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Protein
Submitted name:

Transcription factor

Gene

shn

Organism
Drosophila melanogaster (Fruit fly)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  • DNA binding transcription factor activity Source: FlyBase
  • nucleic acid binding Source: InterPro
  • RNA polymerase II activating transcription factor binding Source: FlyBase
  • RNA polymerase II transcription coactivator activity Source: FlyBase
  • transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding Source: FlyBase
  • zinc ion binding Source: InterPro

GO - Biological processi

  • cell proliferation Source: FlyBase
  • compound eye morphogenesis Source: FlyBase
  • dendrite morphogenesis Source: FlyBase
  • dorsal closure Source: FlyBase
  • ectoderm development Source: FlyBase
  • imaginal disc-derived wing morphogenesis Source: FlyBase
  • imaginal disc-derived wing vein morphogenesis Source: FlyBase
  • Malpighian tubule morphogenesis Source: FlyBase
  • midgut development Source: FlyBase
  • negative regulation of cell proliferation Source: FlyBase
  • negative regulation of salivary gland boundary specification Source: FlyBase
  • negative regulation of transcription by RNA polymerase II Source: FlyBase
  • peripheral nervous system development Source: FlyBase
  • positive regulation of transcription by RNA polymerase II Source: FlyBase
  • transforming growth factor beta receptor signaling pathway Source: FlyBase
  • wing disc anterior/posterior pattern formation Source: FlyBase
  • wing disc dorsal/ventral pattern formation Source: FlyBase

Keywordsi

LigandMetal-binding, Zinc

Names & Taxonomyi

Protein namesi
Submitted name:
Transcription factorImported
Gene namesi
Name:shnImported
ORF Names:CG7734Imported
OrganismiDrosophila melanogaster (Fruit fly)Imported
Taxonomic identifieri7227 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora

Organism-specific databases

FlyBaseiFBgn0003396 shn

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Proteomic databases

PRIDEiQ24107

Expressioni

Gene expression databases

BgeeiFBgn0003396
ExpressionAtlasiQ24107 differential

Interactioni

GO - Molecular functioni

  • RNA polymerase II activating transcription factor binding Source: FlyBase

Protein-protein interaction databases

IntActiQ24107, 1 interactor

Structurei

3D structure databases

ProteinModelPortaliQ24107
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini434 – 461C2H2-typeInterPro annotationAdd BLAST28
Domaini462 – 491C2H2-typeInterPro annotationAdd BLAST30
Domaini1054 – 1084CCHC HIVEP-typeInterPro annotationAdd BLAST31
Domaini1766 – 1793C2H2-typeInterPro annotationAdd BLAST28
Domaini1794 – 1818C2H2-typeInterPro annotationAdd BLAST25
Domaini2256 – 2283C2H2-typeInterPro annotationAdd BLAST28
Domaini2284 – 2313C2H2-typeInterPro annotationAdd BLAST30
Domaini2329 – 2358C2H2-typeInterPro annotationAdd BLAST30

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili603 – 632Sequence analysisAdd BLAST30

Keywords - Domaini

Coiled coilSequence analysis, Zinc-fingerPROSITE-ProRule annotationSAAS annotation

Phylogenomic databases

eggNOGiKOG1721 Eukaryota
COG5048 LUCA
OrthoDBiEOG091G02DY

Family and domain databases

InterProiView protein in InterPro
IPR003604 Matrin/U1-like-C_Znf_C2H2
IPR034729 ZF_CCHC_HIVEP
IPR036236 Znf_C2H2_sf
IPR013087 Znf_C2H2_type
SMARTiView protein in SMART
SM00355 ZnF_C2H2, 8 hits
SM00451 ZnF_U1, 4 hits
SUPFAMiSSF57667 SSF57667, 4 hits
PROSITEiView protein in PROSITE
PS51811 ZF_CCHC_HIVEP, 1 hit
PS00028 ZINC_FINGER_C2H2_1, 7 hits
PS50157 ZINC_FINGER_C2H2_2, 7 hits

Sequencei

Sequence statusi: Complete.

