Unreviewed,
UniProtKB/TrEMBL Q24M88 (Q24M88_HUMAN)
Last modified
December 15, 2009.
Version 32.
History...
Clusters with 100%,
90%,
50% identity |
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Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information
Names and origin
| Protein names | Submitted name: Phosphoinositide-3-kinase gamma polypeptide EMBL AAS75801.1 |
| Organism | Homo sapiens (Human) EMBL AAS75801.1 |
| Taxonomic identifier | 9606 [NCBI] |
| Taxonomic lineage | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Protein attributes
| Sequence length | 104 AA. |
| Sequence status | Fragment. |
| Protein existence | Evidence at transcript level. |
Ontologies
| Keywords | |
|---|---|
| Molecular function | Kinase Spearmint SPM000403 EMBL AAS75801.1 Transferase |
| Gene Ontology (GO) | |
| Biological process | negative regulation of apoptosis Inferred from electronic annotation. Source: Compara phosphoinositide phosphorylationInferred from electronic annotation. Source: InterPro phosphoinositide-mediated signalingInferred from electronic annotation. Source: InterPro protein amino acid phosphorylationInferred from electronic annotation. Source: Compara |
| Molecular function | inositol or phosphatidylinositol kinase activity Inferred from electronic annotation. Source: InterPro phosphotransferase activity, alcohol group as acceptorInferred from electronic annotation. Source: InterPro |
| Complete GO annotation... | |
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | |||
Experimental info | ||||||||
|---|---|---|---|---|---|---|---|---|
| Non-terminal residue | 1 | 1 | EMBL AAS75801.1 | |||||
| Non-terminal residue | 104 | 1 | EMBL AAS75801.1 | |||||
Sequences
References
| [1] | "Phosphatidylinositol 3-kinase gamma signaling through protein kinase Czeta induces NADPH oxidase-mediated oxidant generation and NF-kappaB activation in endothelial cells." Frey R.S., Gao X., Javaid K., Siddiqui S.S., Rahman A., Malik A.B. J. Biol. Chem. 281:16128-16138(2006) [PubMed: 16527821] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. |
| + | Additional computationally mapped references. |
Cross-references
Sequence databases | |
|---|---|
| EMBL GenBank DDBJ | AY496423 mRNA. Translation: AAS75801.1. |
| IPI | IPI00946767. |
| UniGene | Hs.32942 |
3D structure databases | |
| SMR | Q24M88. Positions 1-104. |
| ModBase | Search... |
Protein-protein interaction databases | |
| STRING | Q24M88. |
Genome annotation databases | |
| Ensembl | ENST00000359195; ENSP00000352121; ENSG00000105851; Homo sapiens. [Genome view] ENST00000440650; ENSP00000392258; ENSG00000105851; Homo sapiens. [Genome view] ENST00000473541; ENSP00000417623; ENSG00000105851; Homo sapiens. [Genome view] ENST00000496166; ENSP00000419260; ENSG00000105851; Homo sapiens. [Genome view] |
Organism-specific databases | |
| HGNC | HGNC:8978. PIK3CG. |
Phylogenomic databases | |
| HOVERGEN | Q24M88. |
Gene expression databases | |
| ArrayExpress | Q24M88. |
| Bgee | Q24M88. |
Family and domain databases | |
| InterPro | IPR011009. Kinase-like_dom. IPR000403. PI3/4_kinase_cat. IPR018936. PI3/4_kinase_CS. IPR015433. PI_Kinase. [Graphical view] |
| PANTHER | PTHR10048. PI_Kinase. 1 hit. |
| Pfam | PF00454. PI3_PI4_kinase. 1 hit. [Graphical view] |
| PROSITE | PS00915. PI3_4_KINASE_1. 1 hit. PS50290. PI3_4_KINASE_3. 1 hit. [Graphical view] |
| ProtoNet | Search... |
Entry information
| Entry name | Q24M88_HUMAN | ||||||||
| Accession | Primary (citable) accession number: Q24M88 | ||||||||
| Entry history |
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| Entry status | Unreviewed (UniProtKB/TrEMBL) | ||||||||
| Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. | ||||||||

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