Q24640 (ADHR_DROSU) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Alcohol dehydrogenase-related 31 kDa protein

Gene names

Name:	Adhr
Synonyms:	Adh-dup

Organism

Drosophila subobscura (Fruit fly)

Taxonomic identifier

7241 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Arthropoda › Hexapoda › Insecta › Pterygota › Neoptera › Endopterygota › Diptera › Brachycera › Muscomorpha › Ephydroidea › Drosophilidae › Drosophila › Sophophora

Protein attributes

Sequence length	279 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Sequence similarities

Belongs to the short-chain dehydrogenases/reductases (SDR) family.

Ontologies

Keywords
Molecular function	Oxidoreductase
Gene Ontology (GO)
Molecular function	alcohol dehydrogenase (NAD) activity Inferred from electronic annotation. Source: InterPro nucleotide binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 279	279	Alcohol dehydrogenase-related 31 kDa protein		PRO_0000054512
Regions
	Nucleotide binding	11 – 34	24	NAD or NADP By similarity
Sites
	Active site	152	1	Proton acceptor By similarity
	Binding site	139	1	Substrate By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q24640 [UniParc]. Last modified November 1, 1996. Version 1. Checksum: 7033F23D6F5F04F6	FASTA	279	31,078
	10 20 30 40 50 60 MYDLTGKHVC YVADCGGIAL ETSKVLMTKN IAKLAILQSV ENQPAIARLQ SIKHSTQIFF 70 80 90 100 110 120 WTFDVTMARQ EMKKYFDEVM VQMDYIDVLI NGATLCDERN IDATINTNLT GMMNTVATVL 130 140 150 160 170 180 PYMDRKMGGS GGLIVNVTSV IGLDPSPVFC AYSASKFGVI GFTRSLADPL YYTQNGVAVM 190 200 210 220 230 240 AVCCGPTKVF VDRELNAFLE YGQTFADRLR RAPCQSTAVC GQNIVTAIER SENGQIWIAD 250 260 270 KGGLELLTLH WYWHMADQFL SYMQSTDDEN QEQFVSGQR

References

[1]	"The Drosophila subobscura Adh genomic region contains valuable evolutionary markers." Marfany G., Gonzalez-Duarte R. Mol. Biol. Evol. 9:261-277(1992) [PubMed: 1560762] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	M55545 Genomic DNA. Translation: AAA28340.1.
PIR	B42180.
3D structure databases
ProteinModelPortal	Q24640.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Organism-specific databases
FlyBase	FBgn0012931. Dsub\Adhr.
Family and domain databases
InterPro	IPR002427. ADH-rel. IPR002424. ADH_insect. IPR002198. DH_sc/Rdtase_SDR. IPR016040. NAD(P)-bd_dom. IPR020904. Sc_DH/Rdtase_CS. [Graphical view]
Gene3D	G3DSA:3.40.50.720. NAD(P)-bd. 1 hit.
Pfam	PF00106. adh_short. 1 hit. [Graphical view]
PRINTS	PR01170. ADHRELATED. PR01167. INSADHFAMILY. PR00080. SDRFAMILY.
PROSITE	PS00061. ADH_SHORT. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

ADHR_DROSU

Accession

Primary (citable) accession number: Q24640

Entry history

Integrated into UniProtKB/Swiss-Prot:	July 15, 1998
Last sequence update:	November 1, 1996
Last modified:	December 14, 2011
This is version 53 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Drosophila annotation project