Q24107-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MENATTTTAK HYKTAGKQYK TNKVNNTRRA TAAAAAAATT TVTTAATPTK
60 70 80 90 100
KRTYRETATA TTVTQRSTNK ANIAAAIALA AATEATASAS ASATATATDA
110 120 130 140 150
TLTASKAAAT AAATTDAASG NSNSSSKPST STRDKLGEVP LPTVDSNHII
160 170 180 190 200
SNNNNNNNNN NTSNNNNNNH HSDNSISENN YEFKSRDKAS LSDSKMTLQQ
210 220 230 240 250
MAAVSSNQEP VAPNVANTMS NSSIINSQQT TVNATPATDE APLGDRSNIS
260 270 280 290 300
RYLHKKFKRL ASTTEVDSWS ATNGGGALQA SGDAVRTTSL SSNSSLSPPP
310 320 330 340 350
TTPLANGHHL MTQQQSHQQV QQQQQQQTPP PSVAIHEFSA NFVNSNHVNA
360 370 380 390 400
IGHEESIISN SGYKAAGRTR TPLANSNSNT NSTSNSNSNH AANATLSPAS
410 420 430 440 450
FAQHQQLTQP TTVSPGIPGG AAAPNPACEK SGRYVCQYCN LICAKPSVLE
460 470 480 490 500
KHIRAHTNER PYPCDTCGIA FKTKSNLYKH CRSRSHAARA RGLEVPADAD
510 520 530 540 550
DGLSDQDAEL SNSSSELPSR AGSPYEEPIN SPTPSPSTLS AAKSAYIQQP
560 570 580 590 600
PLPTYMQQLP LGSPAAGTLP PTTADNHHSA TAQHRQSIDY KPYKPKFHNA
610 620 630 640 650
SMYSCSSKEL QQQQQQLQIQ QQQQQHQLAQ QKLSIQLPLV QQPSLAHPTL
660 670 680 690 700
SPSTQMKMKH HINSHQIQLQ LQQQQSLLAQ QSLLAAMPPG GVYYLGQPSY
710 720 730 740 750
YNQDTAAAIH QHALAIQQFQ IHLAQQQQQQ QQQHPPLVKA TPPMQQPPSL
760 770 780 790 800
PPQQLVRANS QISSVATAPA TPTPAANLST FASSSGGKQV NVAKVQEHIS
810 820 830 840 850
KLISQNEAIV ENKEILLQKK YPKQLSRSRS FNNANSNNAS QHGSNASALH
860 870 880 890 900
ANNSHNNTNA QMPERETKVN LAQAIFQKQQ HQLQQQQQQQ ITQQQQQQLE
910 920 930 940 950
QQNYYTYIQQ QQECQQQQLE PPNGVVKRNA YKPGVVMTTP VKQQQQLPPP
960 970 980 990 1000
PSPLPMQTMQ YRQDPATPVT KIEQPTTAVP VMPLNLSAKP KPTLVTVPVS
1010 1020 1030 1040 1050
SLSTSSLAPT PTTSTNPTSS SKTAPPPAQV NNSIIKNLLL NARGLAVPIG
1060 1070 1080 1090 1100
EGDDAVYSCP ICASEFRSAD DLKLHNSTYC QDASSSAPMS PASSPFRSNS
1110 1120 1130 1140 1150
ISLSLPELKS HMANSKNPLS LAKLAWSQLK TKRSSLVLSR LSAAQTPART
1160 1170 1180 1190 1200
STVTAPTVTA SAPAPAVATV TAPSSAPAPQ IEALRFVDAP LPSPGPLLGK
1210 1220 1230 1240 1250
TPLVDYAQQS TPRKAQDSVV ITKMHEDRQF VIEAQPAKRI KTSDLVVASS
1260 1270 1280 1290 1300
SQQPTSFNFS FNNQNSSNSV PELQSSKEER LRRFTSSGGS MIPISECPDL
1310 1320 1330 1340 1350
DNSPKMIRTP LLSGGSFQDV SVKVNNETGS SSKERKLMAL VSGSGLLGVS
1360 1370 1380 1390 1400
SGPQHFQFPP INSITAFNPL TLPPMSGGDK TTPVTPIPHV PGMPGPGSLT
1410 1420 1430 1440 1450
PQMPLLPPPP QQLQLPIPSS RGRSPNRKQP SPLLLGGGSG ELKALSPFGG
