Q24474 (Q24474_DROME) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
GH26440p EMBL AAR88559.1

Submitted name:
RNA-binding protein EMBL AAC13646.1
Submitted name:
RNA-binding protein 9, isoform E EMBL AAN10402.1
Submitted name:
RNA-binding protein 9, isoform F EMBL AAN10403.1
Submitted name:
RNA-binding protein 9, isoform G EMBL AAX52651.1
Submitted name:
RNA-binding protein 9, isoform H EMBL AAN10401.3

Gene names

Name:	Rbp9 EMBL AAN10401.3 FlyBase FBgn0010263
Synonyms:	RBP9 EMBL AAC13646.1
ORF Names:	CG3151 FlyBase FBgn0010263, Dmel_CG3151 EMBL AAN10401.3

Organism

Drosophila melanogaster (Fruit fly) [Reference proteome] EMBL AAC13646.1

Taxonomic identifier

7227 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Protostomia › Ecdysozoa › Panarthropoda › Arthropoda › Mandibulata › Pancrustacea › Hexapoda › Insecta › Dicondylia › Pterygota › Neoptera › Endopterygota › Diptera › Brachycera › Muscomorpha › Eremoneura › Cyclorrhapha › Schizophora › Acalyptratae › Ephydroidea › Drosophilidae › Drosophilinae › Drosophilini › Drosophilina › Drosophiliti › Drosophila › Sophophora › melanogaster group › melanogaster subgroup

Protein attributes

Sequence length	439 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

Ontologies

Keywords
Domain	Repeat SAAS SAAS002343
Ligand	RNA-binding SAAS SAAS002343
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	establishment of blood-brain barrier Inferred from mutant phenotype PubMed 20069381. Source: FlyBase germ cell proliferation Inferred from mutant phenotype PubMed 15529000. Source: FlyBase germarium-derived egg chamber formation Traceable author statement PubMed 11744369. Source: FlyBase
Cellular_component	nucleus Traceable author statement PubMed 9642172. Source: FlyBase
Molecular_function	mRNA 3'-UTR binding Traceable author statement PubMed 11131529. Source: FlyBase nucleotide binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q24474 [UniParc]. Last modified November 1, 1996. Version 1. Checksum: 47FF65ACFFD950D1	FASTA	439	46,245
	10 20 30 40 50 60 MVEGQTAVQQ QQQQPSGAGG ASGVGSTTGS AGGPATANNV TNSQAQTNGG TTATTTAAAG 70 80 90 100 110 120 AGSTTNAAVG QATANNAASN NNNNNNNTNN NNNNNATANN NNNNEPDPKT NLIVNYLPQT 130 140 150 160 170 180 MSQDEIRSLF VSFGEVESCK LIRDKVTGQS LGYGFVNYVK QEDAEKAINA LNGLRLQNKT 190 200 210 220 230 240 IKVSIARPSS ESIKGANLYV SGLPKNMTQS DLESLFSPYG KIITSRILCD NITGLSKGVG 250 260 270 280 290 300 FIRFDQRFEA DRAIKELNGT TPKNSTEPIT VKFANNPSSN KNSMQPLAAY IAPQNTRGGR 310 320 330 340 350 360 AFPANAAAGA AAAAAAAAIH PNAGRYSSVI SRYSPLTSDL ITNGMIQGNT IASSGWCIFV 370 380 390 400 410 420 YNLAPDTEEN VLWQLFGPFG AVQSVKVIRD LQSNKCKGFG FVTMTNYEEA VLAIQSLNGY 430 TLGNRVLQVS FKTNKNKQT

