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Protein
Submitted name:

Neuron specific zinc finger transcription factor

Gene

scrt

Organism
Drosophila melanogaster (Fruit fly)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

  • dendrite morphogenesis Source: FlyBase
  • negative regulation of transcription from RNA polymerase II promoter Source: FlyBase
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Neuron specific zinc finger transcription factorImported
Gene namesi
Name:scrtImported
ORF Names:CG1130Imported
OrganismiDrosophila melanogaster (Fruit fly)
Taxonomic identifieri7227 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraEndopterygotaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora

Organism-specific databases

FlyBaseiFBgn0004880. scrt.

PTM / Processingi

Proteomic databases

PaxDbiQ24140.
PRIDEiQ24140.

Expressioni

Gene expression databases

BgeeiQ24140.
ExpressionAtlasiQ24140. differential.

Interactioni

Protein-protein interaction databases

STRINGi7227.FBpp0305342.

Structurei

3D structure databases

ProteinModelPortaliQ24140.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini467 – 49428C2H2-typeInterPro annotationAdd
BLAST
Domaini496 – 52328C2H2-typeInterPro annotationAdd
BLAST
Domaini522 – 54928C2H2-typeInterPro annotationAdd
BLAST
Domaini550 – 57728C2H2-typeInterPro annotationAdd
BLAST
Domaini578 – 60730C2H2-typeInterPro annotationAdd
BLAST

Phylogenomic databases

eggNOGiKOG2462. Eukaryota.
ENOG41106JS. LUCA.
HOGENOMiHOG000006056.
OrthoDBiEOG7P2XSG.

Family and domain databases

Gene3Di3.30.160.60. 3 hits.
InterProiIPR007087. Znf_C2H2.
IPR015880. Znf_C2H2-like.
IPR013087. Znf_C2H2/integrase_DNA-bd.
[Graphical view]
PfamiPF00096. zf-C2H2. 1 hit.
[Graphical view]
SMARTiSM00355. ZnF_C2H2. 5 hits.
[Graphical view]
PROSITEiPS00028. ZINC_FINGER_C2H2_1. 4 hits.
PS50157. ZINC_FINGER_C2H2_2. 5 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q24140-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPRCLIAKKW KAYPWLDRTE DTCNQQQQQE QSAPNSPREL EELHLKSRRS
60 70 80 90 100
TLDDDEEIDV VGDKFLIKLE KQRTTADAAA AAATSSEAAT SHSSNSSNME
110 120 130 140 150
ASATTTTSKC WGPSSPTAGT TAPSPPPHSP EAATRVAGNV YNGYTRELSP
160 170 180 190 200
LHYTAYLPRM ESEITVIRAA ATALVAARTS GNGSGDQHLA VYQTPPSSTT
210 220 230 240 250
SSPSCSPSGA GDRYSPLSSG QTSSERKCFS STGATLSLPP KKKDIYRPYS
260 270 280 290 300
LDDKPAHGYR RRVPAEEDLH AAHAILDLSA STAFHPPTQP HQLQQQQQQQ
310 320 330 340 350
QQQHQHHHSQ QQHLAPQQHH YLPLQQQQQQ QAHHTHLPTL EAHAHLRSTS
360 370 380 390 400
SIAELAAAAS VVNEQRPASN ASSASSNHMP SSPSSNSSSS SSQVQNENSN
410 420 430 440 450
TTNTNQDGDG CLQDGEHNGA SGASAKTVAY TYEAFFVSDG RSKRKHVADP
460 470 480 490 500
AAAASGVPTP DQQKTKYTCS ECGKQYATSS NLSRHKQTHV DSQSAKKCHT
510 520 530 540 550
CGKAYVSMPA LAMHLLTHKL SHSCGVCGKL FSRPWLLQGH LRSHTGEKPY
560 570 580 590 600
GCAHCGKAFA DRSNLRAHMQ THSVDKNFEC KRCHKTFALK SYLNKHLESA
610 620 630 640 650
CLKDEEELMM SMSLSMHDSN SESGASMASS PPHEFLEARQ TRRAVEEPLM
660
PCKHRIHWAR YRNL
Length:664
Mass (Da):72,569
Last modified:November 1, 1996 - v1
Checksum:i687F2DAABFE8968F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U36477 mRNA. Translation: AAA91035.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U36477 mRNA. Translation: AAA91035.1.

3D structure databases

ProteinModelPortaliQ24140.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi7227.FBpp0305342.

Proteomic databases

PaxDbiQ24140.
PRIDEiQ24140.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Organism-specific databases

FlyBaseiFBgn0004880. scrt.

Phylogenomic databases

eggNOGiKOG2462. Eukaryota.
ENOG41106JS. LUCA.
HOGENOMiHOG000006056.
OrthoDBiEOG7P2XSG.

Gene expression databases

BgeeiQ24140.
ExpressionAtlasiQ24140. differential.

Family and domain databases

Gene3Di3.30.160.60. 3 hits.
InterProiIPR007087. Znf_C2H2.
IPR015880. Znf_C2H2-like.
IPR013087. Znf_C2H2/integrase_DNA-bd.
[Graphical view]
PfamiPF00096. zf-C2H2. 1 hit.
[Graphical view]
SMARTiSM00355. ZnF_C2H2. 5 hits.
[Graphical view]
PROSITEiPS00028. ZINC_FINGER_C2H2_1. 4 hits.
PS50157. ZINC_FINGER_C2H2_2. 5 hits.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "scratch, a pan-neural gene encoding a zinc finger protein related to snail, promotes neuronal development."
    Roark M., Sturtevant M.A., Emery J., Vaessin H., Grell E., Bier E.
    Genes Dev. 9:2384-2398(1995) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.

Entry informationi

Entry nameiQ24140_DROME
AccessioniPrimary (citable) accession number: Q24140
Entry historyi
Integrated into UniProtKB/TrEMBL: November 1, 1996
Last sequence update: November 1, 1996
Last modified: March 16, 2016
This is version 96 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.