Q24173 (Q24173_DROME) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Beta subunit of type I geranylgeranyl transferase EMBL AAF52177.1
EC=2.5.1.- EMBL AAF52177.1
EC=2.5.1.59 EMBL AAF52177.1

Submitted name:
Geranylgeranyl transferase beta-subunit type I EMBL AAC46972.1
Submitted name:
SD20823p EMBL AAM51106.1

Gene names

Name:	betaggt-I FlyBase FBgn0015000 EMBL AAM51106.1
Synonyms:	<beta>ggt-I EMBL AAC46972.1, beta-ggt-I FlyBase FBgn0015000
ORF Names:	CG3469 FlyBase FBgn0015000, Dmel_CG3469 EMBL AAF52177.1

Organism

Drosophila melanogaster (Fruit fly)

Taxonomic identifier

7227 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Arthropoda › Hexapoda › Insecta › Pterygota › Neoptera › Endopterygota › Diptera › Brachycera › Muscomorpha › Ephydroidea › Drosophilidae › Drosophila › Sophophora

Protein attributes

Sequence length	395 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

Ontologies

Keywords
Domain	Repeat SAAS SAAS008930
Molecular function	Transferase EMBL AAF52177.1
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	embryonic heart tube development Inferred from mutant phenotype. Source: FlyBase
Molecular function	CAAX-protein geranylgeranyltransferase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q24173 [UniParc]. Last modified November 1, 1996. Version 1. Checksum: 4A3C5A76A7D5B4A0	FASTA	395	44,110
	10 20 30 40 50 60 MEDRTDTEPV LLSKHAKNLL RFLNLLPARM ASHDNTRSTI VFFAVCGLDV LNSLHLVPPQ 70 80 90 100 110 120 LRQDIIDWIY GGLVVPRDNE KNCGGFMGCR AMVPKTEDAE ILECMRNYQW GHLAMTYTSL 130 140 150 160 170 180 AVLVTLGDDL SRLDRKSIVD GVAAVQKPEG SFSACIDGSE DDMRFVYCAA TICYMLDYWG 190 200 210 220 230 240 DVNKETMFQF ITRSLRYDYG FSQELEGEAH GGTTFCALAA LHLSGQLHRL DATTVERMKR 250 260 270 280 290 300 WLIFRQMDGF QGRPNKPVDT CYSFWIGASL CILDGFELTD YARNREFILS TQDKLIGGFA 310 320 330 340 350 360 KWPQATPDPF HTYLGLCGLA FTGEPGLSPV NPSLNMSMAA YAHLQHLHEQ WRSADGRGDE 370 380 390 DISVSSAFKQ QLHLSKGVEA TSTTTTSNSP LISAQ

