Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

40S ribosomal protein S5a

Gene

RpS5a

Organism
Drosophila melanogaster (Fruit fly)
Status
Reviewed-Annotation score: Annotation score: 4 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  • mRNA binding Source: GO_Central
  • rRNA binding Source: GO_Central
  • structural constituent of ribosome Source: FlyBase

GO - Biological processi

  • cytoplasmic translation Source: FlyBase
  • ribosomal small subunit assembly Source: GO_Central

Keywordsi

Molecular functionRibonucleoprotein, Ribosomal protein

Enzyme and pathway databases

ReactomeiR-DME-156827. L13a-mediated translational silencing of Ceruloplasmin expression.
R-DME-1799339. SRP-dependent cotranslational protein targeting to membrane.
R-DME-6791226. Major pathway of rRNA processing in the nucleolus and cytosol.
R-DME-72649. Translation initiation complex formation.
R-DME-72689. Formation of a pool of free 40S subunits.
R-DME-72695. Formation of the ternary complex, and subsequently, the 43S complex.
R-DME-72702. Ribosomal scanning and start codon recognition.
R-DME-72706. GTP hydrolysis and joining of the 60S ribosomal subunit.
R-DME-975956. Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC).
R-DME-975957. Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC).

Names & Taxonomyi

Protein namesi
Recommended name:
40S ribosomal protein S5a
Gene namesi
Name:RpS5a
Synonyms:M(1)15D, RpS5
ORF Names:CG8922
OrganismiDrosophila melanogaster (Fruit fly)
Taxonomic identifieri7227 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
Proteomesi
  • UP000000803 Componenti: Chromosome X

Organism-specific databases

FlyBaseiFBgn0002590. RpS5a.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001245301 – 22840S ribosomal protein S5aAdd BLAST228

Proteomic databases

PaxDbiQ24186.
PRIDEiQ24186.

Expressioni

Gene expression databases

BgeeiFBgn0002590.
GenevisibleiQ24186. DM.

Interactioni

Protein-protein interaction databases

BioGridi59029. 24 interactors.
DIPiDIP-18111N.
IntActiQ24186. 2 interactors.
MINTiMINT-960786.
STRINGi7227.FBpp0074180.

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
4V6Welectron microscopy6.00AF1-228[»]
ProteinModelPortaliQ24186.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiKOG3291. Eukaryota.
COG0049. LUCA.
InParanoidiQ24186.
KOiK02989.
OMAiDSLMMKG.
OrthoDBiEOG091G0KXZ.
PhylomeDBiQ24186.

Family and domain databases

CDDicd14867. uS7_Eukaryote. 1 hit.
Gene3Di1.10.455.10. 1 hit.
InterProiView protein in InterPro
IPR000235. Ribosomal_S5/S7.
IPR005716. Ribosomal_S5/S7_euk/arc.
IPR020606. Ribosomal_S7_CS.
IPR023798. Ribosomal_S7_dom.
IPR036823. Ribosomal_S7_dom_sf.
PANTHERiPTHR11205. PTHR11205. 1 hit.
PfamiView protein in Pfam
PF00177. Ribosomal_S7. 1 hit.
PIRSFiPIRSF002122. RPS7p_RPS7a_RPS5e_RPS7o. 1 hit.
SUPFAMiSSF47973. SSF47973. 1 hit.
TIGRFAMsiTIGR01028. uS7_euk_arch. 1 hit.
PROSITEiView protein in PROSITE
PS00052. RIBOSOMAL_S7. 1 hit.

Sequencei

Sequence statusi: Complete.

Q24186-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAEVAENVVE TFEEPAAPME AEVAETILET NVVSTTELPE IKLFGRWSCD
60 70 80 90 100
DVTVNDISLQ DYISVKEKFA RYLPHSAGRY AAKRFRKAQC PIVERLTCSL
110 120 130 140 150
MMKGRNNGKK LMACRIVKHS FEIIHLLTGE NPLQILVSAI INSGPREDST
160 170 180 190 200
RIGRAGTVRR QAVDVSPLRR VNQAIWLLCT GAREAAFRNI KTIAECLADE
210 220
LINAAKGSSN SYAIKKKDEL ERVAKSNR
Length:228
Mass (Da):25,434
Last modified:November 1, 1996 - v1
Checksum:i9206E1D8FE470C4C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U48394 mRNA. Translation: AAB61633.1.
AE014298 Genomic DNA. Translation: AAF48700.1.
AY075368 mRNA. Translation: AAL68215.1.
RefSeqiNP_001285360.1. NM_001298431.1.
NP_001285361.1. NM_001298432.1.
NP_001285362.1. NM_001298433.1.
NP_523382.1. NM_078658.3.
UniGeneiDm.2690.

Genome annotation databases

EnsemblMetazoaiFBtr0074406; FBpp0074180; FBgn0002590.
FBtr0343292; FBpp0309957; FBgn0002590.
FBtr0343293; FBpp0309958; FBgn0002590.
FBtr0345132; FBpp0311353; FBgn0002590.
GeneIDi32700.
KEGGidme:Dmel_CG8922.

Similar proteinsi

Entry informationi

Entry nameiRS5A_DROME
AccessioniPrimary (citable) accession number: Q24186
Secondary accession number(s): Q9VX78
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: November 1, 1996
Last modified: October 25, 2017
This is version 129 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programDrosophila annotation project

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. Drosophila
    Drosophila: entries, gene names and cross-references to FlyBase
  2. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  3. Ribosomal proteins
    Ribosomal proteins families and list of entries
  4. SIMILARITY comments
    Index of protein domains and families