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"The Drosophila gene rbp9 encodes a protein that is a member of a conserved group of putative RNA binding proteins that are nervous system-specific inBoth flies and humans." Kim Y.-J., Baker B.S. J. Neurosci. 0:0-0(1992) Cited for: NUCLEOTIDE SEQUENCE. Strain: Canton S EMBL AAC13646.1.
[2]	"The genome sequence of Drosophila melanogaster." Adams M.D., Celniker S.E., Holt R.A., Evans C.A., Gocayne J.D., Amanatides P.G., Scherer S.E., Li P.W., Hoskins R.A., Galle R.F., George R.A., Lewis S.E., Richards S., Ashburner M., Henderson S.N., Sutton G.G., Wortman J.R., Yandell M.D. , Zhang Q., Chen L.X., Brandon R.C., Rogers Y.H., Blazej R.G., Champe M., Pfeiffer B.D., Wan K.H., Doyle C., Baxter E.G., Helt G., Nelson C.R., Gabor G.L., Abril J.F., Agbayani A., An H.J., Andrews-Pfannkoch C., Baldwin D., Ballew R.M., Basu A., Baxendale J., Bayraktaroglu L., Beasley E.M., Beeson K.Y., Benos P.V., Berman B.P., Bhandari D., Bolshakov S., Borkova D., Botchan M.R., Bouck J., Brokstein P., Brottier P., Burtis K.C., Busam D.A., Butler H., Cadieu E., Center A., Chandra I., Cherry J.M., Cawley S., Dahlke C., Davenport L.B., Davies P., de Pablos B., Delcher A., Deng Z., Mays A.D., Dew I., Dietz S.M., Dodson K., Doup L.E., Downes M., Dugan-Rocha S., Dunkov B.C., Dunn P., Durbin K.J., Evangelista C.C., Ferraz C., Ferriera S., Fleischmann W., Fosler C., Gabrielian A.E., Garg N.S., Gelbart W.M., Glasser K., Glodek A., Gong F., Gorrell J.H., Gu Z., Guan P., Harris M., Harris N.L., Harvey D., Heiman T.J., Hernandez J.R., Houck J., Hostin D., Houston K.A., Howland T.J., Wei M.H., Ibegwam C., Jalali M., Kalush F., Karpen G.H., Ke Z., Kennison J.A., Ketchum K.A., Kimmel B.E., Kodira C.D., Kraft C., Kravitz S., Kulp D., Lai Z., Lasko P., Lei Y., Levitsky A.A., Li J., Li Z., Liang Y., Lin X., Liu X., Mattei B., McIntosh T.C., McLeod M.P., McPherson D., Merkulov G., Milshina N.V., Mobarry C., Morris J., Moshrefi A., Mount S.M., Moy M., Murphy B., Murphy L., Muzny D.M., Nelson D.L., Nelson D.R., Nelson K.A., Nixon K., Nusskern D.R., Pacleb J.M., Palazzolo M., Pittman G.S., Pan S., Pollard J., Puri V., Reese M.G., Reinert K., Remington K., Saunders R.D., Scheeler F., Shen H., Shue B.C., Siden-Kiamos I., Simpson M., Skupski M.P., Smith T., Spier E., Spradling A.C., Stapleton M., Strong R., Sun E., Svirskas R., Tector C., Turner R., Venter E., Wang A.H., Wang X., Wang Z.Y., Wassarman D.A., Weinstock G.M., Weissenbach J., Williams S.M., WoodageT, Worley K.C., Wu D., Yang S., Yao Q.A., Ye J., Yeh R.F., Zaveri J.S., Zhan M., Zhang G., Zhao Q., Zheng L., Zheng X.H., Zhong F.N., Zhong W., Zhou X., Zhu S., Zhu X., Smith H.O., Gibbs R.A., Myers E.W., Rubin G.M., Venter J.C. Science 287:2185-2195(2000) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Berkeley.
[3]	"Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence." Celniker S.E., Wheeler D.A., Kronmiller B., Carlson J.W., Halpern A., Patel S., Adams M., Champe M., Dugan S.P., Frise E., Hodgson A., George R.A., Hoskins R.A., Laverty T., Muzny D.M., Nelson C.R., Pacleb J.M., Park S. , Pfeiffer B.D., Richards S., Sodergren E.J., Svirskas R., Tabor P.E., Wan K., Stapleton M., Sutton G.G., Venter C., Weinstock G., Scherer S.E., Myers E.W., Gibbs R.A., Rubin G.M. Genome Biol. 3:RESEARCH0079-RESEARCH0079(2002) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE.
[4]	"Annotation of the Drosophila melanogaster euchromatic genome: a systematic review." Misra S., Crosby M.A., Mungall C.J., Matthews B.B., Campbell K.S., Hradecky P., Huang Y., Kaminker J.S., Millburn G.H., Prochnik S.E., Smith C.D., Tupy J.L., Whitfied E.J., Bayraktaroglu L., Berman B.P., Bettencourt B.R., Celniker S.E., de Grey A.D. , Drysdale R.A., Harris N.L., Richter J., Russo S., Schroeder A.J., Shu S.Q., Stapleton M., Yamada C., Ashburner M., Gelbart W.M., Rubin G.M., Lewis S.E. Genome Biol. 3:RESEARCH0083-RESEARCH0083(2002) [PubMed] [Europe PMC] [Abstract] Cited for: GENOME REANNOTATION. Strain: Berkeley.
[5]	"The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective." Kaminker J.S., Bergman C.M., Kronmiller B., Carlson J., Svirskas R., Patel S., Frise E., Wheeler D.A., Lewis S.E., Rubin G.M., Ashburner M., Celniker S.E. Genome Biol. 3:RESEARCH0084-RESEARCH0084(2002) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE.