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"The genome sequence of Drosophila melanogaster." Adams M.D., Celniker S.E., Holt R.A., Evans C.A., Gocayne J.D., Amanatides P.G., Scherer S.E., Li P.W., Hoskins R.A., Galle R.F., George R.A., Lewis S.E., Richards S., Ashburner M., Henderson S.N., Sutton G.G., Wortman J.R., Yandell M.D. , Zhang Q., Chen L.X., Brandon R.C., Rogers Y.H., Blazej R.G., Champe M., Pfeiffer B.D., Wan K.H., Doyle C., Baxter E.G., Helt G., Nelson C.R., Gabor G.L., Abril J.F., Agbayani A., An H.J., Andrews-Pfannkoch C., Baldwin D., Ballew R.M., Basu A., Baxendale J., Bayraktaroglu L., Beasley E.M., Beeson K.Y., Benos P.V., Berman B.P., Bhandari D., Bolshakov S., Borkova D., Botchan M.R., Bouck J., Brokstein P., Brottier P., Burtis K.C., Busam D.A., Butler H., Cadieu E., Center A., Chandra I., Cherry J.M., Cawley S., Dahlke C., Davenport L.B., Davies P., de Pablos B., Delcher A., Deng Z., Mays A.D., Dew I., Dietz S.M., Dodson K., Doup L.E., Downes M., Dugan-Rocha S., Dunkov B.C., Dunn P., Durbin K.J., Evangelista C.C., Ferraz C., Ferriera S., Fleischmann W., Fosler C., Gabrielian A.E., Garg N.S., Gelbart W.M., Glasser K., Glodek A., Gong F., Gorrell J.H., Gu Z., Guan P., Harris M., Harris N.L., Harvey D., Heiman T.J., Hernandez J.R., Houck J., Hostin D., Houston K.A., Howland T.J., Wei M.H., Ibegwam C., Jalali M., Kalush F., Karpen G.H., Ke Z., Kennison J.A., Ketchum K.A., Kimmel B.E., Kodira C.D., Kraft C., Kravitz S., Kulp D., Lai Z., Lasko P., Lei Y., Levitsky A.A., Li J., Li Z., Liang Y., Lin X., Liu X., Mattei B., McIntosh T.C., McLeod M.P., McPherson D., Merkulov G., Milshina N.V., Mobarry C., Morris J., Moshrefi A., Mount S.M., Moy M., Murphy B., Murphy L., Muzny D.M., Nelson D.L., Nelson D.R., Nelson K.A., Nixon K., Nusskern D.R., Pacleb J.M., Palazzolo M., Pittman G.S., Pan S., Pollard J., Puri V., Reese M.G., Reinert K., Remington K., Saunders R.D., Scheeler F., Shen H., Shue B.C., Siden-Kiamos I., Simpson M., Skupski M.P., Smith T., Spier E., Spradling A.C., Stapleton M., Strong R., Sun E., Svirskas R., Tector C., Turner R., Venter E., Wang A.H., Wang X., Wang Z.Y., Wassarman D.A., Weinstock G.M., Weissenbach J., Williams S.M., WoodageT, Worley K.C., Wu D., Yang S., Yao Q.A., Ye J., Yeh R.F., Zaveri J.S., Zhan M., Zhang G., Zhao Q., Zheng L., Zheng X.H., Zhong F.N., Zhong W., Zhou X., Zhu S., Zhu X., Smith H.O., Gibbs R.A., Myers E.W., Rubin G.M., Venter J.C. Science 287:2185-2195(2000) [PubMed: 10731132] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Berkeley.
[2]	"KSR, a novel protein kinase required for RAS signal transduction." Therrien M., Chang H.C., Solomon N.M., Karim F.D., Wassarman D.A., Rubin G.M. Cell 83:879-888(1995) [PubMed: 8521512] [Abstract] Cited for: NUCLEOTIDE SEQUENCE.
[3]	"Annotation of the Drosophila melanogaster euchromatic genome: a systematic review." Misra S., Crosby M.A., Mungall C.J., Matthews B.B., Campbell K.S., Hradecky P., Huang Y., Kaminker J.S., Millburn G.H., Prochnik S.E., Smith C.D., Tupy J.L., Whitfield E.J., Bayraktaroglu L., Berman B.P., Bettencourt B.R., Celniker S.E., de Grey A.D.N.J. , Drysdale R.A., Harris N.L., Richter J., Russo S., Schroeder A.J., Shu S.Q., Stapleton M., Yamada C., Ashburner M., Gelbart W.M., Rubin G.M., Lewis S.E. Genome Biol. 3:RESEARCH0083.1-RESEARCH0083.22(2002) [PubMed: 12537572] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: Berkeley.
[4]	Stapleton M., Carlson J., Frise E., Kapadia B., Park S., Wan K., Yu C., Celniker S. Submitted (NOV-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	U43588 Genomic DNA. Translation: AAC46972.1. AE014134 Genomic DNA. Translation: AAF52177.1. AY119246 mRNA. Translation: AAM51106.1.
RefSeq	NP_525100.2. NM_080361.2.
UniGene	Dm.12506.
3D structure databases
HSSP	HSSP built from PDB template 1N4P based on UniProtKB P53610.
ProteinModelPortal	Q24173.
SMR	Q24173. Positions 9-353.
ModBase	Search...
Protein-protein interaction databases
MINT	MINT-928499.
STRING	Q24173.
Proteomic databases
PRIDE	Q24173.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblMetazoa	FBtr0078991; FBpp0078630; FBgn0015000.
GeneID	33704.
KEGG	dme:Dmel_CG3469.
NMPDR	fig|7227.3.peg.786.
UCSC	CG3469-RA. d. melanogaster.
Organism-specific databases
CTD	33704.
FlyBase	FBgn0015000. betaggt-I.
Phylogenomic databases
GeneTree	EMGT00050000009112.
InParanoid	Q24173.
OMA	HGGTTFC.
PhylomeDB	Q24173.
Gene expression databases
ArrayExpress	Q24173.
Bgee	Q24173.
Family and domain databases
InterPro	IPR001330. Prenyltrans. IPR008930. Terpenoid_cyclase/PrenylTrfase. [Graphical view]
KO	K11713.
Pfam	PF00432. Prenyltrans. 2 hits. [Graphical view]
SUPFAM	SSF48239. Terp_cyc_toroid. 1 hit.
ProtoNet	Search...
Other
NextBio	784871.

Entry information

Entry name

Q24173_DROME

Accession

Primary (citable) accession number: Q24173

Entry history

Integrated into UniProtKB/TrEMBL:	November 1, 1996
Last sequence update:	November 1, 1996
Last modified:	January 25, 2012
This is version 91 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)