Reviewed, UniProtKB/Swiss-Prot Q24SK5 (TRPF_DESHY)

Names and origin

Protein names

Recommended name:
    N-(5'-phosphoribosyl)anthranilate isomerase
      Short name=PRAI
    EC=5.3.1.24

Gene names

Name:	trpF
Ordered Locus Names:	DSY3198

Organism

Desulfitobacterium hafniense (strain Y51) [Complete proteome] [HAMAP]

Taxonomic identifier

138119 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Clostridia › Clostridiales › Peptococcaceae › Desulfitobacterium

Protein attributes

Sequence length	237 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	N-(5-phospho-beta-D-ribosyl)anthranilate = 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate. HAMAP MF_00135
Pathway	Amino-acid biosynthesis; L-tryptophan biosynthesis; L-tryptophan from chorismate: step 3/5. HAMAP MF_00135
Sequence similarities	Belongs to the trpF family.

Ontologies

Keywords
Biological process	Amino-acid biosynthesis Aromatic amino acid biosynthesis Tryptophan biosynthesis
Molecular function	Isomerase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	tryptophan biosynthetic process Inferred from electronic annotation. Source: HAMAP
Molecular function	phosphoribosylanthranilate isomerase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 237	237	N-(5'-phosphoribosyl)anthranilate isomerase HAMAP MF_00135		PRO_1000018593

Sequences

	Sequence		Length	Mass (Da)
	Q24SK5-1 [UniParc]. Last modified April 18, 2006. Version 1. Checksum: 9682C33BDE91280E	FASTA	237	25,749
	10 20 30 40 50 60 MPRIKICGIR TGEEARWAVE AGADALGFIF VPHSKRYIQP ETAREIILNL PPLISKVGVF 70 80 90 100 110 120 AQASPEHVGR IVHECSLDTI QLHGNEDPRL YRHLSVTKIK AFSFPSAPAP GNSSEAAPDF 130 140 150 160 170 180 SLVETSPSSS LPTSFRELPP ASLHGILLDS SAGGRTGGTG IPLPWHTPVF QDFLHQVGDL 190 200 210 220 230 GYPLILAGGL NPDNILEAIR LTRPYGVDVS SGVERNGRKD REKIQHFISQ ARKESPL

References

[1]

"Complete genome sequence of the dehalorespiring bacterium Desulfitobacterium hafniense Y51 and comparison with Dehalococcoides ethenogenes 195." Nonaka H., Keresztes G., Shinoda Y., Ikenaga Y., Abe M., Naito K., Inatomi K., Furukawa K., Inui M., Yukawa H. J. Bacteriol. 188:2262-2274(2006) [PubMed: 16513756] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	AP008230 Genomic DNA. Translation: BAE84987.1.
RefSeq	YP_519431.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	3956949.
GenomeReviews	Gene locus DSY3198 in contig AP008230_GR.
KEGG	dsy:DSY3198.
NMPDR	fig|138119.3.peg.3440.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q24SK5.
OMA	Q24SK5. SKICGIT.
Enzyme and pathway databases
BioCyc	DHAF138119:DSY3198-MON.
Family and domain databases
HAMAP	MF_00135. [Tree]
InterPro	IPR013785. Aldolase_TIM. IPR001240. PRAI. [Graphical view]
Gene3D	G3DSA:3.20.20.70. Aldolase_TIM. 1 hit.
Pfam	PF00697. PRAI. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

TRPF_DESHY

Accession

Primary (citable) accession number: Q24SK5

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
Last sequence update:	April 18, 2006
Last modified:	June 16, 2009
This is version 22 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)