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Protein

Leucine-rich repeat-containing protein 10

Gene

LRRC10

Organism
Bos taurus (Bovine)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

May play important roles in cardiac development and/or cardiac function.By similarity

GO - Biological processi

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Recommended name:
Leucine-rich repeat-containing protein 10
Gene namesi
Name:LRRC10
OrganismiBos taurus (Bovine)
Taxonomic identifieri9913 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaRuminantiaPecoraBovidaeBovinaeBos
Proteomesi
  • UP000009136 Componenti: Chromosome 5

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 278278Leucine-rich repeat-containing protein 10PRO_0000346161Add
BLAST

Proteomic databases

PaxDbiQ24K06.

Interactioni

Protein-protein interaction databases

STRINGi9913.ENSBTAP00000025497.

Structurei

3D structure databases

ProteinModelPortaliQ24K06.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Repeati30 – 5122LRR 1Add
BLAST
Repeati52 – 7423LRR 2Add
BLAST
Repeati76 – 9722LRR 3Add
BLAST
Repeati98 – 12124LRR 4Add
BLAST
Repeati123 – 14321LRR 5Add
BLAST
Repeati144 – 16623LRR 6Add
BLAST
Repeati167 – 18923LRR 7Add
BLAST
Repeati191 – 21323LRR 8Add
BLAST

Sequence similaritiesi

Contains 8 LRR (leucine-rich) repeats.Curated

Keywords - Domaini

Leucine-rich repeat, Repeat

Phylogenomic databases

eggNOGiKOG0619. Eukaryota.
COG4886. LUCA.
GeneTreeiENSGT00840000129676.
HOGENOMiHOG000113359.
HOVERGENiHBG055066.
InParanoidiQ24K06.
OMAiIDVDRNS.
OrthoDBiEOG7TF79V.
TreeFamiTF332853.

Family and domain databases

Gene3Di3.80.10.10. 1 hit.
InterProiIPR032675. L_dom-like.
IPR001611. Leu-rich_rpt.
IPR003591. Leu-rich_rpt_typical-subtyp.
[Graphical view]
PfamiPF13855. LRR_8. 1 hit.
[Graphical view]
SMARTiSM00369. LRR_TYP. 5 hits.
[Graphical view]
SUPFAMiSSF52058. SSF52058. 1 hit.
PROSITEiPS51450. LRR. 7 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q24K06-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGNTIRAFVA FIPADRCQNY VARDLREMPL DRMVDLSGSQ LRRFPVHVCS
60 70 80 90 100
FQELVKLYLS DNRLNSLPPE LGQLQNLQIL ALDFNNFKAL PQVVCTLKQL
110 120 130 140 150
CILYLGNNKL CDLPRELSLL QNLRTLWVEA NYLTKLPEVV CELSLLKTLH
160 170 180 190 200
AGSNALRLLP GQLQRLRELR TIWLSGNLLT DFPPVLLHMP FLEIIDVDRN
210 220 230 240 250
SIRYFPSLAH LSSLKLVIYD HNPCRNAPKV AKGVRRVGRW AEETPEPDPR
260 270
KARRYALARE ESQEAQLPAL PPLPPTNS
Length:278
Mass (Da):31,760
Last modified:April 18, 2006 - v1
Checksum:i8D7EF12600078D51
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC114091 mRNA. Translation: AAI14092.1.
RefSeqiNP_001069225.1. NM_001075757.2.
UniGeneiBt.56793.

Genome annotation databases

EnsembliENSBTAT00000025497; ENSBTAP00000025497; ENSBTAG00000019157.
GeneIDi517750.
KEGGibta:517750.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC114091 mRNA. Translation: AAI14092.1.
RefSeqiNP_001069225.1. NM_001075757.2.
UniGeneiBt.56793.

3D structure databases

ProteinModelPortaliQ24K06.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9913.ENSBTAP00000025497.

Proteomic databases

PaxDbiQ24K06.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSBTAT00000025497; ENSBTAP00000025497; ENSBTAG00000019157.
GeneIDi517750.
KEGGibta:517750.

Organism-specific databases

CTDi376132.

Phylogenomic databases

eggNOGiKOG0619. Eukaryota.
COG4886. LUCA.
GeneTreeiENSGT00840000129676.
HOGENOMiHOG000113359.
HOVERGENiHBG055066.
InParanoidiQ24K06.
OMAiIDVDRNS.
OrthoDBiEOG7TF79V.
TreeFamiTF332853.

Family and domain databases

Gene3Di3.80.10.10. 1 hit.
InterProiIPR032675. L_dom-like.
IPR001611. Leu-rich_rpt.
IPR003591. Leu-rich_rpt_typical-subtyp.
[Graphical view]
PfamiPF13855. LRR_8. 1 hit.
[Graphical view]
SMARTiSM00369. LRR_TYP. 5 hits.
[Graphical view]
SUPFAMiSSF52058. SSF52058. 1 hit.
PROSITEiPS51450. LRR. 7 hits.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. NIH - Mammalian Gene Collection (MGC) project
    Submitted (FEB-2006) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: Hereford.
    Tissue: Heart ventricle.

Entry informationi

Entry nameiLRC10_BOVIN
AccessioniPrimary (citable) accession number: Q24K06
Entry historyi
Integrated into UniProtKB/Swiss-Prot: September 2, 2008
Last sequence update: April 18, 2006
Last modified: June 8, 2016
This is version 73 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.