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Q24JJ8 (GLO3_ARATH) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 61. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Peroxisomal (S)-2-hydroxy-acid oxidase GLO3

EC=1.1.3.15
Alternative name(s):
Glycolate oxidase 3
Short name=AtGLO3
Short name=GOX 3
Short chain alpha-hydroxy acid oxidase GLO3
Gene names
Name:GLO3
Ordered Locus Names:At3g14150
ORF Names:MAG2.11
OrganismArabidopsis thaliana (Mouse-ear cress) [Reference proteome]
Taxonomic identifier3702 [NCBI]
Taxonomic lineageEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis

Protein attributes

Sequence length363 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Catalytic activity

(S)-2-hydroxy acid + O2 = 2-oxo acid + H2O2.

Cofactor

FMN By similarity.

Pathway

Photosynthesis; photorespiration; glycine from 2-phosphoglycolate: step 2/3.

Subunit structure

Homotetramer or homooctamer By similarity.

Subcellular location

Peroxisome By similarity.

Sequence similarities

Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

Contains 1 FMN hydroxy acid dehydrogenase domain.

Sequence caution

The sequence BAB02979.1 differs from that shown. Reason: Erroneous gene model prediction.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 363363Peroxisomal (S)-2-hydroxy-acid oxidase GLO3
PRO_0000403406

Regions

Domain1 – 357357FMN hydroxy acid dehydrogenase
Nucleotide binding283 – 30725FMN By similarity
Motif361 – 3633Microbody targeting signal Potential

Sites

Active site2521Proton acceptor By similarity
Binding site1071FMN By similarity
Binding site1281FMN By similarity
Binding site1301Substrate By similarity
Binding site1561FMN By similarity
Binding site1651Substrate By similarity
Binding site2281FMN By similarity
Binding site2551Substrate Potential

Experimental info

Sequence conflict871P → L in AAM67194. Ref.4
Sequence conflict3091I → M in AAM67194. Ref.4

Sequences

Sequence LengthMass (Da)Tools
Q24JJ8 [UniParc].

Last modified April 18, 2006. Version 1.
Checksum: 8AA94B1A354BA60C

FASTA36340,130
        10         20         30         40         50         60 
MDQIVNVDEF QELAKQALPK MYYDFYNGGA EDQHTLNENV QAFRRIMFRP RVLVDVSKID 

        70         80         90        100        110        120 
MSTKILGYPI SAPIMIAPTG NHKLAHPEGE TATAKAAAAC NTIMIVSYMS SCTFEEIASS 

       130        140        150        160        170        180 
CNAVRFLQIY VYKRRDITAQ VVKRAEKAGF KAIVLTVDVP RLGRREADIK NKMISPQLKN 

       190        200        210        220        230        240 
FEGLFSTEVR PSKGSGVQAF ASRAFDASFS WKDIEWLRSI TELPILVKGI LTREDALKAV 

       250        260        270        280        290        300 
EAGVDGIIVS NHGGRQLDYS PATITVLEEV VQVVRGRIPV LLDGGVRRGT DVFKALALGA 

       310        320        330        340        350        360 
QAVLIGRPII YGLAAKGEDG VKKVIDMLKN EFEITMALSG CPTIDDITRN HVRTENERLH 


SML 

« Hide

References

« Hide 'large scale' references
[1]"Structural analysis of Arabidopsis thaliana chromosome 3. II. Sequence features of the 4,251,695 bp regions covered by 90 P1, TAC and BAC clones."
Kaneko T., Katoh T., Sato S., Nakamura Y., Asamizu E., Tabata S.
DNA Res. 7:217-221(2000) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: cv. Columbia.
[2]The Arabidopsis Information Resource (TAIR)
Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases
Cited for: GENOME REANNOTATION.
Strain: cv. Columbia.
[3]"Arabidopsis ORF clones."
Shinn P., Chen H., Kim C.J., Ecker J.R.
Submitted (JUN-2008) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Strain: cv. Columbia.
[4]"Full-length cDNA from Arabidopsis thaliana."
Brover V.V., Troukhan M.E., Alexandrov N.A., Lu Y.-P., Flavell R.B., Feldmann K.A.
Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
[5]"Inducible antisense suppression of glycolate oxidase reveals its strong regulation over photosynthesis in rice."
Xu H.-W., Zhang J., Zeng J., Jiang L., Liu E., Peng C., He Z.-H., Peng X.-X.
J. Exp. Bot. 60:1799-1809(2009) [PubMed] [Europe PMC] [Abstract]
Cited for: GENE FAMILY, NOMENCLATURE.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AP000600 Genomic DNA. Translation: BAB02979.1. Sequence problems.
CP002686 Genomic DNA. Translation: AEE75477.1.
CP002686 Genomic DNA. Translation: AEE75478.1.
BT024891 mRNA. Translation: ABD85162.1.
AY088888 mRNA. Translation: AAM67194.1.
RefSeqNP_001078152.1. NM_001084683.1.
NP_188031.1. NM_112271.3.
UniGeneAt.39282.

3D structure databases

ProteinModelPortalQ24JJ8.
SMRQ24JJ8. Positions 3-355.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING3702.AT3G14150.1-P.

Proteomic databases

PaxDbQ24JJ8.
PRIDEQ24JJ8.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsAT3G14150.1; AT3G14150.1; AT3G14150.
AT3G14150.2; AT3G14150.2; AT3G14150.
GeneID820632.
KEGGath:AT3G14150.

Organism-specific databases

TAIRAT3G14150.

Phylogenomic databases

eggNOGCOG1304.
HOGENOMHOG000217463.
InParanoidQ24JJ8.
KOK11517.
OMAYVQHAEA.
PhylomeDBQ24JJ8.

Enzyme and pathway databases

BioCycARA:AT3G14150-MONOMER.
ARA:GQT-2460-MONOMER.
UniPathwayUPA00951; UER00912.

Gene expression databases

GenevestigatorQ24JJ8.

Family and domain databases

Gene3D3.20.20.70. 1 hit.
InterProIPR013785. Aldolase_TIM.
IPR012133. Alpha-hydoxy_acid_DH_FMN.
IPR000262. FMN-dep_DH.
IPR008259. FMN_hydac_DH_AS.
[Graphical view]
PfamPF01070. FMN_dh. 1 hit.
[Graphical view]
PIRSFPIRSF000138. Al-hdrx_acd_dh. 1 hit.
PROSITEPS00557. FMN_HYDROXY_ACID_DH_1. 1 hit.
PS51349. FMN_HYDROXY_ACID_DH_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

PROQ24JJ8.

Entry information

Entry nameGLO3_ARATH
AccessionPrimary (citable) accession number: Q24JJ8
Secondary accession number(s): Q8L8P3, Q9LJH3
Entry history
Integrated into UniProtKB/Swiss-Prot: January 11, 2011
Last sequence update: April 18, 2006
Last modified: May 14, 2014
This is version 61 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways

Arabidopsis thaliana

Arabidopsis thaliana: entries and gene names