1460 1470 1480 1490 1500
VQNVPSEFSR QPPTPAQRQA LQWNSKETPK KAPFNFLRMA DNVKTTEPEV
1510 1520 1530 1540 1550
RHFNLENVIS GKQQELPLTP LHVDTPNGNA PEETSPVASA SASAKSKFLR
1560 1570 1580 1590 1600
PTSLPLKPGT FTPKRHHGIT PTANTLPLIS PETPRPSKSC VQLYLNGHAY
1610 1620 1630 1640 1650
TYLGLKCSTK MFYCTVNCPQ PSYVAGMHKL SMYSVWQVCE ENQPHPLGFK
1660 1670 1680 1690 1700
LKQVMALYDS RQRMLGNGSS TAMAGSGKLS YNLVASQQIV SSPSTSSTSS
1710 1720 1730 1740 1750
AFYQGPLKTP PTVTIAALSE ANVAAKANEE AQAKKLETSP SGQPLVGGYE
1760 1770 1780 1790 1800
SHEDYTYIRG RGRGRYVCSE CGIRCKKPSM LKKHIRTHTD VRPFTCSHCN
1810 1820 1830 1840 1850
FSFKTKGNLT KHMQSKTHFK KCIELGINPG PMPPDSEFLD VDMDFDQQSS
1860 1870 1880 1890 1900
TSAGGRTSSM AGESDSDDYS DNESESSDTD ESKSRQKEHE AARGLLSLSM
1910 1920 1930 1940 1950
TPPIPQSVSP YPQLQDTPLP AASPANSIGS SGSQPKRLVC SFTSPKPPFD
1960 1970 1980 1990 2000
YQKQEQYYSN PEESKPKRSV ANEESAPMDL TKPRGSILLI SPSPVSVPAH
2010 2020 2030 2040 2050
DLPKSQAQQM HDVIFGTSGN ESGFMKTLIS VSDKVRISAE MEEQAKHEAE
2060 2070 2080 2090 2100
GEDVQLQTYI KEHALHQAKI KQSQFSRSYL INTLYTAASP VMSSSSTLFT
2110 2120 2130 2140 2150
ANSRPVMSVN EVPSIEVHEV KTPEAIESPR SAPEQAPVIL AQIAQEENEE
2160 2170 2180 2190 2200
PNIAEPHNAN LPAAVQQPDV NEFTGVLGNP TAPPTSSVTA TSVSTTTAAP
2210 2220 2230 2240 2250
VAPSSTANST QPAQRTVIVG EDGFKSSTPT SKIGDLQHVS YGRGVPPAPI
2260 2270 2280 2290 2300
AGDARPTCTM CSKTFQRQHQ LTLHMNIHYM ERKFKCEPCS ISFRTQGHLQ
2310 2320 2330 2340 2350
KHERSEAHKN KVMMTSTFGV PTTSNPRPFE CTDCKIAFRI HGHLAKHLRS
2360 2370 2380 2390 2400
KTHVQKLECL QKLPFGTYAE IERAGISLTE IDTSDCENSL ISLKLLAQKL
2410 2420 2430 2440 2450
QEKDPGKLSS YTTPSGMMQL AQDAAGPVSQ DSASEDGFSA AIASAIASLD
2460 2470 2480 2490 2500
NDSAGNTPKR ASSMSEDETV ANGLNHSLKR RLPGSFSSTG EESDNPPESS
2510 2520
GEKRARSGQE LPLPVAVPVA ASAAASN
Length:2,527
Mass (Da):271,536
Last modified:November 1, 1996 - v1
Checksum:iF4FE6393CD477F8C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U31368 mRNA Translation: AAA92297.1
PIRiA56922
A56923

Similar proteinsi

Entry informationi

Entry nameiQ24107_DROME
AccessioniPrimary (citable) accession number: Q24107
Entry historyiIntegrated into UniProtKB/TrEMBL: November 1, 1996
Last sequence update: November 1, 1996
Last modified: March 28, 2018
This is version 121 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health