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Protein
Submitted name:

Reversed polarity

Gene

repo

Organism
Drosophila melanogaster (Fruit fly)
Status
Unreviewed-Annotation score: Annotation score: 4 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

  • glial cell development Source: FlyBase
  • glial cell differentiation Source: FlyBase
  • nervous system development Source: FlyBase
  • peripheral nervous system development Source: FlyBase
  • positive regulation of gene expression Source: FlyBase
  • positive regulation of transcription from RNA polymerase II promoter Source: GOC
  • regulation of glucose metabolic process Source: FlyBase
  • regulation of phagocytosis Source: FlyBase
  • synapse organization Source: FlyBase
  • synaptic growth at neuromuscular junction Source: FlyBase
  • transcription from RNA polymerase II promoter Source: GOC
Complete GO annotation...

Keywords - Ligandi

DNA-bindingUniRule annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Reversed polarityImported
Gene namesi
Name:repoImported
Synonyms:REPOImported
ORF Names:CG31240Imported
OrganismiDrosophila melanogaster (Fruit fly)
Taxonomic identifieri7227 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraEndopterygotaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora

Organism-specific databases

FlyBaseiFBgn0011701. repo.

Subcellular locationi

  • Nucleus UniRule annotation

GO - Cellular componenti

  • cytoplasm Source: FlyBase
  • nucleus Source: FlyBase
Complete GO annotation...

Keywords - Cellular componenti

NucleusUniRule annotation

PTM / Processingi

Proteomic databases

PaxDbiQ24477.
PRIDEiQ24477.

Expressioni

Gene expression databases

BgeeiQ24477.

Interactioni

Protein-protein interaction databases

STRINGi7227.FBpp0082986.

Structurei

3D structure databases

ProteinModelPortaliQ24477.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini302 – 36261Homeobox DNA-bindingInterPro annotationAdd
BLAST

Keywords - Domaini

HomeoboxUniRule annotation

Phylogenomic databases

eggNOGiKOG0490. Eukaryota.
ENOG410YIJ3. LUCA.
OrthoDBiEOG7XPZ60.

Family and domain databases

Gene3Di1.10.10.60. 1 hit.
InterProiIPR017970. Homeobox_CS.
IPR001356. Homeobox_dom.
IPR009057. Homeodomain-like.
[Graphical view]
PfamiPF00046. Homeobox. 1 hit.
[Graphical view]
SMARTiSM00389. HOX. 1 hit.
[Graphical view]
SUPFAMiSSF46689. SSF46689. 1 hit.
PROSITEiPS00027. HOMEOBOX_1. 1 hit.
PS50071. HOMEOBOX_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q24477-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEHDSFDDPI FGEFGGGPLN PLGAKPLMPT TTAMHPVMLG SVHELCSQQQ
60 70 80 90 100
QQQQQQRLPD CNTILPNAVG GGAGSGGAGG SPNYVTKLDF VNKMGCYSPS
110 120 130 140 150
QKYEYISAPQ KLVEQQQQQQ HHHQHHQHYT ATPPPSHNGI LLHKQSSQQQ
160 170 180 190 200
QQQQQQLVGI LDYHPLNGKL DYSSSPKDQY EPQQLQHLYG GSPHHLDHLD
210 220 230 240 250
HGSDGLLQDS SPVMINGGSA GGKLKKPDEM CSQLEAGGAG VTPPSSSSTV
260 270 280 290 300
VNGTTNGTGN ANSSSSAGVG IQGAAGTAGG VAAPAAKKDG SSSKKKGDPN
310 320 330 340 350
GIKKKKTRTT FTAYQLEELE RAFERAPYPD VFAREELAIK LNLSESRVQV
360 370 380 390 400
WFQNRRAKWR KHEPPRKTGY IKTSTPPTAT LNPGTLAPPF TSYPQTTTVT
410 420 430 440 450
PPGSMDSWTS YQTPYELTPQ FSLLSPAASP YGTYSGQYGA YVHESQLFPM
460 470 480 490 500
RHYEYGSPTR MEMGATTGSV AGNGDESVAN GGSYQTAELQ TAQQQQLADG
510 520 530 540 550
TLVTVHAHQQ QQQQQQQLNG KYLSAEEAKY VHLQCHQSGG GLELSPGASC
560 570 580 590 600
HLVEAQGQHY VTTATGGAAS AGGTSSDDND SGGMQTVIKS EEVSQQQQQQ
610
QGQSYVLPPF LH
Length:612
Mass (Da):65,659
Last modified:November 1, 1996 - v1
Checksum:iA777BBED222374C4
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X78218 mRNA. Translation: CAA55063.1.
PIRiA54282.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X78218 mRNA. Translation: CAA55063.1.
PIRiA54282.

3D structure databases

ProteinModelPortaliQ24477.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi7227.FBpp0082986.

Proteomic databases

PaxDbiQ24477.
PRIDEiQ24477.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Organism-specific databases

FlyBaseiFBgn0011701. repo.

Phylogenomic databases

eggNOGiKOG0490. Eukaryota.
ENOG410YIJ3. LUCA.
OrthoDBiEOG7XPZ60.

Gene expression databases

BgeeiQ24477.

Family and domain databases

Gene3Di1.10.10.60. 1 hit.
InterProiIPR017970. Homeobox_CS.
IPR001356. Homeobox_dom.
IPR009057. Homeodomain-like.
[Graphical view]
PfamiPF00046. Homeobox. 1 hit.
[Graphical view]
SMARTiSM00389. HOX. 1 hit.
[Graphical view]
SUPFAMiSSF46689. SSF46689. 1 hit.
PROSITEiPS00027. HOMEOBOX_1. 1 hit.
PS50071. HOMEOBOX_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "repo encodes a glial-specific homeo domain protein required in the Drosophila nervous system."
    Xiong W.C., Okano H., Patel N.H., Blendy J.A., Montell C.
    Genes Dev. 8:981-994(1994) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.

Entry informationi

Entry nameiQ24477_DROME
AccessioniPrimary (citable) accession number: Q24477
Entry historyi
Integrated into UniProtKB/TrEMBL: November 1, 1996
Last sequence update: November 1, 1996
Last modified: March 16, 2016
This is version 104 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.