Q24536 (SSL_DROME) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Suppressor-of-stellate-like protein
Short name=Su(ste)-like
Short name=Suste-like protein

Gene names

Name:	Ssl
ORF Names:	CG13591

Organism

Drosophila melanogaster (Fruit fly)

Taxonomic identifier

7227 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Arthropoda › Hexapoda › Insecta › Pterygota › Neoptera › Endopterygota › Diptera › Brachycera › Muscomorpha › Ephydroidea › Drosophilidae › Drosophila › Sophophora

Protein attributes

Sequence length	219 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Sequence similarities

Belongs to the casein kinase 2 subunit beta family.

Ontologies

Keywords
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Cellular component	protein kinase CK2 complex Inferred from electronic annotation. Source: InterPro
Molecular function	protein kinase activity Non-traceable author statement. Source: FlyBase protein kinase regulator activity Inferred from direct assay. Source: FlyBase
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 219	219	Suppressor-of-stellate-like protein		PRO_0000068269
Experimental info
	Sequence conflict	143	1	N → I in AAB65818. Ref.1

Sequences

	Sequence		Length	Mass (Da)
	Q24536 [UniParc]. Last modified November 1, 1996. Version 1. Checksum: 3F2494C8D1278CC3	FASTA	219	25,191
	10 20 30 40 50 60 MSCPRSIEIP DGSWIDWFLG IKGHEFSCRV PNEYIQDKFN LTGLEFDSQT LEVVLDPEFD 70 80 90 100 110 120 NEDWDCAEEK KLYGMIHARY IVSPRGIEDM RLKYERGDFG SCPRVFCKRQ KVLPVGLHDV 130 140 150 160 170 180 WDKAQVKIYC PSCNNVYIPL PHNGMLDGAM FGTSFPHMFF MQLPSLIPSP PVEKYIPRIY 190 200 210 GFQLHKKALM PPESAESPPI KVESSVSKSP SWLRNVPNF

