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Q24SG7 (MAMA_DESHY) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 58. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Methylaspartate mutase S chain

EC=5.4.99.1
Alternative name(s):
Glutamate mutase subunit sigma
Gene names
Name:mamA
Ordered Locus Names:DSY3236
OrganismDesulfitobacterium hafniense (strain Y51) [Complete proteome] [HAMAP]
Taxonomic identifier138119 [NCBI]
Taxonomic lineageBacteriaFirmicutesClostridiaClostridialesPeptococcaceaeDesulfitobacterium

Protein attributes

Sequence length136 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

L-threo-3-methylaspartate = L-glutamate. HAMAP-Rule MF_00526

Cofactor

5'-deoxy-5'-adenosyl-adeninylcobamide (pseudo-coenzyme B12) By similarity.

Pathway

Amino-acid degradation; L-glutamate degradation via mesaconate pathway; acetate and pyruvate from L-glutamate: step 1/4. HAMAP-Rule MF_00526

Subunit structure

Heterotetramer of 2 E subunits and 2 S subunits By similarity.

Sequence similarities

Contains 1 B12-binding domain.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 136136Methylaspartate mutase S chain HAMAP-Rule MF_00526
PRO_0000264142

Regions

Domain3 – 136134B12-binding

Sites

Metal binding161Cobalt (cobalamin axial ligand) By similarity

Sequences

Sequence LengthMass (Da)Tools
Q24SG7 [UniParc].

Last modified April 18, 2006. Version 1.
Checksum: 051735403943D06C

FASTA13614,748
        10         20         30         40         50         60 
MEGKTLVLGV IGADVHAVGN RILDYAFTQA GFKVINIGVL ASQEEFIRAA IETAASVIMV 

        70         80         90        100        110        120 
SSLYGHGELD CRGLREKCQE SGIGDILLYV GGNLVVGKQE FSEVEKRFLA MGFNRVYPPG 

       130 
TMPEAAIEDL RKDLEL 

« Hide

References

[1]"Complete genome sequence of the dehalorespiring bacterium Desulfitobacterium hafniense Y51 and comparison with Dehalococcoides ethenogenes 195."
Nonaka H., Keresztes G., Shinoda Y., Ikenaga Y., Abe M., Naito K., Inatomi K., Furukawa K., Inui M., Yukawa H.
J. Bacteriol. 188:2262-2274(2006) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: Y51.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AP008230 Genomic DNA. Translation: BAE85025.1.
RefSeqYP_519469.1. NC_007907.1.

3D structure databases

ProteinModelPortalQ24SG7.
SMRQ24SG7. Positions 1-136.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING138119.DSY3236.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaBAE85025; BAE85025; DSY3236.
GeneID3957045.
KEGGdsy:DSY3236.
PATRIC21675368. VBIDesHaf65307_3612.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG2185.
HOGENOMHOG000011065.
KOK01846.
OMAHAVGNKI.
OrthoDBEOG6CP428.
ProtClustDBPRK02261.

Enzyme and pathway databases

BioCycDHAF138119:GHT5-3308-MONOMER.
UniPathwayUPA00561; UER00617.

Family and domain databases

Gene3D3.40.50.280. 1 hit.
HAMAPMF_00526. MthylAspMutase_S.
InterProIPR006159. Acid_CoA_mut_C.
IPR006158. Cobalamin-bd.
IPR006394. Me_Asp_mutase.
[Graphical view]
PfamPF02310. B12-binding. 1 hit.
[Graphical view]
SUPFAMSSF52242. SSF52242. 1 hit.
TIGRFAMsTIGR00640. acid_CoA_mut_C. 1 hit.
TIGR01501. MthylAspMutase. 1 hit.
PROSITEPS51332. B12_BINDING. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameMAMA_DESHY
AccessionPrimary (citable) accession number: Q24SG7
Entry history
Integrated into UniProtKB/Swiss-Prot: December 12, 2006
Last sequence update: April 18, 2006
Last modified: February 19, 2014
This is version 58 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways