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Protein
Submitted name:

Cathepsin

Gene
N/A
Organism
Fasciola hepatica (Liver fluke)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

Keywordsi

Molecular functionHydrolase, Protease, Thiol proteaseSAAS annotation

Protein family/group databases

MEROPSiC01.142.

Names & Taxonomyi

Protein namesi
Submitted name:
CathepsinImported
OrganismiFasciola hepatica (Liver fluke)Imported
Taxonomic identifieri6192 [NCBI]
Taxonomic lineageiEukaryotaMetazoaPlatyhelminthesTrematodaDigeneaPlagiorchiidaEchinostomataEchinostomatoideaFasciolidaeFasciola

Structurei

3D structure databases

ProteinModelPortaliQ24941.
SMRiQ24941.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini21 – 80Inhibitor_I29InterPro annotationAdd BLAST60
Domaini108 – 321Pept_C1InterPro annotationAdd BLAST214

Sequence similaritiesi

Belongs to the peptidase C1 family.UniRule annotationSAAS annotation

Family and domain databases

InterProiView protein in InterPro
IPR025661. Pept_asp_AS.
IPR000169. Pept_cys_AS.
IPR025660. Pept_his_AS.
IPR013128. Peptidase_C1A.
IPR000668. Peptidase_C1A_C.
IPR013201. Prot_inhib_I29.
PANTHERiPTHR12411. PTHR12411. 1 hit.
PfamiView protein in Pfam
PF08246. Inhibitor_I29. 1 hit.
PF00112. Peptidase_C1. 1 hit.
PRINTSiPR00705. PAPAIN.
SMARTiView protein in SMART
SM00848. Inhibitor_I29. 1 hit.
SM00645. Pept_C1. 1 hit.
PROSITEiView protein in PROSITE
PS00640. THIOL_PROTEASE_ASN. 1 hit.
PS00139. THIOL_PROTEASE_CYS. 1 hit.
PS00639. THIOL_PROTEASE_HIS. 1 hit.

Sequencei

Sequence statusi: Complete.

Q24941-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRLVILTLLI VGVFASNDDL WHQWKRIYNK EYKGADDDHR RNIWEQNVKH
60 70 80 90 100
IQEHNLRHDL GLVTYKLGLN QFTDMTFEEF KAKYLTEMPR ASELLSHGIP
110 120 130 140 150
YKANKRAVPD RIDWRESGYV TEVKDQGGCG SCWAFSTTGA MEGQYMKNEK
160 170 180 190 200
TSISFSEQQL VDCSGPFGNY GCNGGLMENA YEYLKRFGLE TESSYPYRAV
210 220 230 240 250
EGQCRYNEQL GVAKVTGYYT VHSGDEVELQ NLVGCRRPAA VALDVESDFM
260 270 280 290 300
MYRSGIYQSQ TCSPDRLNHG VLAVGYGIQD GTDYWIVKNS WGTWWGEDGY
310 320
IRMVRKRGNM CGIASLASVP MVAQFP
Length:326
Mass (Da):37,177
Last modified:November 1, 1996 - v1
Checksum:i6CCEB77A10798081
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L33772 mRNA. Translation: AAA29137.1.

Similar proteinsi

Entry informationi

Entry nameiQ24941_FASHE
AccessioniPrimary (citable) accession number: Q24941
Entry historyiIntegrated into UniProtKB/TrEMBL: November 1, 1996
Last sequence update: November 1, 1996
Last modified: August 30, 2017
This is version 72 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)