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Acquisition and amplification of a testis-expressed autosomal gene, SSL, by the Drosophila Y chromosome." Kalmykova A.I., Shevelyov Y.Y., Dobritsa A.A., Gvozdev V.A. Proc. Natl. Acad. Sci. U.S.A. 94:6297-6302(1997) [PubMed: 9177211] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA]. Strain: Batumi and Canton-S.
[2]	"The genome sequence of Drosophila melanogaster." Adams M.D., Celniker S.E., Holt R.A., Evans C.A., Gocayne J.D., Amanatides P.G., Scherer S.E., Li P.W., Hoskins R.A., Galle R.F., George R.A., Lewis S.E., Richards S., Ashburner M., Henderson S.N., Sutton G.G., Wortman J.R., Yandell M.D. , Zhang Q., Chen L.X., Brandon R.C., Rogers Y.-H.C., Blazej R.G., Champe M., Pfeiffer B.D., Wan K.H., Doyle C., Baxter E.G., Helt G., Nelson C.R., Miklos G.L.G., Abril J.F., Agbayani A., An H.-J., Andrews-Pfannkoch C., Baldwin D., Ballew R.M., Basu A., Baxendale J., Bayraktaroglu L., Beasley E.M., Beeson K.Y., Benos P.V., Berman B.P., Bhandari D., Bolshakov S., Borkova D., Botchan M.R., Bouck J., Brokstein P., Brottier P., Burtis K.C., Busam D.A., Butler H., Cadieu E., Center A., Chandra I., Cherry J.M., Cawley S., Dahlke C., Davenport L.B., Davies P., de Pablos B., Delcher A., Deng Z., Mays A.D., Dew I., Dietz S.M., Dodson K., Doup L.E., Downes M., Dugan-Rocha S., Dunkov B.C., Dunn P., Durbin K.J., Evangelista C.C., Ferraz C., Ferriera S., Fleischmann W., Fosler C., Gabrielian A.E., Garg N.S., Gelbart W.M., Glasser K., Glodek A., Gong F., Gorrell J.H., Gu Z., Guan P., Harris M., Harris N.L., Harvey D.A., Heiman T.J., Hernandez J.R., Houck J., Hostin D., Houston K.A., Howland T.J., Wei M.-H., Ibegwam C., Jalali M., Kalush F., Karpen G.H., Ke Z., Kennison J.A., Ketchum K.A., Kimmel B.E., Kodira C.D., Kraft C.L., Kravitz S., Kulp D., Lai Z., Lasko P., Lei Y., Levitsky A.A., Li J.H., Li Z., Liang Y., Lin X., Liu X., Mattei B., McIntosh T.C., McLeod M.P., McPherson D., Merkulov G., Milshina N.V., Mobarry C., Morris J., Moshrefi A., Mount S.M., Moy M., Murphy B., Murphy L., Muzny D.M., Nelson D.L., Nelson D.R., Nelson K.A., Nixon K., Nusskern D.R., Pacleb J.M., Palazzolo M., Pittman G.S., Pan S., Pollard J., Puri V., Reese M.G., Reinert K., Remington K., Saunders R.D.C., Scheeler F., Shen H., Shue B.C., Siden-Kiamos I., Simpson M., Skupski M.P., Smith T.J., Spier E., Spradling A.C., Stapleton M., Strong R., Sun E., Svirskas R., Tector C., Turner R., Venter E., Wang A.H., Wang X., Wang Z.-Y., Wassarman D.A., Weinstock G.M., Weissenbach J., Williams S.M., Woodage T., Worley K.C., Wu D., Yang S., Yao Q.A., Ye J., Yeh R.-F., Zaveri J.S., Zhan M., Zhang G., Zhao Q., Zheng L., Zheng X.H., Zhong F.N., Zhong W., Zhou X., Zhu S.C., Zhu X., Smith H.O., Gibbs R.A., Myers E.W., Rubin G.M., Venter J.C. Science 287:2185-2195(2000) [PubMed: 10731132] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Berkeley.
[3]	"Annotation of the Drosophila melanogaster euchromatic genome: a systematic review." Misra S., Crosby M.A., Mungall C.J., Matthews B.B., Campbell K.S., Hradecky P., Huang Y., Kaminker J.S., Millburn G.H., Prochnik S.E., Smith C.D., Tupy J.L., Whitfield E.J., Bayraktaroglu L., Berman B.P., Bettencourt B.R., Celniker S.E., de Grey A.D.N.J. , Drysdale R.A., Harris N.L., Richter J., Russo S., Schroeder A.J., Shu S.Q., Stapleton M., Yamada C., Ashburner M., Gelbart W.M., Rubin G.M., Lewis S.E. Genome Biol. 3:RESEARCH0083.1-RESEARCH0083.22(2002) [PubMed: 12537572] [Abstract] Cited for: GENOME REANNOTATION. Strain: Berkeley.
[4]	"A Drosophila full-length cDNA resource." Stapleton M., Carlson J.W., Brokstein P., Yu C., Champe M., George R.A., Guarin H., Kronmiller B., Pacleb J.M., Park S., Wan K.H., Rubin G.M., Celniker S.E. Genome Biol. 3:RESEARCH0080.1-RESEARCH0080.8(2002) [PubMed: 12537569] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Strain: Berkeley. Tissue: Testis.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	L49382 Genomic DNA. Translation: AAB65817.1. L42285 mRNA. Translation: AAB65818.1. AE013599 Genomic DNA. Translation: AAF47214.1. AE013599 Genomic DNA. Translation: AAS64769.1. AY089437 mRNA. Translation: AAL90175.1.
RefSeq	NP_523848.2. NM_079124.2.
UniGene	Dm.2566.
3D structure databases
ProteinModelPortal	Q24536.
SMR	Q24536. Positions 7-190.
ModBase	Search...
Protein-protein interaction databases
STRING	Q24536.
Proteomic databases
PRIDE	Q24536.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblMetazoa	FBtr0072351; FBpp0072258; FBgn0015300.
GeneID	37909.
KEGG	dme:Dmel_CG13591.
Organism-specific databases
CTD	37909.
FlyBase	FBgn0015300. Ssl.
Phylogenomic databases
eggNOG	meNOG05154.
GeneTree	EMGT00050000000155.
InParanoid	Q24536.
OMA	FGSSFPH.
OrthoDB	EOG4XSJ5V.
PhylomeDB	Q24536.
Gene expression databases
Bgee	Q24536.
GermOnline	CG13591. Drosophila melanogaster.
Family and domain databases
InterPro	IPR016149. Casein_kin_II_reg-sub_a-hlx. IPR016150. Casein_kin_II_reg-sub_b-sht. IPR000704. Casein_kinase_II_reg-sub. [Graphical view]
Gene3D	G3DSA:1.10.1820.10. Casein_kin_II_reg-sub_a-hlx. 1 hit. G3DSA:2.20.25.20. Casein_kin_II_reg-sub_b-sht. 1 hit.
KO	K03115.
PANTHER	PTHR11740. CAS_kinase_II. 1 hit.
Pfam	PF01214. CK_II_beta. 1 hit. [Graphical view]
PRINTS	PR00472. CASNKINASEII.
SMART	SM01085. CK_II_beta. 1 hit. [Graphical view]
SUPFAM	SSF57798. Casein_kinase_II_reg-sub. 1 hit.
PROSITE	PS01101. CK2_BETA. 1 hit. [Graphical view]
ProtoNet	Search...
Other
NextBio	805991.

Entry information

Entry name

SSL_DROME

Accession

Primary (citable) accession number: Q24536
Secondary accession number(s): A4UZV0, Q24540, Q9W163

Entry history

Integrated into UniProtKB/Swiss-Prot:	July 15, 1999
Last sequence update:	November 1, 1996
Last modified:	January 25, 2012
This is version 80 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Drosophila annotation project