROSITE	PS50861. AA_TRNA_LIGASE_II_GLYAB. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

SYGA_DESHY

Accession

Primary (citable) accession number: Q24SW9

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
Last sequence update:	April 18, 2006
Last modified:	November 3, 2009
This is version 23 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)