Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Proline iminopeptidase

Gene

TTHERM_00049020

Organism
Tetrahymena thermophila (strain SB210)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

Release of N-terminal proline from a peptide.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei119NucleophileUniRule annotation1
Active sitei276UniRule annotation1
Active sitei304Proton donorUniRule annotation1

GO - Molecular functioni

Keywordsi

Molecular functionAminopeptidaseUniRule annotation, Hydrolase, Protease

Protein family/group databases

ESTHERitetts-q23d89. Proline_iminopeptidase.
MEROPSiS33.001.

Names & Taxonomyi

Protein namesi
Recommended name:
Proline iminopeptidaseUniRule annotation (EC:3.4.11.5UniRule annotation)
Short name:
PIPUniRule annotation
Alternative name(s):
Prolyl aminopeptidaseUniRule annotation
Gene namesi
ORF Names:TTHERM_00049020Imported
OrganismiTetrahymena thermophila (strain SB210)Imported
Taxonomic identifieri312017 [NCBI]
Taxonomic lineageiEukaryotaAlveolataCiliophoraIntramacronucleataOligohymenophoreaHymenostomatidaTetrahymeninaTetrahymenidaeTetrahymena
Proteomesi
  • UP000009168 Componenti: Unassembled WGS sequence

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotation

Interactioni

Protein-protein interaction databases

STRINGi5911.EAR94511.

Structurei

3D structure databases

ProteinModelPortaliQ23D89.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini46 – 307AB hydrolase-1InterPro annotationAdd BLAST262

Sequence similaritiesi

Belongs to the peptidase S33 family.UniRule annotation

Phylogenomic databases

InParanoidiQ23D89.
KOiK01259.
OMAiCAWEDAV.

Family and domain databases

Gene3Di3.40.50.1820. 1 hit.
InterProiView protein in InterPro
IPR029058. AB_hydrolase.
IPR000073. AB_hydrolase_1.
IPR002410. Peptidase_S33.
IPR005944. Pro_iminopeptidase.
PfamiView protein in Pfam
PF00561. Abhydrolase_1. 1 hit.
PIRSFiPIRSF006431. Pept_S33. 1 hit.
PRINTSiPR00793. PROAMNOPTASE.
SUPFAMiSSF53474. SSF53474. 1 hit.
TIGRFAMsiTIGR01249. pro_imino_pep_1. 1 hit.

Sequencei

Sequence statusi: Complete.

Q23D89-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNQESENYRK TPFEIKEPFK SGFLKVSEIH TIYWEVSGNP EGKPAIIIHG
60 70 80 90 100
GPGSQSNPNN RGFFNPEIYM IVQFDQRGCG KSTPFAVTEE NTTQDLIKDI
110 120 130 140 150
ETIRDLLKLE VWHTVFGGSW GSTLAIYYAE TYPQKVKHLI LRGIFTGGQK
160 170 180 190 200
EMDFFYQNGT NWIFPDYYES FCNALPEVKR NNLLHNYHQL FNSDVNEETK
210 220 230 240 250
KQLAIEWTKY ESAISYFKVP DNFQKEIEED QSVLSIAKLE SHYFANGCFF
260 270 280 290 300
EKENQLIQDA HLISHIPTII VNGRYDIVTP LKVAWDLHKQ IKNSQLVIVP
310 320
DAGHLASEPG IKEQLIIATQ KFEKN
Length:325
Mass (Da):37,463
Last modified:April 18, 2006 - v1
Checksum:i7BCF5282DFAFBE6B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
GG662712 Genomic DNA. Translation: EAR94511.1.
RefSeqiXP_001014797.1. XM_001014797.1.

Genome annotation databases

EnsemblProtistsiEAR94511; EAR94511; TTHERM_00049020.
GeneIDi7839774.
KEGGitet:TTHERM_00049020.

Similar proteinsi

Entry informationi

Entry nameiQ23D89_TETTS
AccessioniPrimary (citable) accession number: Q23D89
Entry historyiIntegrated into UniProtKB/TrEMBL: April 18, 2006
Last sequence update: April 18, 2006
Last modified: September 27, 2017
This is version 67 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported