Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Allantoinase

Gene

allB

Organism
Desulfitobacterium hafniense (strain Y51)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalyzes the conversion of allantoin (5-ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring.UniRule annotation

Catalytic activityi

(S)-allantoin + H2O = allantoate.UniRule annotation

Cofactori

Zn2+UniRule annotationNote: Binds 2 Zn2+ ions per subunit.UniRule annotation

Pathwayi: (S)-allantoin degradation

This protein is involved in step 1 of the subpathway that synthesizes allantoate from (S)-allantoin.UniRule annotation
Proteins known to be involved in this subpathway in this organism are:
  1. Allantoinase (allB)
This subpathway is part of the pathway (S)-allantoin degradation, which is itself part of Nitrogen metabolism.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes allantoate from (S)-allantoin, the pathway (S)-allantoin degradation and in Nitrogen metabolism.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi61Zinc 1UniRule annotation1
Metal bindingi63Zinc 1UniRule annotation1
Metal bindingi148Zinc 1; via carbamate groupUniRule annotation1
Metal bindingi148Zinc 2; via carbamate groupUniRule annotation1
Metal bindingi184Zinc 2UniRule annotation1
Metal bindingi240Zinc 2UniRule annotation1
Metal bindingi313Zinc 1UniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHydrolase
Biological processPurine metabolism
LigandMetal-binding, Zinc

Enzyme and pathway databases

BioCyciDHAF138119:G1G2E-4518-MONOMER
UniPathwayiUPA00395; UER00653

Names & Taxonomyi

Protein namesi
Recommended name:
AllantoinaseUniRule annotation (EC:3.5.2.5UniRule annotation)
Alternative name(s):
Allantoin-utilizing enzymeUniRule annotation
Gene namesi
Name:allBUniRule annotation
Ordered Locus Names:DSY4164
OrganismiDesulfitobacterium hafniense (strain Y51)
Taxonomic identifieri138119 [NCBI]
Taxonomic lineageiBacteriaFirmicutesClostridiaClostridialesPeptococcaceaeDesulfitobacterium
Proteomesi
  • UP000001946 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003176731 – 449AllantoinaseAdd BLAST449

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei148N6-carboxylysineUniRule annotation1

Post-translational modificationi

Carbamylation allows a single lysine to coordinate two zinc ions.UniRule annotation

Proteomic databases

PRIDEiQ24PT9

Interactioni

Subunit structurei

Homotetramer.UniRule annotation

Protein-protein interaction databases

STRINGi138119.DSY4164

Structurei

3D structure databases

ProteinModelPortaliQ24PT9
SMRiQ24PT9
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the metallo-dependent hydrolases superfamily. Allantoinase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4107RNN Bacteria
COG0044 LUCA
HOGENOMiHOG000219146
KOiK01466
OMAiHFNEPGR
OrthoDBiPOG091H02CH

Family and domain databases

Gene3Di2.30.40.10, 3 hits
HAMAPiMF_01645 Hydantoinase, 1 hit
InterProiView protein in InterPro
IPR017593 Allantoinase
IPR006680 Amidohydro-rel
IPR011059 Metal-dep_hydrolase_composite
IPR032466 Metal_Hydrolase
PfamiView protein in Pfam
PF01979 Amidohydro_1, 1 hit
SUPFAMiSSF51338 SSF51338, 2 hits
SSF51556 SSF51556, 1 hit
TIGRFAMsiTIGR03178 allantoinase, 1 hit

Sequencei

Sequence statusi: Complete.

Q24PT9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSHYDLILRN GNVVCPDGVR KADIAVSDGK IVLIAEEIPG DAKEVIDAAG
60 70 80 90 100
KHVFPGITDG HVHFNDPGRT EWETISTGSS ALAAGGGVAY FDMPLNCSPC
110 120 130 140 150
TLDAVNFNNK LAVAQKDSLV DYGFWGGLTS ANLDKLDELA ECGVIGFKAF
160 170 180 190 200
ACHSGIDEFP RMDDYTALVG MEKLAKLGLP LMVHCENAEI TKELTELSLA
210 220 230 240 250
NNRTGVRDYF AARPPITEIE NVSRMITFAE ETGCKLIIAH ISTAKAVDLV
260 270 280 290 300
AQARARGVDV YCETIGHYLY LTGDDVERLG TVAKCSPPIR DGENQLQMWG
310 320 330 340 350
RLFNDNIAFV SSDHSPCDPK LKNGEFMRVW GGISACQTTL QGLLTHAYHD
360 370 380 390 400
RKFPLVKIAQ LTAQHVNEIF KIKGKGQINL GYDADFALVD LNHEFTLQAE
410 420 430 440
DLFYKHKVSP YVGDRFRGSV SQTILRGTTI YKDGKIVSQP IGKHLRPHQ
Length:449
Mass (Da):49,228
Last modified:April 18, 2006 - v1
Checksum:iE96C55461047E725
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP008230 Genomic DNA Translation: BAE85953.1
RefSeqiWP_011461639.1, NC_007907.1

Genome annotation databases

EnsemblBacteriaiBAE85953; BAE85953; DSY4164
KEGGidsy:DSY4164

Similar proteinsi

Entry informationi

Entry nameiALLB_DESHY
AccessioniPrimary (citable) accession number: Q24PT9
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 5, 2008
Last sequence update: April 18, 2006
Last modified: May 23, 2018
This is version 75 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

Cookie policy

We would like to use anonymized google analytics cookies to gather statistics on how uniprot.org is used in aggregate. Learn more

UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health