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Protein

Glycine--tRNA ligase alpha subunit

Gene

glyQ

Organism
Desulfitobacterium hafniense (strain Y51)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + glycine + tRNA(Gly) = AMP + diphosphate + glycyl-tRNA(Gly).UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Aminoacyl-tRNA synthetase, Ligase

Keywords - Biological processi

Protein biosynthesis

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciDHAF138119:GHT5-3151-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Glycine--tRNA ligase alpha subunitUniRule annotation (EC:6.1.1.14UniRule annotation)
Alternative name(s):
Glycyl-tRNA synthetase alpha subunitUniRule annotation
Short name:
GlyRSUniRule annotation
Gene namesi
Name:glyQUniRule annotation
Ordered Locus Names:DSY3084
OrganismiDesulfitobacterium hafniense (strain Y51)
Taxonomic identifieri138119 [NCBI]
Taxonomic lineageiBacteriaFirmicutesClostridiaClostridialesPeptococcaceaeDesulfitobacterium
Proteomesi
  • UP000001946 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 296296Glycine--tRNA ligase alpha subunitPRO_1000047414Add
BLAST

Interactioni

Subunit structurei

Tetramer of two alpha and two beta subunits.UniRule annotation

Protein-protein interaction databases

STRINGi138119.DSY3084.

Structurei

3D structure databases

ProteinModelPortaliQ24SW9.
SMRiQ24SW9. Positions 1-277.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the class-II aminoacyl-tRNA synthetase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4108HMW. Bacteria.
COG0752. LUCA.
HOGENOMiHOG000264291.
KOiK01878.
OMAiLGSYYQF.
OrthoDBiEOG661H9S.

Family and domain databases

HAMAPiMF_00254. Gly_tRNA_synth_alpha.
InterProiIPR006194. Gly-tRNA-synth_heterodimer.
IPR002310. Gly-tRNA_ligase_asu.
[Graphical view]
PfamiPF02091. tRNA-synt_2e. 1 hit.
[Graphical view]
PRINTSiPR01044. TRNASYNTHGA.
TIGRFAMsiTIGR00388. glyQ. 1 hit.
PROSITEiPS50861. AA_TRNA_LIGASE_II_GLYAB. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q24SW9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKFQDMILSL NQFWGEQGCI IAQPYDMEKG AGTFNPNTFL RALGPEPWKV
60 70 80 90 100
AYIEPSRRPT DGRYGENPNR LQHYFQYQVI IKPSPDNIQE LYLQSLERLG
110 120 130 140 150
VNPKEHDIRF VEDNWESPTL GAWGLGWEVW LDGMEVTQFT YFQQCGGIDC
160 170 180 190 200
KPVCAEITYG LERLAMYIQN KESVYDIEYV GDITYGDIYL QNEIDYSYYN
210 220 230 240 250
FRAADVEALQ AWFEMYEKEA IRIAEKGLVL PAYDYVLKCS HTFNLLDARG
260 270 280 290
AISVTERTGY IARVRNLARL CAQAYVEQRE RLGYPLLKEQ SGKEAE
Length:296
Mass (Da):34,342
Last modified:April 18, 2006 - v1
Checksum:i894B2EF98BFB1F10
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP008230 Genomic DNA. Translation: BAE84873.1.
RefSeqiWP_011460838.1. NC_007907.1.

Genome annotation databases

EnsemblBacteriaiBAE84873; BAE84873; DSY3084.
KEGGidsy:DSY3084.
PATRICi21675044. VBIDesHaf65307_3455.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP008230 Genomic DNA. Translation: BAE84873.1.
RefSeqiWP_011460838.1. NC_007907.1.

3D structure databases

ProteinModelPortaliQ24SW9.
SMRiQ24SW9. Positions 1-277.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi138119.DSY3084.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiBAE84873; BAE84873; DSY3084.
KEGGidsy:DSY3084.
PATRICi21675044. VBIDesHaf65307_3455.

Phylogenomic databases

eggNOGiENOG4108HMW. Bacteria.
COG0752. LUCA.
HOGENOMiHOG000264291.
KOiK01878.
OMAiLGSYYQF.
OrthoDBiEOG661H9S.

Enzyme and pathway databases

BioCyciDHAF138119:GHT5-3151-MONOMER.

Family and domain databases

HAMAPiMF_00254. Gly_tRNA_synth_alpha.
InterProiIPR006194. Gly-tRNA-synth_heterodimer.
IPR002310. Gly-tRNA_ligase_asu.
[Graphical view]
PfamiPF02091. tRNA-synt_2e. 1 hit.
[Graphical view]
PRINTSiPR01044. TRNASYNTHGA.
TIGRFAMsiTIGR00388. glyQ. 1 hit.
PROSITEiPS50861. AA_TRNA_LIGASE_II_GLYAB. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Complete genome sequence of the dehalorespiring bacterium Desulfitobacterium hafniense Y51 and comparison with Dehalococcoides ethenogenes 195."
    Nonaka H., Keresztes G., Shinoda Y., Ikenaga Y., Abe M., Naito K., Inatomi K., Furukawa K., Inui M., Yukawa H.
    J. Bacteriol. 188:2262-2274(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Y51.

Entry informationi

Entry nameiSYGA_DESHY
AccessioniPrimary (citable) accession number: Q24SW9
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: April 18, 2006
Last modified: December 9, 2015
This is version 62 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Aminoacyl-tRNA synthetases
    List of aminoacyl-tRNA synthetase entries
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.