[6]	"Heterochromatic sequences in a Drosophila whole-genome shotgun assembly." Hoskins R.A., Smith C.D., Carlson J.W., Carvalho A.B., Halpern A., Kaminker J.S., Kennedy C., Mungall C.J., Sullivan B.A., Sutton G.G., Yasuhara J.C., Wakimoto B.T., Myers E.W., Celniker S.E., Rubin G.M., Karpen G.H. Genome Biol. 3:RESEARCH0085-RESEARCH0085(2002) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE.
[7]	Stapleton M., Brokstein P., Hong L., Agbayani A., Carlson J., Champe M., Chavez C., Dorsett V., Dresnek D., Farfan D., Frise E., George R., Gonzalez M., Guarin H., Kronmiller B., Li P., Liao G., Miranda A. , Mungall C.J., Nunoo J., Pacleb J., Paragas V., Park S., Patel S., Phouanenavong S., Wan K., Yu C., Lewis S.E., Rubin G.M., Celniker S. Submitted (JAN-2004) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Strain: Berkeley EMBL AAR88559.1.
[8]	"Combined evidence annotation of transposable elements in genome sequences." Quesneville H., Bergman C.M., Andrieu O., Autard D., Nouaud D., Ashburner M., Anxolabehere D. PLoS Comput. Biol. 1:166-175(2005) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE.
[9]	Celniker S., Carlson J., Wan K., Frise E., Hoskins R., Park S., Svirskas R., Rubin G. Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.
[10]	"Drosophila melanogaster release 4 sequence." Berkeley Drosophila Genome Project Celniker S., Carlson J., Wan K., Pfeiffer B., Frise E., George R., Hoskins R., Stapleton M., Pacleb J., Park S., Svirskas R., Smith E., Yu C., Rubin G. Submitted (SEP-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.
[11]	"The Release 5.1 annotation of Drosophila melanogaster heterochromatin." Smith C.D., Shu S., Mungall C.J., Karpen G.H. Science 316:1586-1591(2007) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE.
[12]	"Sequence finishing and mapping of Drosophila melanogaster heterochromatin." Hoskins R.A., Carlson J.W., Kennedy C., Acevedo D., Evans-Holm M., Frise E., Wan K.H., Park S., Mendez-Lago M., Rossi F., Villasante A., Dimitri P., Karpen G.H., Celniker S.E. Science 316:1625-1628(2007) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE.
[13]	FlyBase Submitted (DEC-2009) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	L04930 Genomic DNA. Translation: AAC13646.1. AE014134 Genomic DNA. Translation: AAN10401.3. AE014134 Genomic DNA. Translation: AAN10402.1. AE014134 Genomic DNA. Translation: AAN10403.1. BT011197 mRNA. Translation: AAR88559.1. AE014134 Genomic DNA. Translation: AAX52651.1.
RefSeq	NP_001014462.1. NM_001014462.3. NP_476936.3. NM_057588.3. NP_599125.1. NM_134298.5. NP_599126.1. NM_134299.5.
UniGene	Dm.4071.
3D structure databases
SMR	Q24474. Positions 62-274, 355-436.
ModBase	Search...
Protein-protein interaction databases
IntAct	Q24474. 2 interactions.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblMetazoa	FBtr0077638; FBpp0077323; FBgn0010263. FBtr0077640; FBpp0077325; FBgn0010263. FBtr0100468; FBpp0099898; FBgn0010263. FBtr0290237; FBpp0288676; FBgn0010263.
GeneID	33498.
KEGG	dme:Dmel_CG3151.
UCSC	CG3151-RE. d. melanogaster.
Organism-specific databases
CTD	33498.
FlyBase	FBgn0010263. Rbp9.
Phylogenomic databases
GeneTree	ENSGT00560000077064.
HOGENOM	HOG000114767.
InParanoid	Q24474.
KO	K13208.
OrthoDB	EOG46DJK7.
Family and domain databases
Gene3D	3.30.70.330. 3 hits.
InterPro	IPR006548. ELAD_HUD_SF. IPR002343. Hud_Sxl_RNA. IPR012677. Nucleotide-bd_a/b_plait. IPR000504. RRM_dom. [Graphical view]
Pfam	PF00076. RRM_1. 3 hits. [Graphical view]
PRINTS	PR00961. HUDSXLRNA.
SMART	SM00360. RRM. 3 hits. [Graphical view]
TIGRFAMs	TIGR01661. ELAV_HUD_SF. 1 hit.
PROSITE	PS50102. RRM. 3 hits. [Graphical view]
ProtoNet	Search...
Other
GenomeRNAi	33498.
NextBio	783890.

Entry information

Entry name

Q24474_DROME

Accession

Primary (citable) accession number: Q24474
Secondary accession number(s): Q7KU26

Entry history

Integrated into UniProtKB/TrEMBL:	November 1, 1996
Last sequence update:	November 1, 1996
Last modified:	May 29, 2013
This is version 111 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)